Climb Bio, Inc. (CLYM)
Climb Bio, Inc. is a biopharmaceutical firm dedicated to crafting therapeutic solutions for inflammatory diseases driven by autoimmune responses. Its primary investigational asset is budoprutug, an anti-CD19 monoclonal antibody. This treatment is being advanced for a range of autoimmune conditions, including systemic lupus erythematosus, lupus nephritis, immune thrombocytopenia, and membranous nephropathy. The entity, established in 2018, officially rebranded as Climb Bio, Inc. in October 2024, having previously operated under the name Eliem Therapeutics, Inc. Its corporate headquarters are situated in Wilmington, Delaware.
Sector: Pharmaceutical Preparations
Industry: Biotechnology
Climb Bio, Inc.
- CLYM116/MIL116READOUTCash runway at this date: 2yr
- CLYM116READOUTCash runway at this date: 2yr
- budoprutugREADOUTCash runway at this date: 23mo
Trials need funding. See this company's dilution risk and cash position.
- Phase 2Completed
Efficacy and Safety of ETX-018810 for the Treatment of Diabetic Peripheral Neuropathic Pain
ETX-018810, Placebo
Diabetic Peripheral Neuropathic Pain, Diabetic Peripheral Neuropathy
NCT04688671Enrollment167StartNov 2020Primary CompletionFeb 2022CompletionFeb 2022 - Phase 2Completed
Efficacy and Safety of ETX-018810 in Subjects With Lumbosacral Radicular Pain
ETX-018810, Placebo
Lumbosacral Radiculopathy
NCT04778592Enrollment149StartJan 2021Primary CompletionMay 2022CompletionMay 2022 - Phase 2Recruiting
A Phase 2 Study of Budoprutug in Subjects With Primary Membranous Nephropathy
budoprutug
Primary Membranous Nephropathy
NCT07096843Enrollment45StartAug 2025Primary CompletionOct 2027est.CompletionOct 2027est. - Phase 1/2Recruiting
A Phase 1b/2a Study of Budoprutug in Subjects With Immune Thrombocytopenia (ITP)
Budoprutug
Immune Thrombocytopenia (ITP), ITP +3
NCT07043946Enrollment24StartJun 2025Primary CompletionAug 2027est.CompletionAug 2028est. - Phase 1/2Recruiting
A Phase 1b/2a Study of Budoprutug in Systemic Lupus Erythematosus (SLE)
Budoprutug
Systemic Lupus Erthematosus
NCT07564596Enrollment30StartJun 2026Primary CompletionSep 2027est.CompletionSep 2027est. - Phase 1Recruiting
A Phase 1b Study of Budoprutug in Systemic Lupus Erythematosus (SLE)
Budoprutug
Systemic Lupus Erythematosus
NCT07011043Enrollment30StartJul 2025Primary CompletionApr 2027est.CompletionApr 2027est. - Phase 1Recruiting
A Phase 1 Study of CLYM116 in Normal Healthy Volunteers
CLYM116, Placebo
Healthy Volunteers
NCT07248865Enrollment48StartDec 2025Primary CompletionJul 2026est.CompletionSep 2026est. - Early Phase 1Completed
A Phase 1 Study of Budoprutug (TNT119) Subcutaneous and Intravenous Injections in Normal Healthy Volunteers
Budoprutug, Placebo
Healthy Volunteers
NCT07090655Enrollment30StartAug 2025Primary CompletionApr 2026CompletionApr 2026
| Drug / Therapy | Link | ||
|---|---|---|---|
| Phase 2 | Completed | ETX-018810, Placebo | NCT04688671 |
| Phase 2 | Completed | ETX-018810, Placebo | NCT04778592 |
| Phase 2 | Recruiting | budoprutug | NCT07096843 |
| Phase 1/2 | Recruiting | Budoprutug | NCT07043946 |
| Phase 1/2 | Recruiting | Budoprutug | NCT07564596 |
| Phase 1 | Recruiting | Budoprutug | NCT07011043 |
| Phase 1 | Recruiting | CLYM116, Placebo | NCT07248865 |
| Early Phase 1 | Completed | Budoprutug, Placebo | NCT07090655 |