CRESCENT BIOPHARMA, INC. (CBIO)
Crescent Biopharma, Inc. is a biotechnology firm dedicated to the research and development of novel cancer therapies. Its investigational portfolio notably includes CR-001, a proprietary bispecific antibody engineered to simultaneously target PD-1 and VEGF pathways for the treatment of solid tumors. The company's pipeline further comprises CR-002 and CR-003. Crescent Biopharma also maintains a strategic alliance with Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd., focusing on the joint advancement and commercialization of oncology therapeutics, encompassing innovative combination approaches. The company's operations are headquartered in Waltham, Massachusetts.
Sector: Pharmaceutical Preparations
Industry: Biotechnology
Crescent Biopharma, Inc.
NASDAQ:CBIOHealthcare · Biotechnology
-4.19%$13.48
AH$13.67+1.41%vs close
Mkt Cap$500.74M
Float20.86M
O/S37.15M
Vol
$ Vol
RVOL
Inst Own79.5%
SI21.2%
Earnings
Dilution
Financials Summary
Revenue$10.84M
Net Income-$153.94M
Total Assets$240.29M
Free Cash Flow-$144.45M
Debt & Equity
Debt 1%
Equity 97%
Preferred 2%
Total Debt$1.64M
Total Equity$203.01M
Preferred Stock$4M
Shares Outstanding
Short Interest
Split History2 splits · 2 reverse
- 1:15Reverse splitOct 31, 202315 shares → 1
- 1:15Reverse splitFeb 6, 200615 shares → 1
Balance Sheet Details
Assets$240.29M
Liabilities$37.28M
Accounts Receivable$18M
Accounts Payable$10M
Inventory$0
PP&E (Net)$2.31M
Goodwill$0
Intangible Assets$0
Income Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 | FY 2014 | FY 2013 | FY 2012 | FY 2011 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 | 2014-12-31 | 2013-12-31 | 2012-12-31 | 2011-12-31 |
| Revenue | $10.84M | $0 | $10K | $75K | $1.16M | $10.16M | $0 | $0 | $0 | $19K | $20.07M | $15.03M | $3.99M | $15.26M | $3.81M |
| YoY Growth | - | - | -86.7% | -93.5% | -88.6% | - | - | - | - | -99.9% | 33.6% | 276.4% | -73.8% | 300.0% | - |
| Cost of Revenue | $0 | $0 | $0 | $0 | $0 | $0 | $899K | $275K | $264K | $0 | $0 | $0 | $0 | $0 | $0 |
| Gross Profit | $10.84M | $0 | $10K | $75K | $1.16M | $10.16M | -$899K | -$275K | -$264K | $0 | $20.07M | $15.03M | $3.99M | $15.26M | $0 |
| Gross Margin | 100.0% | - | 100.0% | 100.0% | 100.0% | 100.0% | - | - | - | - | 100.0% | 100.0% | 100.0% | 100.0% | - |
| Research and Development | $138.09M | $28.06M | $20.07M | $28.39M | $47.49M | $44.93M | $47.03M | $40.09M | $24.1M | $23.28M | $25.05M | $19.57M | $11.7M | $9.44M | $7.8M |
| Selling, General, and Administrative | $25.39M | $16.32M | $19.21M | $19.09M | $17.12M | $16.74M | $14.36M | $11.41M | $9.83M | $8.65M | $7.81M | $6.6M | $2.9M | $2.18M | $2.1M |
| Other | $0 | $5.51M | $637 | $443 | $0 | $0 | $0 | $0 | -$264K | $0 | $0 | -$262 | -$1K | -$78 | $0 |
| Total Operating Expenses | $163.48M | $49.9M | $39.29M | $47.48M | $64.61M | $61.67M | $61.39M | $51.51M | $33.67M | $31.93M | $32.86M | $26.17M | $14.6M | $11.62M | $9.9M |
| Operating Income (EBIT) | -$152.63M | -$49.9M | -$39.28M | -$47.4M | -$63.45M | -$51.51M | -$61.39M | -$51.51M | -$33.93M | -$31.91M | -$12.78M | -$11.14M | -$10.61M | $3.64M | -$6.08M |
| Operating Margin | -1407.5% | - | -392752.9% | -63204.4% | -5470.7% | -506.8% | - | - | - | -172505.3% | -63.7% | -74.1% | -265.7% | 23.8% | -159.5% |
| Interest Expense | $2.19M | $852K | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Interest Income | $2.88M | $1M | $2.38M | $715K | $20K | $482K | $3.5M | $3.23M | $651K | $104K | $0 | $0 | $0 | $0 | $0 |
| Other Income (Expense) | $690K | $1.37M | $2.38M | $715K | $20K | $482K | $3.5M | $3.23M | $651K | $104K | $15K | $18K | -$132 | $21K | -$28K |
| Income Before Tax (EBT) | -$151.94M | -$48.52M | -$36.9M | -$46.69M | -$63.43M | -$51.03M | -$57.89M | -$48.27M | -$33.28M | -$31.81M | -$12.77M | -$11.12M | -$10.61M | $3.66M | -$6.11M |
| Income Tax Expense | $2M | $0 | $0 | $0 | $0 | $0 | -$3.78M | $3.23M | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Net Income | -$153.94M | -$48.52M | -$36.9M | -$46.69M | -$63.43M | -$51.03M | -$54.12M | -$48.27M | -$33.28M | -$31.81M | -$12.77M | -$11.12M | -$10.61M | $3.66M | -$6.11M |
| Net Income Margin | -1419.6% | - | -368994.2% | -62251.7% | -5469.0% | -502.1% | - | - | - | -171945.1% | -63.6% | -74.0% | -265.6% | 24.0% | -160.3% |
| Supplementary Data | |||||||||||||||
| EPS | -14.78 | -63.22 | -58.25 | -88.88 | -123.27 | -111.60 | -133.84 | -117.61 | -113.22 | -149.65 | -67.17 | -60.27 | -199.32 | 305.64 | -32.55 |
| Diluted EPS | -14.78 | -63.22 | -58.25 | -88.88 | -123.27 | -111.60 | -133.84 | -117.61 | -113.22 | -149.65 | -67.17 | -60.27 | -199.32 | 305.64 | -32.55 |
| Weighted Average OS | 10.41M | 767,580 | 633,424 | 525,311 | 514,532 | 457,211 | 432,547 | 410,446 | 293,957 | 212,563 | 190,105 | 184,522 | 53,209 | 11,962 | 187,819 |
| EBITDA | -$149.67M | -$44.17M | -$39.12M | -$47.2M | -$63.18M | -$51.24M | -$56.99M | -$51.23M | -$33.67M | -$31.72M | -$12.59M | -$10.98M | -$10.47M | $3.73M | -$6M |
| EBITDA Margin | -1380.2% | - | -391213.5% | -62927.6% | -5447.9% | -504.2% | - | - | - | -171475.4% | -62.7% | -73.1% | -262.3% | 24.5% | -157.3% |
Balance Sheet
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 | FY 2014 | FY 2013 | FY 2012 | FY 2011 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 | 2014-12-31 | 2013-12-31 | 2012-12-31 | 2011-12-31 |
| Assets | |||||||||||||||
| Current Assets | |||||||||||||||
| Cash and Cash Equivalents | $213.19M | $34.77M | $41.79M | $47.87M | $90.25M | $137.04M | $158.2M | $209.92M | $123.92M | $40.04M | $46.8M | $55.2M | $2.31M | $17.37M | $28.17M |
| Short-Term Investments | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $11K | $9K | $16K | $1K | $17.37M | $28.17M |
| Cash and Short-Term Investments | $213.19M | $34.77M | $41.79M | $47.87M | $90.25M | $137.04M | $158.2M | $209.92M | $123.92M | $40.04M | $46.8M | $55.2M | $2.31M | $17.37M | $28.17M |
| Accounts Receivable | $18M | $0 | $176K | $144K | $1K | $2K | $186K | $413K | $102K | $269K | $39K | $22K | $95K | $0 | $0 |
| Inventory | $0 | $0 | $0 | $0 | $0 | $0 | $0 | -$405 | $0 | $199K | $0 | -$77 | $0 | $0 | $0 |
| Other Current Assets | $1.28M | $38K | $0 | $0 | $0 | $0 | $0 | $0 | $0 | -$199K | $9K | $58K | $2.31M | $0 | $0 |
| Total Current Assets | $236.66M | $34.8M | $43.79M | $50.71M | $90.79M | $138.27M | $162.53M | $212.27M | $127.22M | $40.52M | $47.24M | $56.12M | $4.88M | $17.97M | $28.37M |
| Long-Term Assets | |||||||||||||||
| Property, Plant & Equipment Net | $2.31M | $0 | $768K | $751K | $1.95M | $2.95M | $3.83M | $957K | $1.11M | $1.06M | $521K | $452K | $400K | $451K | $235K |
| Goodwill | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Intangible Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Long-Term Investments | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Deferred Tax Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Long-Term Assets | $1.32M | $813K | $758K | $345K | $1.61M | $1.61M | $1.61M | $1.61M | $257K | $812K | $697K | $697K | $0 | $0 | $309K |
| Total Long-Term Assets | $3.64M | $813K | $1.53M | $1.1M | $3.56M | $4.56M | $5.44M | $2.57M | $1.36M | $1.87M | $1.22M | $1.15M | $400K | $451K | $543K |
| Other Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | -$272 | $0 | -$327 | -$279 | $27 | $0 | $0 | $0 |
| Total Assets | $240.29M | $35.62M | $45.32M | $51.81M | $94.35M | $142.83M | $167.97M | $214.84M | $128.58M | $42.39M | $48.46M | $57.26M | $5.28M | $18.42M | $28.91M |
| Liabilities | |||||||||||||||
| Current Liabilities | |||||||||||||||
| Accounts Payable | $10M | $107K | $868K | $970K | $2.11M | $2.09M | $1.44M | $2.66M | $2.65M | $1.57M | $564K | $874K | $1.14M | $764K | $536K |
| Short-Term Debt | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Current Income Tax Payable | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Current Unearned Revenue | $4.16M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $69K | $0 | $0 | $0 | $3.99M | $15M |
| Other Current Liabilities | $10.12M | $76K | $2.96M | $2.97M | $2.5M | $3.91M | $3.03M | $99K | $78K | $0 | $0 | $97K | $104K | $92K | $635K |
| Total Current Liabilities | $36.07M | $9.61M | $6.84M | $8.88M | $11.82M | $12.43M | $10.95M | $8.76M | $8.17M | $6.33M | $7.75M | $6.46M | $2.28M | $5.69M | $16.41M |
| Long-Term Liabilities | |||||||||||||||
| Long-Term Debt | $0 | $37.48M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Long-Term Unearned Revenue | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $97K | $200K | $4.04M |
| Long-Term Deferred Tax Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Long-Term Liabilities | $0 | $4M | $0 | $0 | $0 | $264K | $0 | $612K | $707K | $754K | $244K | $0 | $97K | $0 | $0 |
| Total Long-Term Liabilities | $1.21M | $41.48M | $67K | $0 | $919K | $2.18M | $2.82M | $612K | $707K | $754K | $244K | $0 | $97K | $200K | $4.04M |
| Other Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $223 | $0 | -$196 | -$625 | $0 | $0 | $0 | $0 |
| Total Liabilities | $37.28M | $51.1M | $6.9M | $8.88M | $12.74M | $14.61M | $13.77M | $9.38M | $8.88M | $7.09M | $7.99M | $6.46M | $2.38M | $5.89M | $20.45M |
| Stockholders' Equity | |||||||||||||||
| Preferred Stock | $4M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $346 | $0 | $31K | $31K | $31K |
| Common Stock | $28K | $1K | $64K | $54K | $52K | $49K | $43K | $43K | $34K | $23K | $19K | $19K | $1K | $930 | $930 |
| Retained Earnings | -$171.81M | -$17.87M | -$456.49M | -$419.59M | -$372.9M | -$309.47M | -$258.44M | -$200.55M | -$152.28M | -$118.98M | -$87.17M | -$74.4M | -$63.28M | -$52.67M | -$56.33M |
| Comprehensive Income & Other | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Stockholders' Equity | $374.79M | $2.39M | $494.84M | $462.46M | $454.45M | $437.64M | $412.6M | $405.97M | $271.94M | $154.25M | $127.62M | $125.18M | $66.18M | $65.2M | $64.78M |
| Total Equity | $203.01M | -$15.48M | $38.41M | $42.93M | $81.6M | $128.22M | $154.2M | $205.46M | $119.7M | $35.3M | $40.47M | $50.8M | $2.91M | $12.53M | $8.46M |
| Minority Interest | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities and Equity | $240.29M | $35.62M | $45.32M | $51.81M | $94.35M | $142.83M | $167.97M | $214.84M | $128.58M | $42.39M | $48.46M | $57.26M | $5.28M | $18.42M | $28.91M |
| Supplementary Data | |||||||||||||||
| Total Debt | $1.64M | $37.48M | $808K | $919K | $1.92M | $2.82M | $3.62M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Net Debt | -$211.55M | $2.72M | -$40.98M | -$46.95M | -$88.33M | -$134.22M | -$154.58M | -$209.92M | -$123.92M | -$40.04M | -$46.8M | -$55.2M | -$2.31M | -$17.37M | -$28.17M |
Cash Flow Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 | FY 2014 | FY 2013 | FY 2012 | FY 2011 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 | 2014-12-31 | 2013-12-31 | 2012-12-31 | 2011-12-31 |
| Operating Activities | |||||||||||||||
| Net Income | -$153.94M | -$37.88M | -$36.9M | -$46.69M | -$63.43M | -$51.03M | -$57.89M | -$48.27M | -$33.28M | -$31.81M | -$12.77M | -$11.12M | -$10.61M | $3.66M | -$6.11M |
| Depreciation & Amortization | $84K | $35K | $153K | $207K | $265K | $271K | $899K | $275K | $264K | $191K | $191K | $159K | $133K | $100K | $84K |
| Deferred Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | -$2.96M | -$2.32M | $0 | -$426K | -$415K | $0 |
| Stock-Based Compensation | $13.3M | $4.77M | $3.56M | $3.86M | $6.09M | $6.9M | $6.22M | $4.59M | $3.76M | $2.96M | $2.32M | $1.64M | $426K | $415K | $376K |
| Changes in Working Capital: | |||||||||||||||
| Accounts Receivable | -$18M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $187K | $0 | $0 |
| Inventory | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Accounts Payable | $2.08M | -$539K | -$102K | -$1.14M | $18K | $654K | -$1.23M | $16K | $1.06M | $1M | -$310K | -$271K | $381K | $229K | $83K |
| Other Working Capital | $2.55M | $1.7M | -$2.46M | -$3.52M | -$1.18M | $3.28M | $21K | $64K | -$1.57M | -$2.08M | $2.31M | $5.32M | -$6.06M | -$14.87M | $19.42M |
| Total Working Capital Change | -$13.37M | $1.16M | -$2.56M | -$4.66M | -$1.17M | $3.93M | -$1.21M | $80K | -$512K | -$1.08M | $2M | $5.04M | -$5.49M | -$14.64M | $19.51M |
| Other Non-Cash Items | $82.4M | $814K | $865K | $829K | $751K | $681K | $0 | $168 | $0 | $2.96M | $2.32M | $1K | $426K | $415K | $0 |
| Net Cash from Operating | -$71.53M | -$31.1M | -$34.88M | -$46.46M | -$57.49M | -$39.24M | -$51.98M | -$43.33M | -$29.77M | -$29.73M | -$8.24M | -$4.28M | -$15.54M | -$10.47M | $13.85M |
| Investing Activities | |||||||||||||||
| Capital Expenditures | -$919K | -$10K | -$21K | -$84K | -$15K | -$69K | -$145K | -$126K | -$294K | -$704K | -$269K | -$213K | -$82K | -$316K | -$182K |
| Acquisitions | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Purchases of Investments | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Sales of Investments | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Investing Activities | -$72M | $30K | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | -$10K | -$58K |
| Net Cash from Investing | -$72.92M | $20K | -$21K | -$84K | -$15K | -$69K | -$145K | -$126K | -$294K | -$704K | -$269K | -$213K | -$82K | -$326K | -$240K |
| Financing Activities | |||||||||||||||
| Debt Repaid | - | - | - | - | - | - | - | - | - | - | - | - | - | - | $24K |
| Common Stock Issuance | $321.89M | $0 | $28.71M | $4.16M | $10.7M | $17.82M | $413K | $128.43M | $113.57M | $23.6M | $114K | $57.25M | $559K | $237 | $3 |
| Common Stock Repurchases | -$177K | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Dividends Paid | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Financing Activities | $1.27M | $5K | $116K | $0 | $25K | $319K | $0 | $1.02M | $373K | $73K | $0 | $134K | $0 | $0 | $0 |
| Net Cash from Financing | $322.98M | $5K | $28.82M | $4.16M | $10.72M | $18.14M | $413K | $129.45M | $113.95M | $23.67M | $114K | $57.38M | $559K | $237 | -$24K |
| Forex Effect | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | $178.53M | -$31.07M | -$6.08M | -$42.38M | -$46.78M | -$21.17M | -$51.72M | $85.99M | $83.88M | -$6.76M | -$8.4M | $52.89M | -$15.06M | -$10.8M | $13.59M |
| Supplementary Data | |||||||||||||||
| Operating Cash Flow | -$71.53M | -$31.1M | -$34.88M | -$46.46M | -$57.49M | -$39.24M | -$51.98M | -$43.33M | -$29.77M | -$29.73M | -$8.24M | -$4.28M | -$15.54M | -$10.47M | $13.85M |
| Capital Expenditure | -$72.92M | -$10K | -$21K | -$84K | -$15K | -$69K | -$145K | -$126K | -$294K | -$704K | -$269K | -$213K | -$82K | -$316K | -$182K |
| Free Cash Flow | -$144.45M | -$31.11M | -$34.9M | -$46.54M | -$57.5M | -$39.31M | -$52.13M | -$43.46M | -$30.06M | -$30.44M | -$8.51M | -$4.49M | -$15.62M | -$10.79M | $13.67M |
| Cash at Beginning | $34.77M | $41.79M | $47.87M | $90.25M | $137.04M | $158.2M | $209.92M | $123.92M | $40.04M | $46.8M | $55.2M | $2.31M | $17.37M | $28.17M | $14.58M |
| Cash at End | $213.3M | $10.72M | $41.79M | $47.87M | $90.25M | $137.04M | $158.2M | $209.92M | $123.92M | $40.04M | $46.8M | $55.2M | $2.31M | $17.37M | $28.17M |