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Aardvark Therapeutics, Inc. (AARD)

Aardvark Therapeutics, Inc. is a biopharmaceutical firm in its clinical development phase, concentrating on developing small-molecule treatments. These therapies are designed to stimulate the body's natural regulatory systems (innate homeostatic pathways) to combat metabolic disorders. The company's primary experimental drug, ARD-101, is an orally administered, gut-specific small molecule. It functions as an agonist, targeting particular bitter taste receptors found within the gut lumen. ARD-101 is currently undergoing a Phase III clinical trial for managing excessive hunger (hyperphagia) associated with Prader-Willi Syndrome. Additionally, it is in a Phase II trial for addressing hyperphagia linked to acquired hypothalamic obesity, often a result of craniopharyngioma treatments like surgery or radiation therapy. Aardvark Therapeutics is also advancing ARD-201, which is currently in Phase I clinical trials for the treatment of obesity. Established in 2017, the company is based in San Diego, California.

Sector: Pharmaceutical Preparations

Industry: Biotechnology

Aardvark Therapeutics, Inc. Common Stock logo

Aardvark Therapeutics, Inc. Common Stock

NASDAQ:AARDHealthcare
-5.56%$1.36
AH$1.35-0.73%vs close
Mkt Cap$29.76M
Float14.55M
O/S21.88M
Vol
$ Vol
RVOL
Inst Own43.0%
SI3.8%
Earnings
Dilution
Upcoming Catalysts
  • ARD-101READOUT
    Cash runway at this date: 9mo
    Oct 23, 202610d ago8-K
  • ERAS-0015READOUT
    Cash runway at this date: 15mo
    Apr 27, 2026189d ago8-K
Phase Distribution
7 lead-sponsored trials·0 active·5 completed
Phase 24
Phase 32
Not applicable1

Trials need funding. See this company's dilution risk and cash position.

Clinical Trials
Status
Phase
  • Phase 3
    Terminated

    ARD-101 for Treatment of PWS: The Hunger Elimination or Reduction Objective Trial

    Placebo, ARD-101

    Hyperphagia, Prader-Willi Syndrome

    Enrollment
    68
    Start
    Dec 2024
    Primary Completion
    May 2026
    Completion
    May 2026
    NCT06828861
  • Phase 3
    Terminated

    The Hunger Elimination or Reduction Objective (HERO ) Open -Label Extension (OLE) Trial

    ARD-101

    Hyperphagia, Prader-Willi Syndrome +1

    Enrollment
    19
    Start
    Jul 2024
    Primary Completion
    Apr 2026
    Completion
    Apr 2026
    NCT07197034
  • Phase 2
    Completed

    Study to Evaluate ARD-101 in Adults With Obesity

    ARD-101, Placebo

    Obesity

    Enrollment
    20
    Start
    Nov 2021
    Primary Completion
    Nov 2022
    Completion
    Nov 2022
    NCT05121441
  • Phase 2
    Completed

    A Study of Oral ARD-101 in Patients With Prader-Willi Syndrome

    ARD-101

    Prader-Willi Syndrome

    Enrollment
    19
    Start
    May 2022
    Primary Completion
    Sep 2024
    Completion
    Sep 2024
    NCT05153434
  • Phase 2
    Completed

    Study to Evaluate ARD-101 in Adults Receiving Bariatric Surgery

    ARD-101

    Bariatric Surgery, Obesity +1

    Enrollment
    12
    Start
    Mar 2022
    Primary Completion
    Feb 2023
    Completion
    Feb 2023
    NCT05215847
  • Phase 2
    Completed

    A Study to Evaluate ARD-501 in Patients With Autism Spectrum Disorder

    Low Dose ARD-501, High Dose ARD-501

    Autism Spectrum Disorder

    Enrollment
    5
    Start
    Aug 2024
    Primary Completion
    Jan 2025
    Completion
    Jan 2025
    NCT06126653
  • Observational
    Completed

    Home Usability of a Nasal Lavage System in Children

    Use of an automatic nasal irrigator/aspirator

    Nasal Congestion, Respiratory Tract Infection +2

    Enrollment
    30
    Start
    Jul 2009
    Primary Completion
    Aug 2009
    Completion
    Aug 2009
    NCT01129765