Caribou Biosciences, Inc. (CRBU)
Caribou Biosciences, Inc. operates as a clinical-stage biopharmaceutical firm dedicated to pioneering genome-edited allogeneic cell therapies. These cutting-edge treatments are engineered to address both hematologic malignancies (blood cancers) and solid tumors, serving patients across the United States and internationally. Among its primary therapeutic candidates are CB-010, an allogeneic anti-CD19 CAR-T cell therapy currently undergoing Phase 1 clinical trials for relapsed or refractory B cell non-Hodgkin lymphoma, and CB-011, an allogeneic anti-BCMA CAR-T cell therapy targeting relapsed or refractory multiple myeloma. Caribou Biosciences is additionally developing CB-012, an allogeneic anti-CD371 CAR-T cell therapy for relapsed or refractory acute myeloid leukemia, along with CB-020, an allogeneic CAR-NK cell therapy aimed at solid tumors. The company also maintains a collaborative agreement with AbbVie Manufacturing Management Unlimited Company for the joint advancement of CAR-T cell therapies. Founded in 2011, Caribou Biosciences' headquarters are located in Berkeley, California.
Sector: Biological Products, (No Diagnostic Substances)
Industry: Biotechnology
Caribou Biosciences, Inc.
NASDAQ:CRBUHealthcare · Biotechnology
-4.86%$0.5328
AH Close$0.5306-0.41%vs close
AH Close$0.5306-0.41%vs close
Mkt Cap$57.12M
Float93.21M
O/S107.21M
Inst Own45.4%
SI13.9%
Dilution
Delisting Issues Timeline
Financials Summary
Revenue$11.16M
Net Income-$148.13M
Total Assets$175.37M
Free Cash Flow-$112.35M
Debt & Equity
Debt 18%
Equity 82%
Total Debt$27.23M
Total Equity$122.17M
Shares Outstanding
Short Interest
Split History
No splits on record
Nothing in CRBU's public trading history: no forward or reverse split has affected the share count.
Balance Sheet Details
Assets$175.37M
Liabilities$53.19M
Accounts Receivable$2.98M
Accounts Payable$5.78M
Inventory$0
PP&E (Net)$24.43M
Goodwill$0
Intangible Assets$0
Income Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Revenue | $11.16M | $9.99M | $34.48M | $13.85M | $9.6M | $12.36M | $5.79M |
| YoY Growth | 11.7% | -71.0% | 148.9% | 44.3% | -22.4% | 113.6% | - |
| Cost of Revenue | $3.65M | $3.93M | $3.52M | $3.64M | $984K | $34.42M | $0 |
| Gross Profit | $7.51M | $6.07M | $30.95M | $10.21M | $8.61M | -$22.06M | $5.79M |
| Gross Margin | 67.3% | 60.7% | 89.8% | 73.7% | 89.7% | -178.5% | 100.0% |
| Research and Development | $109.44M | $130.15M | $112.08M | $82.23M | $52.26M | $34.42M | $23.64M |
| Selling, General, and Administrative | $37.91M | $46.46M | $38.46M | $38.02M | $23.34M | $14.06M | $16.46M |
| Other | -$3.65M | -$3.93M | -$3.52M | -$3.64M | $0 | -$34.42M | $0 |
| Total Operating Expenses | $143.71M | $172.68M | $147.01M | $116.61M | $75.59M | $14.06M | $40.09M |
| Operating Income (EBIT) | -$136.19M | -$166.62M | -$116.06M | -$106.4M | -$66.98M | -$36.12M | -$34.3M |
| Operating Margin | -1220.5% | -1667.2% | -336.6% | -768.2% | -697.8% | -292.2% | -592.7% |
| Interest Expense | $0 | $0 | $0 | $0 | $8K | $20K | $4K |
| Interest Income | $8M | $0 | $10.7M | $4.6M | $148K | $236K | $1.05M |
| Other Income (Expense) | -$12.48M | $17.5M | $14.18M | $7.05M | $377K | -$3K | $3.34M |
| Income Before Tax (EBT) | -$148.68M | -$149.11M | -$101.88M | -$99.35M | -$66.6M | -$36.13M | -$30.97M |
| Income Tax Expense | -$550K | -$9K | $193K | $70K | $321K | -$1.82M | -$7.54M |
| Net Income | -$148.13M | -$149.1M | -$102.07M | -$99.42M | -$66.92M | -$34.31M | -$23.43M |
| Net Income Margin | -1327.4% | -1491.9% | -296.1% | -717.8% | -697.3% | -277.6% | -404.8% |
| Supplementary Data | |||||||
| EPS | -1.59 | -1.65 | -1.38 | -1.64 | -1.11 | -1.24 | -0.85 |
| Diluted EPS | -1.59 | -1.65 | -1.38 | -1.64 | -1.11 | -1.24 | -0.85 |
| Weighted Average OS | 93.39M | 90.32M | 73.81M | 60.80M | 60.26M | 27.66M | 27.66M |
| EBITDA | -$145.03M | -$145.19M | -$98.35M | -$97.73M | -$65.61M | -$35.21M | -$30.21M |
| EBITDA Margin | -1299.7% | -1452.7% | -285.3% | -705.6% | -683.6% | -284.8% | -522.0% |
Balance Sheet
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Assets | |||||||
| Current Assets | |||||||
| Cash and Cash Equivalents | $12.36M | $16.29M | $51.16M | $58.34M | $240.42M | $15.95M | $41.07M |
| Short-Term Investments | $126.98M | $193.24M | $277.67M | $189.32M | $135.41M | $0 | $8.4M |
| Cash and Short-Term Investments | $139.34M | $209.54M | $328.83M | $247.66M | $375.83M | $15.95M | $49.47M |
| Accounts Receivable | $2.98M | $3.25M | $3.86M | $4.66M | $8.12M | $5.16M | $3.98M |
| Inventory | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Current Assets | $2.91M | $1.78M | $1.22M | $1.12M | $671K | $423K | $373K |
| Total Current Assets | $145.23M | $219.38M | $338.84M | $260.25M | $391.19M | $24.31M | $57.01M |
| Long-Term Assets | |||||||
| Property, Plant & Equipment Net | $24.43M | $39.29M | $40.45M | $34.91M | $4.89M | $3.5M | $4.33M |
| Goodwill | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Intangible Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Long-Term Investments | $3.55M | $49.13M | $51.33M | $77.07M | $45.3M | $7.63M | $0 |
| Deferred Tax Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Long-Term Assets | $2.15M | $5.52M | $1.59M | $1.54M | $975K | $612K | $593K |
| Total Long-Term Assets | $30.14M | $93.94M | $93.37M | $113.52M | $51.16M | $11.74M | $4.92M |
| Other Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Assets | $175.37M | $313.31M | $432.21M | $373.76M | $442.36M | $36.05M | $61.93M |
| Liabilities | |||||||
| Current Liabilities | |||||||
| Accounts Payable | $5.78M | $2.48M | $3.12M | $1.15M | $3.99M | $2.6M | $2.54M |
| Short-Term Debt | $0 | $0 | $0 | $0 | $259K | $654K | $532K |
| Current Income Tax Payable | $0 | $0 | $0 | $0 | $0 | $5K | $11K |
| Current Unearned Revenue | $1.9M | $3.13M | $2.85M | $9.94M | $8.7M | $161K | $717K |
| Other Current Liabilities | $8.56M | $10.22M | $10.62M | $7.12M | $4.75M | $629K | $496K |
| Total Current Liabilities | $25.41M | $30.65M | $28.3M | $28.13M | $25.83M | $12.39M | $10.08M |
| Long-Term Liabilities | |||||||
| Long-Term Debt | $0 | $0 | $0 | $0 | $0 | $924K | $0 |
| Long-Term Unearned Revenue | $1.75M | $3.32M | $6.1M | $15.95M | $22.03M | $937K | $986K |
| Long-Term Deferred Tax Liabilities | $4.26M | $548K | $557K | $381K | $476K | $155K | $650K |
| Other Long-Term Liabilities | -$4.26M | $785K | $2.94M | $1.65M | $6.19M | $45.08M | $42.76M |
| Total Long-Term Liabilities | $27.78M | $29.71M | $35.51M | $44.77M | $28.7M | $47.09M | $44.39M |
| Other Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities | $53.19M | $60.36M | $63.81M | $72.89M | $54.53M | $59.48M | $54.47M |
| Stockholders' Equity | |||||||
| Preferred Stock | $0 | $0 | $0 | $0 | $0 | $41.32M | $41.32M |
| Common Stock | $9K | $9K | $8K | $6K | $6K | $1K | $1K |
| Retained Earnings | -$596.51M | -$448.39M | -$299.29M | -$197.22M | -$97.79M | -$30.87M | $3.44M |
| Comprehensive Income & Other | $103K | $255K | $30K | -$1.52M | -$135K | $0 | $0 |
| Other Stockholders' Equity | $718.68M | $701.33M | $667.68M | $498.08M | $485.61M | $7.43M | $4.03M |
| Total Equity | $122.17M | $252.95M | $368.4M | $300.87M | $387.82M | -$23.44M | $7.46M |
| Minority Interest | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities and Equity | $175.37M | $313.31M | $432.21M | $373.76M | $442.36M | $36.05M | $61.93M |
| Supplementary Data | |||||||
| Total Debt | $27.23M | $26.49M | $27.11M | $27.75M | $259K | $1.58M | $532K |
| Net Debt | $14.87M | $10.19M | -$24.05M | -$30.59M | -$240.42M | -$14.38M | -$40.54M |
Cash Flow Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Operating Activities | |||||||
| Net Income | -$148.13M | -$149.1M | -$102.07M | -$99.42M | -$66.92M | -$34.31M | -$23.43M |
| Depreciation & Amortization | $3.65M | $3.93M | $3.52M | $1.62M | $984K | $900K | $751K |
| Deferred Income Tax | -$548K | $0 | $0 | $0 | $0 | $0 | $0 |
| Stock-Based Compensation | $12.68M | $16.71M | $13.75M | $11.72M | $3.45M | $1M | $1.23M |
| Changes in Working Capital: | |||||||
| Accounts Receivable | $272K | $608K | $805K | $3.46M | -$2.96M | -$1.18M | -$1.09M |
| Inventory | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Accounts Payable | $3.25M | -$354K | $1.82M | -$2.72M | $1.14M | $43K | $1.18M |
| Other Working Capital | -$4.01M | -$5.37M | -$9.94M | -$4.94M | $30.89M | $1.31M | -$8.35M |
| Total Working Capital Change | -$484K | -$5.11M | -$7.32M | -$4.2M | $29.07M | $177K | -$8.27M |
| Other Non-Cash Items | $21.84M | -$4.61M | -$1.18M | -$679K | $904K | -$986K | -$2.29M |
| Net Cash from Operating | -$110.99M | -$138.2M | -$93.29M | -$90.97M | -$32.52M | -$33.22M | -$32.01M |
| Investing Activities | |||||||
| Capital Expenditures | -$1.36M | -$4.88M | -$11.61M | -$6.45M | -$2.12M | -$317K | -$884K |
| Acquisitions | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Purchases of Investments | -$150.37M | -$304.39M | -$394.76M | -$339.06M | -$173.28M | $0 | $0 |
| Sales of Investments | $252.83M | $397.49M | $338.19M | $252.87M | $0 | $7.67M | $28.12M |
| Other Investing Activities | $1.14M | -$1.61M | $0 | -$600K | -$1M | -$988K | $0 |
| Net Cash from Investing | $102.24M | $86.61M | -$68.18M | -$93.25M | -$176.4M | $6.36M | $27.23M |
| Financing Activities | |||||||
| Debt Repaid | - | - | - | - | -$1.03M | -$1.47M | $45K |
| Common Stock Issuance | $4.82M | $15.19M | $152.72M | $2.13M | $321.02M | $270K | $217K |
| Common Stock Repurchases | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Dividends Paid | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Financing Activities | $0 | $1.53M | $1.58M | $0 | $2.55M | $0 | $0 |
| Net Cash from Financing | $4.82M | $16.72M | $154.3M | $2.13M | $433.43M | $1.74M | $172K |
| Forex Effect | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | -$3.93M | -$34.87M | -$7.18M | -$182.08M | $224.51M | -$25.12M | -$4.6M |
| Supplementary Data | |||||||
| Operating Cash Flow | -$110.99M | -$138.2M | -$93.29M | -$90.97M | -$32.52M | -$33.22M | -$32.01M |
| Capital Expenditure | -$1.36M | -$6.5M | -$11.61M | -$7.05M | -$3.12M | -$1.31M | -$884K |
| Free Cash Flow | -$112.35M | -$144.71M | -$104.9M | -$98.02M | -$35.64M | -$34.53M | -$32.89M |
| Cash at Beginning | $16.34M | $51.21M | $58.38M | $240.47M | $15.95M | $41.07M | $45.67M |
| Cash at End | $12.41M | $16.34M | $51.21M | $58.38M | $240.47M | $15.95M | $41.07M |