Skip to main content
Signal8

Biodexa Pharmaceuticals Plc (BDRX)

Biodexa Pharmaceuticals Plc, a biopharmaceutical company in the clinical development stage, is dedicated to advancing a diverse portfolio of products. Founded in 2000 and headquartered in Cardiff, United Kingdom, the company was formerly known as Midatech Pharma plc until its rebranding in March 2023. Its research and development efforts are focused on addressing significant unmet medical needs, including familial adenomatous polyposis, non-muscle invasive bladder cancer, Type 1 diabetes, and a spectrum of rare or orphan brain cancers. The company's primary drug candidate, Tolimidone, a selective activator of the lyn kinase enzyme, is currently undergoing Phase II clinical trials for the management of Type 1 diabetes. Additionally, Biodexa is progressing MTX110 through Phase I studies as an investigational treatment targeting specific challenging brain malignancies such as diffuse intrinsic recurrent glioblastoma, diffuse midline glioma, and medulloblastoma. Beyond its direct drug pipeline, Biodexa Pharmaceuticals also provides a suite of advanced drug delivery platforms designed to optimize therapeutic efficacy. These include Q-Sphera, a microtechnology utilizing polymer microspheres for controlled, sustained release of medications; MidaSolve, an oligosaccharide nanotechnology that facilitates the solubilization of drugs, enabling their direct and localized administration into tumor sites; and MidaCore, which employs gold nanoparticles for precise targeting of diseased areas, allowing for the delivery of either chemotherapeutic or immunotherapeutic agents. The company has established strategic collaboration agreements with pharmaceutical industry leaders Janssen and Melior.

Sector: Pharmaceutical Preparations

Industry: Biotechnology

Biodexa Pharmaceuticals Plc logo

Biodexa Pharmaceuticals Plc

NASDAQ:BDRXHealthcare
-12.05%$3.43
AH$3.15-8.16%vs close
Mkt Cap$3.53M
Float249K
O/S1.03M
Vol
$ Vol
RVOL
Inst Own-
Earnings
Dilution
Pipeline3 lead-sponsored trials·0 active0 completed(5 more as collaborator)

Trials need funding. See this company's dilution risk and cash position.

Clinical Trials
Sponsor role
Status
Phase
  • Phase 4
    Terminated

    Gelclair at Conditioning or After Oral Mucositis Diagnosed vs. Magic Mouth Wash in Stem Cell Transplant Recipients

    Gelclair, First® Mouthwash BLM

    Oral Mucositis

    Enrollment
    28
    Start
    May 2018
    Primary Completion
    Nov 2019
    Completion
    Nov 2019
    NCT03490396
  • Phase 1
    Terminated

    A Study of Intra-tumoral Administered MTX110 in Patients With Recurrent Glioblastoma

    MTX110

    Recurrent Glioblastoma

    Enrollment
    4
    Start
    Oct 2022
    Primary Completion
    Sep 2024
    Completion
    Sep 2024
    NCT05324501
  • Expanded access
    Available

    Expanded Access to 0.5 mg eRapa for Familial Adenomatous Polyposis

    eRapa (encapsulated rapamycin)

    Familial Adenomatous Polyposis (FAP)

    Enrollment
    -
    Start
    -
    Primary Completion
    -
    Completion
    -
    NCT07689942