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Beam Therapeutics Inc. (BEAM)

Beam Therapeutics Inc., founded in 2017 and based in Cambridge, Massachusetts, operates as a pioneering biopharmaceutical firm. Its core mission involves engineering precise genetic remedies to tackle a spectrum of severe human ailments, primarily within the United States. The company's developmental portfolio features several key candidates: BEAM-101 is being advanced to treat both sickle cell disease and beta thalassemia. BEAM-102 is specifically designed for addressing sickle cell disease. BEAM-201, an allogeneic chimeric antigen receptor T-cell therapy, is under investigation for individuals suffering from relapsed or refractory T-cell acute lymphoblastic leukemia. BEAM-301 is a liver-targeted candidate aimed at patients afflicted with Glycogen Storage Disease Type Ia. Beyond these flagship programs, Beam Therapeutics is also engaged in devising treatments for alpha-1 antitrypsin deficiency, various ocular conditions, and other disorders impacting the liver, muscular system, and central nervous system. To further its research and development objectives, Beam Therapeutics has forged numerous strategic alliances and partnerships. These include collaborations with Boston Children's Hospital; a research and clinical trial agreement with Magenta Therapeutics, Inc.; a licensing deal with Sana Biotechnology, Inc.; and a research partnership with the Institute of Molecular and Clinical Ophthalmology Basel. Additionally, the company maintains research collaborations with both Pfizer Inc. and Apellis Pharmaceuticals, Inc., alongside a comprehensive collaboration and license agreement with Verve Therapeutics, Inc.

Sector: Biological Products, (No Diagnostic Substances)

Industry: Biotechnology

Beam Therapeutics Inc. logo

Beam Therapeutics Inc.

NASDAQ:BEAMHealthcare
-5.58%$27.23
AH$27.71+1.76%vs close
Mkt Cap$2.81B
Float81.98M
O/S103.29M
Vol
$ Vol
RVOL
Inst Own-
SI32.0%
Earnings
Dilution
Phase Distribution
8 lead-sponsored trials·6 active·2 completed
Phase 11
Phase 1/24
Not applicable3
(2 more as collaborator)
Status Overview
Recruiting4
Active, not recruiting2
Completed2

Trials need funding. See this company's dilution risk and cash position.

Clinical Trials
Sponsor role
Status
Phase
  • Phase 1/2
    Active, not recruiting

    BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease

    BEAM-101

    Sickle Cell Disease

    Enrollment
    15
    Start
    Aug 2022
    Primary Completion
    Feb 2028est.
    Completion
    Feb 2028est.
    NCT05456880
  • Phase 1/2
    Active, not recruiting

    A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL)

    BEAM-201

    Lymphoblastic Lymphoma, T-Cell Lymphoblastic Leukemia/Lymphoma +1

    Enrollment
    5
    Start
    May 2023
    Primary Completion
    Dec 2026est.
    Completion
    Dec 2026est.
    NCT05885464
  • Phase 1/2
    Recruiting

    A Study to Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD)

    BEAM-302

    Alpha 1-Antitrypsin Deficiency

    Enrollment
    192
    Start
    Jun 2024
    Primary Completion
    May 2028est.
    Completion
    May 2030est.
    NCT06389877
  • Phase 1/2
    Recruiting

    A Phase 1/2, Dose-Exploration Study to Evaluate the Safety and Efficacy of BEAM-301 in Patients With Glycogen Storage Disease Type Ia (GSDIa)

    BEAM-301: Single dose of BEAM-301 administered by IV

    Glycogen Storage Disease Type Ia

    Enrollment
    36
    Start
    Dec 2024
    Primary Completion
    Dec 2027est.
    Completion
    Dec 2027est.
    NCT06735755
  • Phase 1
    Recruiting

    This is a Phase 1, Randomized, Single-blind, Placebo-controlled Study to Assess the Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of BEAM-103 in Healthy Subjects

    BEAM-103, Placebo Comparator

    Healthy Subjects, Healthy Participant Study

    Enrollment
    30
    Start
    Oct 2025
    Primary Completion
    Jan 2026est.
    Completion
    May 2026est.
    NCT07304791
  • Not applicable
    Completed

    An Exploratory Investigation of a Supplement to Enhance Sleep Quality and Quantity

    Beam Organics Dream Powder, Beam Organics Dream Powder Extra Strength

    Sleep, Sleep Disturbance +1

    Enrollment
    64
    Start
    May 2022
    Primary Completion
    Sep 2022
    Completion
    Sep 2022
    NCT05521243
  • Not applicable
    Completed

    A Crossover Trial to Examine the Efficacy of a Powder to Improve Sleep Quality and Performance

    BEAM Dream Powder, Placebo Control

    Sleep, Sleep Disorder

    Enrollment
    40
    Start
    Jul 2024
    Primary Completion
    Oct 2024
    Completion
    Oct 2024
    NCT07183735
  • Observational
    Recruiting

    A Long-term Follow-up Study in Patients Who Received BEAM-101

    Long-Term Follow-up Study of patients who received BEAM-101

    Hemoglobinopathy, Sickle Cell Disease

    Enrollment
    50
    Start
    Dec 2025
    Primary Completion
    Feb 2043est.
    Completion
    Feb 2043est.
    NCT07373639