Avalo Therapeutics, Inc. (AVTX)
Avalo Therapeutics, Inc. is a precision medicine company in the clinical development phase, dedicated to identifying, advancing, and marketing specialized treatments for patients experiencing critical unmet medical needs across the fields of immunology, immuno-oncology, and rare genetic disorders. Among its key pipeline assets is AVTX-002, a fully human monoclonal antibody designed to inhibit LIGHT. This drug is currently undergoing Phase II clinical trials for non-eosinophilic asthma and inflammatory bowel diseases, specifically moderate to severe Crohn's disease and ulcerative colitis. Furthermore, AVTX-002 is also being investigated in Phase III for its potential to treat acute respiratory distress syndrome caused by COVID-19. The company is also advancing AVTX-007, a fully human monoclonal antibody targeting IL-18, which is progressing through Phase I clinical studies for Still's disease, encompassing both adult-onset Still's disease and systemic juvenile idiopathic arthritis. Avalo's late-stage pipeline includes two products addressing rare genetic conditions, both in Phase III clinical trials: AVTX-801, a D-galactose substrate replacement therapy for phosphoglucomutase 1 deficiency (PGM1), also known as PGM1-CDG; and AVTX-803, an L-fucose substrate replacement therapy intended for LADII, medically referred to as SLC35C1-CDG. Established in 2011, the corporation initially operated as Cerecor Inc. before rebranding as Avalo Therapeutics, Inc. in August 2021. Its main operations are situated in Rockville, Maryland.
Sector: Pharmaceutical Preparations
Industry: Biotechnology
Avalo Therapeutics, Inc.
NASDAQ:AVTXHealthcare · Biotechnology
-3.63%$7.17
AH$7.17+0.00%vs close
Mkt Cap$384.53M
Float48.59M
O/S53.63M
Vol
$ Vol
RVOL
Inst Own-
Earnings
Dilution
Financials Summary
Revenue$59K
Net Income-$78.26M
Total Assets$116.46M
Free Cash Flow-$51.46M
Debt & Equity
Debt 3%
Equity 97%
Total Debt$2.43M
Total Equity$83.05M
Shares Outstanding
Short Interest
Split History3 splits · 3 reverse
- 1:240Reverse splitDec 29, 2023240 shares → 1
- 1:12Reverse splitJul 8, 202212 shares → 1
- 1:51Reverse splitSep 10, 200751 shares → 1
Balance Sheet Details
Assets$116.46M
Liabilities$33.41M
Accounts Receivable$0
Accounts Payable$137K
Inventory$0
PP&E (Net)$460K
Goodwill$10.5M
Intangible Assets$0
Income Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 | FY 2014 | FY 2013 | FY 2012 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 | 2014-12-31 | 2013-12-31 | 2012-12-31 |
| Revenue | $59K | $441K | $1.92M | $18.05M | $5.4M | $6.7M | $6.75M | $18.33M | $27.81M | $1.15M | $0 | $0 | $0 | $83K |
| YoY Growth | -86.6% | -77.1% | -89.3% | 234.4% | -19.4% | -0.8% | -63.2% | -34.1% | 2312.2% | - | - | - | - | - |
| Cost of Revenue | $0 | -$366K | $1.28M | $3.43M | $1.49M | $300K | -$567K | $7.48M | $636K | $8.24M | $24K | $9.5M | $0 | $8.48M |
| Gross Profit | $59K | $807K | $640K | $14.62M | $3.91M | $6.4M | $7.32M | $10.85M | $27.18M | -$7.09M | -$24K | -$9.5M | $0 | -$8.39M |
| Gross Margin | 100.0% | 183.0% | 33.3% | 81.0% | 72.4% | 95.5% | 108.4% | 59.2% | 97.7% | -614.6% | - | - | - | -10142.4% |
| Research and Development | $50.08M | $52.08M | $13.78M | $31.31M | $59.84M | $32.19M | $11.76M | $5.79M | $4.37M | $10.15M | $6.59M | $12.24M | $8.91M | $8.48M |
| Selling, General, and Administrative | $22.9M | $17.24M | $10.3M | $20.71M | $24.66M | $19.76M | $11.61M | $19.2M | $8.91M | $7.08M | $4.42M | $4.88M | $4.02M | $2.1M |
| Other | $0 | $0 | $3.91M | $38K | $1.55M | -$45.55M | $83K | $14K | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Operating Expenses | $72.98M | $69.32M | $27.99M | $52.06M | $86.04M | $6.4M | $23.45M | $29.52M | $13.29M | $17.23M | $11.01M | $17.12M | $12.93M | $2.1M |
| Operating Income (EBIT) | -$72.92M | -$68.51M | -$27.35M | -$37.44M | -$82.13M | $0 | -$16.14M | -$39.31M | $13.89M | -$16.08M | -$11.01M | -$17.12M | -$12.93M | -$10.49M |
| Operating Margin | -123601.7% | -15535.6% | -1421.6% | -207.4% | -1521.6% | - | -239.1% | -214.5% | 49.9% | -1394.6% | - | - | - | -12676.4% |
| Interest Expense | $0 | $0 | $3.42M | $4.17M | $2.39M | $0 | $0 | $0 | $24K | $464K | $793K | $1.21M | $11K | $0 |
| Interest Income | $4.35M | $3.32M | $0 | $0 | $0 | $49K | $121K | $16K | $0 | $0 | $0 | $0 | $0 | $1K |
| Other Income (Expense) | -$5.17M | $33.5M | -$4.18M | -$4.19M | -$2.41M | -$67.18M | $147K | $55K | -$54K | -$392K | $520K | $1.06M | -$111K | $1K |
| Income Before Tax (EBT) | -$78.09M | -$35.02M | -$31.53M | -$41.63M | -$84.55M | -$67.18M | -$15.99M | -$40.09M | $13.84M | -$16.47M | -$10.49M | -$16.06M | -$13.05M | -$10.49M |
| Income Tax Expense | $165K | $114K | $14K | $28K | -$196K | -$2.79M | $280K | -$34K | $1.97M | $364K | -$544K | $0 | $111K | $0 |
| Net Income | -$78.26M | -$35.13M | -$31.54M | -$41.66M | -$84.38M | -$63.5M | -$16.07M | -$40.05M | $11.87M | -$16.47M | -$10.49M | -$16.06M | -$13.05M | -$10.49M |
| Net Income Margin | -132642.4% | -7965.8% | -1639.5% | -230.8% | -1563.1% | -947.9% | -238.1% | -218.5% | 42.7% | -1428.5% | - | - | - | -12674.7% |
| Supplementary Data | ||||||||||||||
| EPS | -5.84 | -4.32 | -113.58 | -1062.65 | -2330.66 | -2523.77 | -819.74 | -3317.28 | 1856.88 | -21.93 | -16.21 | -41.61 | -43.12 | -199.77 |
| Diluted EPS | -5.84 | -3.26 | -113.58 | -1062.65 | -2330.66 | -2523.77 | -819.74 | -3317.28 | 1822.74 | -21.93 | -16.21 | -41.61 | -43.12 | -199.77 |
| Weighted Average OS | 13.40M | 8.13M | 277,727 | 39,202 | 36,191 | 25,511 | 19,849 | 12,074 | 6,392 | 3,066 | 773 | 385,845 | 302,554 | 52,509 |
| EBITDA | -$77.75M | -$34.85M | -$23.29M | -$37.29M | -$80.5M | -$45.45M | -$13.51M | -$13.05M | $14.35M | -$16.05M | -$10.46M | -$17.09M | -$12.91M | -$10.48M |
| EBITDA Margin | -131779.7% | -7901.6% | -1210.3% | -206.6% | -1491.2% | -678.5% | -200.1% | -71.2% | 51.6% | -1392.3% | - | - | - | -12658.2% |
Balance Sheet
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 | FY 2014 | FY 2013 | FY 2012 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 | 2014-12-31 | 2013-12-31 | 2012-12-31 |
| Assets | ||||||||||||||
| Current Assets | ||||||||||||||
| Cash and Cash Equivalents | $15.86M | $134.55M | $7.42M | $13.17M | $54.59M | $18.92M | $3.61M | $10.65M | $2.47M | $5.13M | $21.16M | $11.74M | $3.42M | $9.52M |
| Short-Term Investments | $82.48M | $0 | $0 | $0 | $0 | $0 | $7.63M | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Cash and Short-Term Investments | $98.34M | $134.55M | $7.42M | $13.17M | $54.59M | $18.92M | $11.24M | $10.65M | $2.47M | $5.13M | $21.16M | $11.74M | $3.42M | $9.52M |
| Accounts Receivable | $0 | $611K | $136K | $1.92M | $4.8M | $4.38M | $5.24M | $6.08M | $2.94M | $132K | $0 | $0 | $0 | $0 |
| Inventory | $0 | $0 | $0 | $20K | $38K | $3K | $21K | $1.11M | $382K | $11K | $0 | $0 | $0 | $0 |
| Other Current Assets | $6.95M | $3.73M | $844K | $1.3M | $51K | $38K | $515K | $9.41M | $4.18M | $11K | $59K | $58K | $0 | $430K |
| Total Current Assets | $105.29M | $138.89M | $8.39M | $16.42M | $61.84M | $26M | $17.72M | $21.93M | $10.99M | $5.66M | $21.62M | $12.16M | $4.14M | $9.95M |
| Long-Term Assets | ||||||||||||||
| Property, Plant & Equipment Net | $460K | $1.21M | $1.97M | $2.41M | $2.69M | $1.61M | $1.45M | $587K | $45K | $43K | $35K | $39K | $66K | $57K |
| Goodwill | $10.5M | $10.5M | $10.5M | $14.41M | $14.41M | $14.41M | $14.41M | $16.41M | $14.29M | $0 | $0 | $0 | $0 | $0 |
| Intangible Assets | $0 | $0 | $0 | $0 | $38K | $1.58M | $2.43M | $31.24M | $17.66M | $0 | $0 | $0 | $0 | $0 |
| Long-Term Investments | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $82K | $131K | $63K | $0 | $0 | $0 | $0 |
| Deferred Tax Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $91K | -$131K | $0 | $0 | $0 | $0 | $0 |
| Other Long-Term Assets | $210K | $131K | $131K | $131K | $1.23M | $149K | $102K | -$91K | $131K | $173 | $0 | $117K | $874K | -$57K |
| Total Long-Term Assets | $11.17M | $11.84M | $12.6M | $16.95M | $18.37M | $17.75M | $18.38M | $48.32M | $32.13M | $106K | $35K | $156K | $940K | $57K |
| Other Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $13K |
| Total Assets | $116.46M | $150.73M | $20.99M | $33.37M | $80.21M | $43.76M | $36.11M | $70.25M | $43.12M | $5.77M | $21.66M | $12.32M | $5.08M | $10.02M |
| Liabilities | ||||||||||||||
| Current Liabilities | ||||||||||||||
| Accounts Payable | $137K | $283K | $446K | $2.88M | $3.37M | $2.57M | $2.08M | $1.45M | $1.3M | $1.01M | $678K | $931K | $1.64M | $821K |
| Short-Term Debt | $0 | $0 | $0 | $5.93M | $0 | $0 | $0 | $0 | $0 | $2.35M | $3.21M | $1.91M | $0 | $0 |
| Current Income Tax Payable | $0 | $0 | $0 | $0 | $0 | $0 | $552K | $2.03M | $2.26M | $0 | $0 | $0 | $0 | $0 |
| Current Unearned Revenue | $0 | $0 | $0 | $88K | $0 | $0 | $0 | $2.03M | $0 | $943K | $1.89M | $975K | $0 | $0 |
| Other Current Liabilities | $12.41M | $3.24M | $3.06M | $3.18M | $4.32M | $4.57M | $5.57M | $21.14M | $8.71M | $675K | $836K | $1.18M | $432K | $723K |
| Total Current Liabilities | $12.94M | $6.96M | $4.62M | $22.11M | $19.89M | $15.22M | $12.16M | $26.22M | $11.41M | $4.31M | $5.85M | $4.99M | $3.07M | $1.54M |
| Long-Term Liabilities | ||||||||||||||
| Long-Term Debt | $2M | $0 | $0 | $13.49M | $32.83M | $0 | $0 | $0 | $0 | $0 | $2.35M | $5.31M | $0 | $0 |
| Long-Term Unearned Revenue | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Long-Term Deferred Tax Liabilities | $434K | $270K | $155K | $141K | $113K | $90K | $86K | $69K | $7K | $0 | $0 | $0 | $0 | $0 |
| Other Long-Term Liabilities | $18M | $10.47M | $8.92M | $8.54M | $4.3M | $3.88M | $2.87M | $23.06M | $3.85M | $1.25M | $371K | $28.35M | $19.86M | $0 |
| Total Long-Term Liabilities | $20.47M | $10.74M | $9.07M | $22.17M | $37.24M | $3.97M | $2.95M | $23.13M | $3.86M | $1.25M | $8.57M | $33.65M | $19.86M | $0 |
| Other Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | -$5.85M | $0 | $0 | $0 |
| Total Liabilities | $33.41M | $17.7M | $13.69M | $44.28M | $57.13M | $19.19M | $15.11M | $49.34M | $15.26M | $5.56M | $8.57M | $38.65M | $22.92M | $1.54M |
| Stockholders' Equity | ||||||||||||||
| Preferred Stock | $0 | $0 | $0 | $0 | $0 | $1K | $3K | $3K | $0 | $0 | $21.66B | $28.35M | $19.86M | $19.86M |
| Common Stock | $18K | $10K | $1K | $0 | $9K | $75K | $44K | $41K | $2.69M | $9K | $9K | $650 | $643 | $18K |
| Retained Earnings | -$448.52M | -$370.26M | -$335.13M | -$303.82M | -$262.17M | -$177.79M | -$114.29M | -$98.22M | -$58.17M | -$70.04M | -$53.56M | -$43.07M | -$27.02M | -$13.97M |
| Comprehensive Income & Other | $68K | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $2.66M | $0 | -$21.66B | -$28.35M | -$19.86M | $0 |
| Other Stockholders' Equity | $531.55M | $503.29M | $342.44M | $292.91M | $285.24M | $202.28M | $135.24M | $119.09M | $83.34M | $70.23M | $66.64M | $16.74M | $9.17M | $22.43M |
| Total Equity | $83.05M | $133.03M | $7.3M | -$10.91M | $23.08M | $24.56M | $21M | $20.91M | $27.86M | $207K | $13.08M | -$26.33M | -$17.85M | $8.48M |
| Minority Interest | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities and Equity | $116.46M | $150.73M | $20.99M | $33.37M | $80.21M | $43.76M | $36.11M | $70.25M | $43.12M | $5.77M | $21.66M | $12.32M | $5.08M | $10.02M |
| Supplementary Data | ||||||||||||||
| Total Debt | $2.43M | $568K | $537K | $19.95M | $33.32M | $426K | $156K | $15.38M | $0 | $2.35M | $5.56M | $7.21M | $0 | $0 |
| Net Debt | -$13.43M | -$133.98M | -$6.88M | $6.78M | -$21.27M | -$18.49M | -$3.45M | $4.73M | -$2.47M | -$2.77M | -$15.6M | -$4.53M | -$3.42M | -$9.52M |
Cash Flow Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 | FY 2014 | FY 2013 | FY 2012 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 | 2014-12-31 | 2013-12-31 | 2012-12-31 |
| Operating Activities | ||||||||||||||
| Net Income | -$78.26M | -$35.13M | -$31.54M | -$41.66M | -$84.38M | -$63.5M | -$16.07M | -$40.05M | $11.87M | -$16.47M | -$10.49M | -$16.06M | -$13.05M | -$10.49M |
| Depreciation & Amortization | $344K | $169K | $158K | $166K | $1.66M | $1.84M | $3.88M | $1.85M | $425K | $27K | $24K | $29K | $20K | $15K |
| Deferred Income Tax | $165K | $114K | $14K | $28K | $22K | $197K | $17K | -$17K | -$833K | -$73K | -$1.31M | -$1.18M | $0 | $0 |
| Stock-Based Compensation | $13.62M | $5.85M | $3.48M | $7.55M | $8.17M | $6.79M | $2.53M | $2.43M | $1.16M | $1.69M | $395K | $1.09M | $749K | $588K |
| Changes in Working Capital: | ||||||||||||||
| Accounts Receivable | $0 | -$475K | $1.78M | $2.88M | $1.12M | -$2.79M | $6.78M | -$223K | -$247K | -$132K | $0 | $0 | $0 | $0 |
| Inventory | $0 | $0 | $20K | $18K | -$35K | $18K | $533K | -$311K | -$203K | $0 | $0 | $0 | $0 | $0 |
| Accounts Payable | -$146K | -$163K | -$2.44M | -$487K | $796K | $99K | $1.02M | $82K | $96K | $332K | -$269K | -$708K | $818K | $0 |
| Other Working Capital | $3.99M | -$4.07M | -$8.61M | -$2.47M | $961K | -$1.77M | -$10.36M | $9.18M | -$113K | -$245K | $1.2M | $325K | -$174K | $0 |
| Total Working Capital Change | $3.84M | -$4.71M | -$9.24M | -$60K | $2.84M | -$4.44M | -$2.03M | $8.73M | -$467K | $87K | $928K | -$383K | $644K | $0 |
| Other Non-Cash Items | $8.83M | -$15.35M | $6.46M | $7.22M | $794K | $18.57M | -$7.47M | $23.93M | $366K | $162K | $294K | $989K | $147K | $1.19M |
| Net Cash from Operating | -$51.46M | -$49.06M | -$30.68M | -$26.75M | -$70.89M | -$40.54M | -$19.13M | -$3.13M | $12.52M | -$14.57M | -$10.16M | -$15.52M | -$11.49M | -$9.29M |
| Investing Activities | ||||||||||||||
| Capital Expenditures | $0 | $0 | -$158K | -$95K | -$113K | -$63K | -$262K | -$564K | -$23K | -$35K | -$20K | -$20K | -$29K | -$12K |
| Acquisitions | $0 | $356K | $0 | $0 | $0 | $11.2M | $0 | $1.43M | -$18.89M | $0 | $0 | $0 | $0 | $0 |
| Purchases of Investments | -$113.72M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Sales of Investments | $31.31M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Investing Activities | $690K | $0 | $25K | $0 | $0 | $0 | -$181K | -$1K | $0 | $0 | $0 | $0 | $0 | $0 |
| Net Cash from Investing | -$81.72M | $356K | -$133K | -$95K | -$113K | $11.13M | -$443K | $865K | -$18.91M | -$35K | -$20K | -$20K | -$29K | -$12K |
| Financing Activities | ||||||||||||||
| Debt Repaid | - | - | $21.24M | $14.81M | -$32.9M | - | $256K | - | $2.37M | $3.31M | $1.81M | -$9.64M | - | - |
| Common Stock Issuance | $15.1M | $115.63M | $46.22M | $107K | $71.93M | $44.45M | $12.68M | $3.86M | $6.34M | $2M | $23.69M | $0 | $0 | $0 |
| Common Stock Repurchases | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Dividends Paid | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Financing Activities | -$510K | $60.22M | $67K | $0 | $1.93M | $332K | $131K | $6.55M | -$232K | -$115K | -$2.27M | -$365K | -$699K | $17.71M |
| Net Cash from Financing | $14.59M | $175.85M | $25.04M | -$14.7M | $106.76M | $44.78M | $12.56M | $10.4M | $3.74M | -$1.43M | $19.6M | $23.86M | $5.42M | $17.71M |
| Forex Effect | $0 | $0 | $0 | $96K | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | -$118.59M | $127.15M | -$5.77M | -$41.45M | $35.76M | $15.38M | -$7.02M | $8.14M | -$2.66M | -$16.03M | $9.42M | $8.32M | -$6.1M | $8.41M |
| Supplementary Data | ||||||||||||||
| Operating Cash Flow | -$51.46M | -$49.06M | -$30.68M | -$26.75M | -$70.89M | -$40.54M | -$19.13M | -$3.13M | $12.52M | -$14.57M | -$10.16M | -$15.52M | -$11.49M | -$9.29M |
| Capital Expenditure | $0 | $0 | -$158K | -$95K | -$113K | -$63K | -$262K | -$564K | -$23K | -$35K | -$20K | -$20K | -$29K | -$12K |
| Free Cash Flow | -$51.46M | -$49.06M | -$30.84M | -$26.85M | -$71M | -$40.6M | -$19.4M | -$3.69M | $12.5M | -$14.61M | -$10.18M | -$15.54M | -$11.51M | -$9.3M |
| Cash at Beginning | $134.7M | $7.55M | $13.32M | $54.64M | $19.11M | $3.73M | $10.75M | $2.61M | $5.13M | $21.16M | $11.74M | $3.42M | $9.52M | $1.11M |
| Cash at End | $16.11M | $134.7M | $7.55M | $13.19M | $54.86M | $19.11M | $3.73M | $10.75M | $2.47M | $5.13M | $21.16M | $11.74M | $3.42M | $9.52M |