CASTLE BIOSCIENCES INC (CSTL)
Castle Biosciences, Inc. functions as a commercial-stage diagnostics firm, with its primary objective being the provision of both diagnostic and prognostic testing services, specifically targeting various dermatological cancers. Their flagship product, DecisionDx-Melanoma, represents an advanced multi-gene expression profile (GEP) assay engineered to assess the probability of metastasis in patients afflicted with invasive cutaneous melanoma. In addition to their leading solution, the company has created several other specialized, proprietary tests. Among these is DecisionDx-UM, a GEP test tailored to forecast the risk of metastasis for individuals with uveal melanoma, a less common malignancy of the eye. Another key offering is DecisionDx-SCC, a distinctive 40-gene expression profile test that utilizes a patient's unique tumor biology to predict their specific risk of squamous cell carcinoma metastasis, particularly for those presenting with recognized risk factors. Moreover, they offer DecisionDx DiffDx-Melanoma and myPath Melanoma, both proprietary GEP tests employed to assist in the accurate diagnosis of ambiguous pigmented lesions. These specialized testing services are provided by Castle Biosciences to patients predominantly through their healthcare providers. The organization commenced operations in 2007 and maintains its corporate headquarters in Friendswood, Texas.
Sector: Services-Medical Laboratories
Industry: Medical - Diagnostics & Research
Castle Biosciences, Inc.
Trials need funding. See this company's dilution risk and cash position.
- ObservationalTerminated
5-year Study to Track Clinical Application of DecisionDx-Melanoma Gene Expression Profile Assay Results
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Cutaneous Melanoma
NCT02355574Enrollment301StartJun 2014Primary CompletionFeb 2021CompletionJul 2021 - ObservationalTerminated
Five Year Study to Track Use of DecisionDX-Melanoma Test in Patients With Cutaneous Melanoma and Associated Patient Outcomes
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Cutaneous Melanoma
NCT02355587Enrollment72StartMar 2014Primary CompletionJul 2021CompletionJul 2021 - ObservationalCompleted
5 Year Registry Study to Track Clinical Application of DecisionDx-UM Assay Results and Associated Patient Outcomes
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Uveal Melanoma
NCT02376920Enrollment93StartMar 2010Primary CompletionApr 2022CompletionApr 2022 - ObservationalTerminated
Prospective Validation Study for the Proprietary Rectal and Anal Cancer Protein Expression Assays
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Rectal Adenocarcinoma, Anal Adenocarcinoma +1
NCT02407561Enrollment3StartFeb 2015Primary CompletionJul 2016CompletionJul 2016 - ObservationalRecruiting
Evaluation of a Non-Invasive Device for Early Detection of Atopic Dermatitis Flares
Nevisense electrical impedance spectroscopy
Atopic Dermatitis
NCT07645820Enrollment450StartJun 2026Primary CompletionApr 2027est.CompletionDec 2027est.
| Drug / Therapy | Link | ||
|---|---|---|---|
| Observational | Terminated | - | NCT02355574 |
| Observational | Terminated | - | NCT02355587 |
| Observational | Completed | - | NCT02376920 |
| Observational | Terminated | - | NCT02407561 |
| Observational | Recruiting | Nevisense electrical impedance spectroscopy | NCT07645820 |