C4 Therapeutics, Inc. (CCCC)
C4 Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing innovative therapeutic candidates. Its core strategy involves degrading proteins implicated in disease, addressing a range of conditions including cancer, neurodegenerative disorders, and other illnesses. The company's primary drug candidate, CFT7455, is an orally administered MonoDAC degrader of the IKZF1 and IKZF3 proteins. This compound is currently undergoing Phase 1/2 clinical trials for the treatment of multiple myeloma and various non-Hodgkin lymphomas, such as peripheral T-cell lymphoma and mantle cell lymphoma. Additionally, C4 Therapeutics is advancing several other programs: CFT8634, an orally bioavailable BiDAC degrader targeting the BRD9 protein, for potential use in synovial sarcoma and SMARCB1-deleted solid tumors. CFT1946, an orally administered BiDAC degrader designed to act on the V600X mutant BRAF, aimed at indications like melanoma, non-small cell lung cancer (NSCLC), colorectal cancer, and other solid malignancies. CFT8919, an orally available, allosteric, and mutant-selective BiDAC degrader specifically targeting epidermal growth factor receptor (EGFR) with an L858R mutation in NSCLC. Their early-stage pipeline also features RET degraders for various forms of cancer. C4 Therapeutics, Inc. has formed strategic partnerships with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc., Biogen MA, Inc., and Calico Life Sciences LLC. The company was established in 2015 and its headquarters are located in Watertown, Massachusetts.
Sector: Biological Products, (No Diagnostic Substances)
Industry: Biotechnology
C4 Therapeutics, Inc.
NASDAQ:CCCCHealthcare · Biotechnology
+2.12%$3.37
AH$3.28-2.77%vs close
Mkt Cap$414.59M
Float98.54M
O/S123.03M
Vol
$ Vol
RVOL
Inst Own96.4%
Earnings
Dilution
Financials Summary
Revenue$35.95M
Net Income-$104.99M
Total Assets$359.07M
Free Cash Flow-$99.3M
Debt & Equity
Debt 19%
Equity 81%
Total Debt$59.98M
Total Equity$256.59M
Shares Outstanding
Short Interest
Split History
No splits on record
Nothing in CCCC's public trading history: no forward or reverse split has affected the share count.
Balance Sheet Details
Assets$359.07M
Liabilities$102.49M
Accounts Receivable$2.4M
Accounts Payable$858K
Inventory$0
PP&E (Net)$45.28M
Goodwill$0
Intangible Assets$0
Income Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 |
|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Revenue | $35.95M | $35.58M | $20.76M | $31.1M | $45.78M | $33.2M | $21.38M | $19.36M |
| YoY Growth | 1.0% | 71.4% | -33.3% | -32.1% | 37.9% | 55.3% | 10.4% | - |
| Cost of Revenue | $7.97M | $0 | $7.74M | $0 | $0 | $78.44M | $0 | $28.59M |
| Gross Profit | $27.97M | $35.58M | $13.02M | $31.1M | $45.78M | -$45.24M | $21.38M | -$9.23M |
| Gross Margin | 77.8% | 100.0% | 62.7% | 100.0% | 100.0% | -136.3% | 100.0% | -47.7% |
| Research and Development | $104.24M | $110.64M | $117.71M | $117.84M | $94.67M | $78.44M | $48.06M | $28.59M |
| Selling, General, and Administrative | $36.2M | $42.12M | $42.08M | $42.79M | $33.25M | $15.2M | $8.77M | $7.16M |
| Other | -$7.97M | $2.44M | -$7.74M | $0 | $0 | -$78.44M | $0 | -$7K |
| Total Operating Expenses | $132.46M | $155.2M | $152.05M | $160.63M | $127.92M | $15.2M | $56.83M | $35.75M |
| Operating Income (EBIT) | -$104.49M | -$119.61M | -$139.03M | -$129.53M | -$82.13M | -$60.45M | -$35.45M | -$16.39M |
| Operating Margin | -290.7% | -336.1% | -669.8% | -416.6% | -179.4% | -182.1% | -165.8% | -84.6% |
| Interest Expense | $0 | $0 | $1.37M | $2.22M | $2.15M | $1.23M | $0 | $0 |
| Interest Income | $10.35M | $14.43M | $9.81M | $3.58M | $387K | $393K | $1.83M | $685K |
| Other Income (Expense) | -$384K | $14.43M | $7.82M | $1.36M | -$1.76M | -$5.26M | $2.16M | $678K |
| Income Before Tax (EBT) | -$104.87M | -$105.19M | -$131.21M | -$128.18M | -$83.89M | -$65.71M | -$33.3M | -$15.71M |
| Income Tax Expense | $121K | $131K | $1.28M | $0 | $0 | $626K | $804K | $0 |
| Net Income | -$104.99M | -$105.32M | -$132.49M | -$128.18M | -$83.89M | -$66.33M | -$34.1M | -$15.71M |
| Net Income Margin | -292.1% | -296.0% | -638.3% | -412.2% | -183.2% | -199.8% | -159.5% | -81.1% |
| Supplementary Data | ||||||||
| EPS | -1.27 | -1.52 | -2.67 | -2.62 | -1.82 | -1.54 | -0.79 | -1.06 |
| Diluted EPS | -1.27 | -1.52 | -2.67 | -2.62 | -1.82 | -1.54 | -0.79 | -1.06 |
| Weighted Average OS | 82.89M | 69.37M | 49.64M | 48.86M | 46.04M | 43.06M | 42.99M | 14.79M |
| EBITDA | -$102.91M | -$103.37M | -$127.96M | -$124.28M | -$80.25M | -$58.83M | -$31.7M | -$15.12M |
| EBITDA Margin | -286.3% | -290.5% | -616.5% | -399.7% | -175.3% | -177.2% | -148.3% | -78.1% |
Balance Sheet
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 |
|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Assets | ||||||||
| Current Assets | ||||||||
| Cash and Cash Equivalents | $74.6M | $55.5M | $126.59M | $29.75M | $76.12M | $181.73M | $90.55M | $36.31M |
| Short-Term Investments | $173.93M | $189.41M | $127.09M | $246.4M | $233.16M | $189.96M | $0 | $0 |
| Cash and Short-Term Investments | $248.54M | $244.9M | $253.68M | $276.15M | $309.28M | $371.69M | $90.55M | $36.31M |
| Accounts Receivable | $2.4M | $3.1M | $11.8M | $1.47M | $5.72M | $4.48M | $4.62M | $86.44M |
| Inventory | $0 | $0 | $0 | -$60.96M | $0 | $0 | $0 | $0 |
| Other Current Assets | $7.17M | $9.76M | $5.71M | $70.89M | $0 | $0 | $0 | $0 |
| Total Current Assets | $258.11M | $257.77M | $271.19M | $287.56M | $325.69M | $381.01M | $96.77M | $123.53M |
| Long-Term Assets | ||||||||
| Property, Plant & Equipment Net | $45.28M | $63.38M | $71.09M | $77.52M | $35.05M | $16.55M | $18.92M | $20.38M |
| Goodwill | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Intangible Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Long-Term Investments | $48.56M | $22.36M | $28.01M | $60.96M | $142.2M | $0 | $0 | $2.58M |
| Deferred Tax Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Long-Term Assets | $7.13M | $6.1M | $6.17M | $4.8M | $3.82M | $2.58M | $2.58M | $0 |
| Total Long-Term Assets | $100.97M | $91.83M | $105.26M | $143.28M | $181.08M | $19.13M | $21.49M | $22.96M |
| Other Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Assets | $359.07M | $349.6M | $376.45M | $430.84M | $506.76M | $400.14M | $118.26M | $146.49M |
| Liabilities | ||||||||
| Current Liabilities | ||||||||
| Accounts Payable | $858K | $1.33M | $1.45M | $1.17M | $4.51M | $5.68M | $5.38M | $1.15M |
| Short-Term Debt | $0 | $0 | $0 | $2.29M | $0 | $0 | $0 | $0 |
| Current Income Tax Payable | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Current Unearned Revenue | $12.49M | $18.71M | $15.47M | $16.62M | $31.8M | $27.6M | $20.7M | $19.11M |
| Other Current Liabilities | $10.05M | $9.3M | $9.39M | $3.11M | $5.5M | $4.19M | $3.33M | $1.26M |
| Total Current Liabilities | $33.03M | $45.18M | $42.77M | $44.55M | $51.25M | $43.85M | $33.64M | $23.95M |
| Long-Term Liabilities | ||||||||
| Long-Term Debt | $0 | $0 | $0 | $9.2M | $10.77M | $10.05M | $0 | $0 |
| Long-Term Unearned Revenue | $15.84M | $28.46M | $21.81M | $16.89M | $24.37M | $53.62M | $72.72M | $77.55M |
| Long-Term Deferred Tax Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | -$13.75M |
| Other Long-Term Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $111M | $111M |
| Total Long-Term Liabilities | $69.46M | $88.44M | $87.57M | $97.06M | $65.91M | $75.5M | $196.58M | $202.29M |
| Other Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities | $102.49M | $133.62M | $130.34M | $141.61M | $117.16M | $119.35M | $230.22M | $226.24M |
| Stockholders' Equity | ||||||||
| Preferred Stock | $0 | $0 | $0 | $0 | $0 | $0 | $111M | $111M |
| Common Stock | $9K | $7K | $6K | $5K | $5K | $4K | $0 | $1K |
| Retained Earnings | -$738.69M | -$633.7M | -$528.38M | -$395.89M | -$267.71M | -$183.82M | -$117.49M | -$83.39M |
| Comprehensive Income & Other | $50K | $53K | -$127K | -$4.14M | -$775K | $13K | $0 | -$2.5M |
| Other Stockholders' Equity | $995.27M | $849.68M | $774.49M | $685.12M | $657.32M | $464.61M | $5.53M | $3.64M |
| Total Equity | $256.59M | $215.99M | $246.11M | $289.23M | $389.61M | $280.79M | -$111.96M | -$79.75M |
| Minority Interest | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities and Equity | $359.07M | $349.6M | $376.45M | $430.84M | $506.76M | $400.14M | $118.26M | $146.49M |
| Supplementary Data | ||||||||
| Total Debt | $59.98M | $65.76M | $70.98M | $87.15M | $42.88M | $22.92M | $13.75M | $14.48M |
| Net Debt | -$14.62M | $10.26M | -$55.61M | $57.4M | -$33.24M | -$158.81M | -$76.8M | -$21.83M |
Cash Flow Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 |
|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Operating Activities | ||||||||
| Net Income | -$104.99M | -$105.32M | -$132.49M | -$128.18M | -$83.89M | -$66.33M | -$34.1M | -$15.71M |
| Depreciation & Amortization | $1.96M | $1.82M | $1.88M | $1.68M | $1.49M | $1.62M | $1.59M | $1.27M |
| Deferred Income Tax | $0 | $0 | $0 | $0 | $1.88M | $5.58M | $350K | $66K |
| Stock-Based Compensation | $19.1M | $29.66M | $27.23M | $30.02M | $21.51M | $3.43M | $1.64M | $582K |
| Changes in Working Capital: | ||||||||
| Accounts Receivable | $701K | $8.7M | -$10.33M | $4.24M | -$1.23M | $139K | $81.81M | -$84.94M |
| Inventory | $0 | $0 | $0 | $0 | -$2.63M | -$1.58M | $2.17M | -$2.22M |
| Accounts Payable | -$468K | -$119K | $273K | -$3.33M | -$1.18M | $467K | $4.23M | $578K |
| Other Working Capital | -$29.52M | -$930K | $3.12M | -$17.69M | -$25.05M | -$12.2M | -$3.23M | $81.03M |
| Total Working Capital Change | -$29.28M | $7.65M | -$6.94M | -$16.78M | -$30.09M | -$13.18M | $84.98M | -$5.56M |
| Other Non-Cash Items | $14.52M | $1.03M | $3.48M | $7.32M | $2.13M | $1.63M | $1.14M | $2.37M |
| Net Cash from Operating | -$98.69M | -$65.16M | -$106.84M | -$105.94M | -$86.97M | -$67.25M | $55.61M | -$16.98M |
| Investing Activities | ||||||||
| Capital Expenditures | -$607K | -$180K | -$1.71M | -$5.5M | -$1.28M | -$650K | -$1.35M | -$2.69M |
| Acquisitions | $0 | $0 | $0 | -$63.92M | $188.06M | $189.85M | $63K | $0 |
| Purchases of Investments | -$227.07M | -$284.32M | -$129.9M | -$219.53M | -$537.74M | -$293.86M | -$79M | -$4.99M |
| Sales of Investments | $219.08M | $233.23M | $289.95M | $283.44M | $349.68M | $104M | $78.67M | $44.6M |
| Other Investing Activities | $0 | $0 | $0 | $63.92M | -$188.06M | -$189.85M | $0 | $39.61M |
| Net Cash from Investing | -$8.6M | -$51.27M | $158.35M | $58.42M | -$189.34M | -$190.5M | -$1.62M | $36.92M |
| Financing Activities | ||||||||
| Debt Repaid | - | - | $12.5M | - | - | -$11.97M | - | - |
| Common Stock Issuance | $126.32M | $44.37M | $57.67M | $777K | $169.47M | $340.6M | $0 | $47K |
| Common Stock Repurchases | -$193K | -$194K | -$110K | $0 | $0 | -$194K | -$30K | -$63K |
| Dividends Paid | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Financing Activities | $274K | $1.16M | $426K | $370K | $1.94M | -$3.45M | $274K | -$63K |
| Net Cash from Financing | $126.4M | $45.34M | $45.49M | $1.15M | $171.4M | $348.93M | $244K | $1.96M |
| Forex Effect | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | $19.1M | -$71.09M | $97M | -$46.37M | -$104.9M | $91.18M | $54.24M | $21.9M |
| Supplementary Data | ||||||||
| Operating Cash Flow | -$98.69M | -$65.16M | -$106.84M | -$105.94M | -$86.97M | -$67.25M | $55.61M | -$16.98M |
| Capital Expenditure | -$607K | -$180K | -$1.71M | -$5.5M | -$1.28M | -$650K | -$1.35M | -$2.69M |
| Free Cash Flow | -$99.3M | -$65.34M | -$108.55M | -$111.44M | -$88.24M | -$67.9M | $54.27M | -$19.67M |
| Cash at Beginning | $58.94M | $130.03M | $33.03M | $79.4M | $184.3M | $93.13M | $38.89M | $16.99M |
| Cash at End | $78.05M | $58.94M | $130.03M | $33.03M | $79.4M | $184.3M | $93.13M | $38.89M |