Adaptive Biotechnologies Corp (ADPT)
Adaptive Biotechnologies Corporation, founded in 2009 and headquartered in Seattle, Washington (operating as Adaptive TCR Corporation until its name change in December 2011), is a commercial-stage entity focused on pioneering an immune medicine platform. This advanced platform is engineered for the precise diagnosis and effective treatment of a broad spectrum of illnesses. The company offers several core technological solutions. Its immunoSEQ platform, a foundational immunosequencing product, is vital for translational research and discovering novel prognostic and diagnostic markers. For confirming past COVID-19 infections, Adaptive provides T-Detect COVID. Additionally, clonoSEQ functions as a critical clinical diagnostic tool, enabling the detection and continuous monitoring of minimal residual disease in individuals with multiple myeloma, B-cell acute lymphoblastic leukemia, and chronic lymphocytic leukemia; it is also available as a CLIA-validated laboratory-developed test for other lymphoid cancers. Another specialized offering, immunoSEQ T-MAP COVID, aids vaccine developers and researchers in quantifying T-cell immune responses to vaccines. Beyond its current product lineup, Adaptive Biotechnologies actively develops a pipeline of clinical products and services designed for the diagnosis, monitoring, and treatment of conditions such as cancer, autoimmune disorders, and infectious diseases. Its solutions cater to life science research, clinical diagnostics, and drug discovery applications. The company has established key strategic collaborations: one with Genentech, Inc., for the joint development, manufacturing, and commercialization of neoantigen-directed T-cell therapies aimed at treating various cancers; and another with Microsoft Corporation, dedicated to creating sophisticated diagnostic tests capable of identifying multiple diseases early from a single blood sample.
Sector: Biological Products, (No Diagnostic Substances)
Industry: Biotechnology
Adaptive Biotechnologies Corporation
Trials need funding. See this company's dilution risk and cash position.
- ObservationalCompleted
ImmuneSense Lyme Study
T-Detect Lyme
Lyme Disease
NCT04422314Enrollment893StartJul 2020Primary CompletionOct 2021CompletionOct 2021 - ObservationalCompleted
ImmuneRACE - Immune Response Action to COVID-19 Events
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Covid19
NCT04494893Enrollment808StartApr 2020Primary CompletionMar 2021CompletionApr 2021 - Not applicableTerminated
Implementing IntelliCare in Collaborative Care: A Quality Improvement Evaluation
IntelliCare, Treatment as Usual (TAU)
Depression
NCT04499729Enrollment318StartDec 2019Primary CompletionMay 2021CompletionMay 2021 - ObservationalTerminated
The clonoSEQ® Watch Registry
clonoSEQ Assay
Acute Lymphoblastic Leukemia, Adult B-Cell, Chronic Lymphocytic Leukemia +2
NCT04545333Enrollment465StartOct 2020Primary CompletionOct 2023CompletionOct 2023 - ObservationalCompleted
ImmuneSense™ COVID-19 Study
T-Detect™ SARS-CoV-2 Assay
Coronavirus Disease (COVID-19), SARS-CoV-2 Infection
NCT04583982Enrollment180StartOct 2020Primary CompletionDec 2020CompletionDec 2020 - ObservationalCompleted
ImmuneSense COVID-19 Variant Study
T-Detect COVID test
Covid19
NCT05054088Enrollment203StartOct 2021Primary CompletionJul 2022CompletionJul 2022 - ObservationalWithdrawn
ImmuneSense™ COVID-19 Cross-Reactivity Study
-
Coronavirus Disease, SARS-CoV-2 Infection
NCT05112874Enrollment0StartDec 2021Primary CompletionMay 2023CompletionMay 2023 - ObservationalRecruiting
Optimizing ctDNA-based MRD Assessment in DLBCL, MCL, and FL Patients Undergoing CAR Therapy
ClonoSEQ
Follicular Lymphoma, Diffuse Large B Cell Lymphoma +1
NCT05255354Enrollment300StartJun 2022Primary CompletionSep 2025est.CompletionDec 2026est. - Not applicableCompleted
Integrating a Suite of Mental Health Apps for Depression in a Healthcare Setting
IntelliCare
Depression, Anxiety
NCT05274620Enrollment82StartMay 2022Primary CompletionApr 2024CompletionApr 2024 - ObservationalTerminated
ImmuneSense™ IBD Study
-
Inflammatory Bowel Diseases
NCT05769829Enrollment484StartOct 2022Primary CompletionAug 2023CompletionAug 2023
| Drug / Therapy | Link | ||
|---|---|---|---|
| Observational | Completed | T-Detect Lyme | NCT04422314 |
| Observational | Completed | - | NCT04494893 |
| Not applicable | Terminated | IntelliCare, Treatment as Usual (TAU) | NCT04499729 |
| Observational | Terminated | clonoSEQ Assay | NCT04545333 |
| Observational | Completed | T-Detect™ SARS-CoV-2 Assay | NCT04583982 |
| Observational | Completed | T-Detect COVID test | NCT05054088 |
| Observational | Withdrawn | - | NCT05112874 |
| Observational | Recruiting | ClonoSEQ | NCT05255354 |
| Not applicable | Completed | IntelliCare | NCT05274620 |
| Observational | Terminated | - | NCT05769829 |