Axsome Therapeutics, Inc. (AXSM)
Axsome Therapeutics, Inc. is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for a range of central nervous system (CNS) disorders within the United States. Its robust product pipeline features several promising candidates, including: AXS-05, an investigational therapy currently being developed for major depressive disorder and treatment-resistant depression. This compound is also in Phase III clinical evaluation for Alzheimer's disease agitation and has successfully finished Phase II trials investigating its use for smoking cessation. AXS-07, a novel, orally administered, rapidly-acting investigational medicine that employs multiple mechanisms of action. It has concluded two Phase III studies for the acute treatment of migraine attacks. AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is presently undergoing a Phase III trial for narcolepsy. AXS-14, an oral investigational drug, advancing through Phase III trials for the management of fibromyalgia. Axsome Therapeutics also engages in a research collaboration with Duke University to further assess AXS-05's potential in smoking cessation. The company, established in 2012, has its main offices in New York, New York.
Sector: Pharmaceutical Preparations
Industry: Biotechnology
Axsome Therapeutics, Inc.
NASDAQ:AXSMHealthcare · Biotechnology
+0.68%$144.43
AH$146.85+1.68%vs close
Mkt Cap$7.57B
Float40.93M
O/S52.38M
Vol
$ Vol
RVOL
Inst Own72.7%
SI7.6%
Earnings
Dilution
Financials Summary
Revenue$638.5M
Net Income-$183.17M
Total Assets$689.8M
Free Cash Flow-$93.89M
Debt & Equity
Debt 73%
Equity 27%
Total Debt$241.29M
Total Equity$88.3M
Shares Outstanding
Short Interest
Split History
No splits on record
Nothing in AXSM's public trading history: no forward or reverse split has affected the share count.
Balance Sheet Details
Assets$689.8M
Liabilities$601.51M
Accounts Receivable$224.46M
Accounts Payable$65.54M
Inventory$27.94M
PP&E (Net)$20.86M
Goodwill$12.04M
Intangible Assets$40.52M
Income Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 | FY 2014 | FY 2013 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 | 2014-12-31 | 2013-12-31 |
| Revenue | $638.5M | $385.69M | $270.6M | $50.04M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| YoY Growth | 65.5% | 42.5% | 440.8% | - | - | - | - | - | - | - | - | - | - |
| Cost of Revenue | $47.48M | $33.3M | $26.07M | $5.2M | $0 | $0 | $37K | $49K | $43K | $20K | $4K | $0 | $0 |
| Gross Profit | $591.02M | $352.39M | $244.53M | $44.84M | $0 | $0 | -$37K | -$49K | -$43K | -$20K | -$4K | $0 | $0 |
| Gross Margin | 92.6% | 91.4% | 90.4% | 89.6% | - | - | - | - | - | - | - | - | - |
| Research and Development | $183.28M | $187.08M | $97.94M | $57.95M | $58.06M | $70.24M | $53.65M | $23.5M | $19.96M | $21.2M | $6.78M | $4.28M | $1.54M |
| Selling, General, and Administrative | $570.6M | $411.36M | $323.12M | $159.25M | $66.65M | $28.9M | $13.6M | $9.35M | $7.21M | $6.34M | $2.42M | $1.39M | $304K |
| Other | $6.38M | $34.52M | $55.29M | $7.44M | $0 | -$54K | -$139K | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Operating Expenses | $760.25M | $632.95M | $476.36M | $224.64M | $124.71M | $99.14M | $67.11M | $32.85M | $27.16M | $27.54M | $9.2M | $5.67M | $1.84M |
| Operating Income (EBIT) | -$169.24M | -$280.56M | -$231.82M | -$179.8M | -$124.71M | -$99.14M | -$67.25M | -$32.85M | -$27.16M | -$27.54M | -$9.2M | -$5.67M | -$1.84M |
| Operating Margin | -26.5% | -72.7% | -85.7% | -359.3% | - | - | - | - | - | - | - | - | - |
| Interest Expense | $6.56M | $6.57M | $6.45M | $7.33M | $5.7M | $2.57M | $1.24M | $1.13M | $1.34M | $132K | $915K | $2.23M | $327K |
| Interest Income | $9.37M | $0 | $0 | $0 | $0 | $2.57M | $1.24M | $0 | $0 | $0 | $915K | $2.23M | $0 |
| Other Income (Expense) | -$14.47M | -$6.57M | -$6.45M | -$7.33M | -$5.7M | -$3.76M | -$1.1M | $1.66M | -$1.78M | $342K | -$1.36M | -$329K | -$327K |
| Income Before Tax (EBT) | -$183.7M | -$287.13M | -$238.28M | -$187.13M | -$130.4M | -$102.9M | -$68.35M | -$30.97M | -$28.94M | -$27.2M | -$10.56M | -$6M | -$2.17M |
| Income Tax Expense | -$530K | $85K | $960K | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $1.36M | $0 | $0 |
| Net Income | -$183.17M | -$287.22M | -$239.24M | -$187.13M | -$130.4M | -$102.9M | -$68.35M | -$30.97M | -$28.94M | -$27.2M | -$12.21M | -$6M | -$2.17M |
| Net Income Margin | -28.7% | -74.5% | -88.4% | -374.0% | - | - | - | - | - | - | - | - | - |
| Supplementary Data | |||||||||||||
| EPS | -3.68 | -5.99 | -5.27 | -4.60 | -3.47 | -2.83 | -2.05 | -1.15 | -1.27 | -1.42 | -0.88 | -0.47 | -0.28 |
| Diluted EPS | -3.68 | -5.99 | -5.27 | -4.60 | -3.47 | -2.83 | -2.05 | -1.15 | -1.27 | -1.42 | -0.88 | -0.47 | -0.28 |
| Weighted Average OS | 49.75M | 47.91M | 45.43M | 40.66M | 37.62M | 37.21M | 34.02M | 26.88M | 22.76M | 19.15M | 11.95M | 12.72M | 7.82M |
| EBITDA | -$168.08M | -$272.6M | -$224.99M | -$175.4M | -$124.63M | -$100.31M | -$67.21M | -$32.58M | -$27.77M | -$27.52M | -$9.19M | -$697K | $0 |
| EBITDA Margin | -26.3% | -70.7% | -83.1% | -350.5% | - | - | - | - | - | - | - | - | - |
Balance Sheet
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 | FY 2014 | FY 2013 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 | 2014-12-31 | 2013-12-31 |
| Assets | |||||||||||||
| Current Assets | |||||||||||||
| Cash and Cash Equivalents | $322.93M | $315.35M | $386.19M | $200.84M | $86.47M | $183.88M | $219.97M | $13.97M | $34.02M | $36.62M | $48.04M | $2.62M | $2.09M |
| Short-Term Investments | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Cash and Short-Term Investments | $322.93M | $315.35M | $386.19M | $200.84M | $86.47M | $183.88M | $219.97M | $13.97M | $34.02M | $36.62M | $48.04M | $2.62M | $2.09M |
| Accounts Receivable | $224.46M | $142M | $94.82M | $37.7M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Inventory | $27.94M | $15.73M | $15.13M | $4.32M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Current Assets | $13.65M | $11.98M | $8.12M | $2.78M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $4K |
| Total Current Assets | $588.99M | $485.06M | $504.26M | $245.64M | $86.52M | $184.02M | $220.38M | $15.22M | $35.3M | $38M | $49.03M | $2.74M | $2.1M |
| Long-Term Assets | |||||||||||||
| Property, Plant & Equipment Net | $20.86M | $5.97M | $7.62M | $1.14M | $944K | $1.79M | $31K | $52K | $68K | $101K | $17K | $0 | $0 |
| Goodwill | $12.04M | $12.04M | $12.04M | $10.31M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Intangible Assets | $40.52M | $46.89M | $53.29M | $59.66M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Long-Term Investments | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Deferred Tax Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Long-Term Assets | $27.4M | $18.53M | $11.03M | $14.72M | $323K | $317K | $140K | $112K | $188K | $113K | $27K | $43K | $0 |
| Total Long-Term Assets | $100.82M | $83.43M | $83.97M | $85.83M | $1.27M | $2.11M | $170K | $164K | $256K | $214K | $43K | $43K | $0 |
| Other Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Assets | $689.8M | $568.5M | $588.24M | $331.48M | $87.79M | $186.13M | $220.55M | $15.38M | $35.56M | $38.21M | $49.08M | $2.79M | $2.1M |
| Liabilities | |||||||||||||
| Current Liabilities | |||||||||||||
| Accounts Payable | $65.54M | $72M | $40.68M | $38.6M | $13.15M | $13.5M | $10.94M | $3.69M | $3.44M | $4.08M | $1.89M | $758K | $159K |
| Short-Term Debt | $72.98M | $0 | $0 | $0 | $0 | $0 | $2.6M | $3.29M | $3.27M | $269K | $0 | $41K | $3.83M |
| Current Income Tax Payable | $0 | $960K | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Current Unearned Revenue | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $2.35M | $0 | $0 | $36K | $0 |
| Other Current Liabilities | $203.28M | $36.51M | $76.45M | $17.18M | $4.05M | $0 | $0 | $0 | $444K | $0 | $0 | $100K | $0 |
| Total Current Liabilities | $378.84M | $230.1M | $138.85M | $96.56M | $23.07M | $23.44M | $24.49M | $10.82M | $12.18M | $7.17M | $2.63M | $973K | $4.13M |
| Long-Term Liabilities | |||||||||||||
| Long-Term Debt | $140.93M | $180.71M | $178.07M | $94.26M | $49.09M | $48.32M | $17.33M | $3.62M | $6.66M | $9.47M | $0 | $4.44M | $0 |
| Long-Term Unearned Revenue | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Long-Term Deferred Tax Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Long-Term Liabilities | $54.36M | $91.68M | $73.3M | $31.1M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $575K | $0 |
| Total Long-Term Liabilities | $222.67M | $281.38M | $258.4M | $125.36M | $49.09M | $48.9M | $17.33M | $3.62M | $6.66M | $9.47M | $0 | $5.02M | $0 |
| Other Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities | $601.51M | $511.48M | $397.26M | $221.92M | $72.15M | $72.34M | $41.83M | $14.44M | $18.84M | $16.64M | $2.63M | $5.99M | $4.13M |
| Stockholders' Equity | |||||||||||||
| Preferred Stock | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $5K |
| Common Stock | $5K | $5K | $5K | $4K | $4K | $4K | $4K | $3K | $3K | $2K | $2K | $1K | $769 |
| Retained Earnings | -$1.31B | -$1.12B | -$835.57M | -$596.33M | -$409.2M | -$278.8M | -$175.9M | -$107.55M | -$76.58M | -$47.64M | -$20.44M | -$8.23M | -$2.23M |
| Comprehensive Income & Other | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | -$5K |
| Other Stockholders' Equity | $1.39B | $1.18B | $1.03B | $705.88M | $424.83M | $392.59M | $354.61M | $108.49M | $93.3M | $69.21M | $66.88M | $5.03M | $200K |
| Total Equity | $88.3M | $57.02M | $190.98M | $109.56M | $15.63M | $113.79M | $178.72M | $938K | $16.72M | $21.57M | $46.44M | -$3.2M | -$2.03M |
| Minority Interest | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities and Equity | $689.8M | $568.5M | $588.24M | $331.48M | $87.79M | $186.13M | $220.55M | $15.38M | $35.56M | $38.21M | $49.08M | $2.79M | $2.1M |
| Supplementary Data | |||||||||||||
| Total Debt | $241.29M | $192.96M | $186.37M | $94.68M | $49.71M | $50.12M | $19.93M | $6.91M | $9.93M | $9.74M | $0 | $4.48M | $3.83M |
| Net Debt | -$81.64M | -$122.4M | -$199.82M | -$106.16M | -$36.76M | -$133.75M | -$200.03M | -$7.06M | -$24.09M | -$26.88M | -$48.04M | $1.87M | $1.74M |
Cash Flow Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 | FY 2014 | FY 2013 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 | 2014-12-31 | 2013-12-31 |
| Operating Activities | |||||||||||||
| Net Income | -$183.17M | -$287.22M | -$239.24M | -$187.13M | -$130.4M | -$102.9M | -$68.35M | -$30.97M | -$28.94M | -$27.2M | -$10.56M | -$6M | -$2.17M |
| Depreciation & Amortization | $9.06M | $7.96M | $6.83M | $4.4M | $76K | $78K | $37K | $49K | $43K | $20K | $4K | $5.49M | $1.84M |
| Deferred Income Tax | $0 | $0 | $0 | $0 | $0 | $1.25M | $0 | -$2.79M | $646K | $0 | $2.28M | $0 | $0 |
| Stock-Based Compensation | $93.75M | $85.22M | $62.62M | $37.73M | $20.8M | $14.76M | $6.12M | $1.75M | $2.07M | $2.03M | $803K | $377K | $55K |
| Changes in Working Capital: | |||||||||||||
| Accounts Receivable | -$82.46M | -$47.18M | -$57.12M | -$37.7M | $0 | $178K | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Inventory | -$15.67M | -$2.44M | -$8.16M | -$5.28M | -$6K | -$178K | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Accounts Payable | -$6.46M | $31.32M | $2.07M | $25.46M | -$355K | $2.56M | $7.26M | $252K | -$646K | $2.19M | $1.13M | $599K | $158K |
| Other Working Capital | $82.07M | $52.2M | $34.81M | $41.19M | $685K | -$2.15M | $7.91M | $1.27M | -$114K | $1.61M | -$196K | -$84K | -$5K |
| Total Working Capital Change | -$22.52M | $33.9M | -$28.39M | $23.67M | $324K | $412K | $15.17M | $1.52M | -$760K | $3.8M | $938K | $515K | $153K |
| Other Non-Cash Items | $9.48M | $31.73M | $53.1M | $4.83M | $974K | $7.95M | $650K | $376K | $471K | $69K | -$902K | -$4.98M | -$1.51M |
| Net Cash from Operating | -$93.41M | -$128.41M | -$145.08M | -$116.51M | -$108.23M | -$78.46M | -$46.38M | -$30.05M | -$26.47M | -$21.28M | -$7.44M | -$4.6M | -$1.63M |
| Investing Activities | |||||||||||||
| Capital Expenditures | -$480K | -$270K | -$582K | -$702K | -$308K | -$46K | -$16K | -$33K | -$10K | -$105K | -$20K | $0 | $0 |
| Acquisitions | $0 | $0 | $0 | -$53M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Purchases of Investments | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Sales of Investments | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Investing Activities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Net Cash from Investing | -$480K | -$270K | -$582K | -$53.7M | -$308K | -$46K | -$16K | -$33K | -$10K | -$105K | -$20K | $0 | $0 |
| Financing Activities | |||||||||||||
| Debt Repaid | $7.75M | $990K | -$85M | -$45M | - | -$28.34M | -$12.76M | $3.33M | $278K | -$10M | -$7.34M | -$5.19M | -$3.78M |
| Common Stock Issuance | $126.27M | $40.78M | $258.75M | $243.76M | $7.44M | $14.13M | $238.23M | $12.88M | $23.68M | $33K | $45.55M | $0 | $0 |
| Common Stock Repurchases | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Dividends Paid | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Financing Activities | -$17.05M | $18.05M | -$12.74M | -$4.18M | $3.69M | -$53K | $1.39M | $486K | $485K | -$65K | -$12K | -$63K | -$58K |
| Net Cash from Financing | $101.47M | $57.84M | $331.01M | $284.58M | $11.13M | $42.41M | $252.39M | $10.03M | $23.88M | $9.97M | $52.88M | $5.13M | $3.72M |
| Forex Effect | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | $7.58M | -$70.84M | $185.35M | $114.37M | -$97.4M | -$36.09M | $206M | -$20.05M | -$2.6M | -$11.42M | $45.42M | $530K | $2.09M |
| Supplementary Data | |||||||||||||
| Operating Cash Flow | -$93.41M | -$128.41M | -$145.08M | -$116.51M | -$108.23M | -$78.46M | -$46.38M | -$30.05M | -$26.47M | -$21.28M | -$7.44M | -$4.6M | -$1.63M |
| Capital Expenditure | -$480K | -$270K | -$582K | -$702K | -$308K | -$46K | -$16K | -$33K | -$10K | -$105K | -$20K | $0 | $0 |
| Free Cash Flow | -$93.89M | -$128.68M | -$145.66M | -$117.21M | -$108.53M | -$78.5M | -$46.39M | -$30.09M | -$26.48M | -$21.39M | -$7.46M | -$4.6M | -$1.63M |
| Cash at Beginning | $315.35M | $386.19M | $200.84M | $86.47M | $183.88M | $219.97M | $13.97M | $34.02M | $36.62M | $48.04M | $2.62M | $2.09M | $2K |
| Cash at End | $322.93M | $315.35M | $386.19M | $200.84M | $86.47M | $183.88M | $219.97M | $13.97M | $34.02M | $36.62M | $48.04M | $2.62M | $2.09M |