CytomX Therapeutics, Inc. (CTMX)
CytomX Therapeutics, Inc. is a United States-based biopharmaceutical company primarily focused on creating treatments for cancer. The company utilizes its proprietary Probody technology platform to engineer targeted antibody therapeutics for oncological applications. Its robust clinical pipeline includes several notable drug candidates. CX-2009, an antibody-drug conjugate (ADC) designed to target CD166, is currently in Phase II clinical trials for treating breast cancer. Another investigational therapy, CX-2029, has also reached Phase II trials, where it is being evaluated for various cancers such as squamous non-small cell lung cancer, head and neck squamous cell carcinoma, esophageal and gastro-esophageal junction cancers, and diffuse large B-cell lymphoma. Additionally, CytomX is progressing two CTLA-4 Probody therapeutics: BMS-986249, which is undergoing Phase I/II clinical trials for metastatic melanoma, and BMS-986288, in Phase I trials for solid tumors. Beyond these, the company is developing CX-2043, a conditionally activated ADC targeting the epithelial cell adhesion molecule, and CX-904, a conditionally activated epidermal growth factor receptor, both aimed at addressing solid tumor conditions. CytomX has forged strategic partnerships with leading pharmaceutical firms, including AbbVie Ireland Unlimited Company, Amgen, Inc., Bristol-Myers Squibb Company, ImmunoGen, Inc., Pfizer Inc., and Astellas Pharma Inc., to collaboratively advance its Probody therapeutics. The company was founded in 2008 and its main office is located in South San Francisco, California.
Sector: Pharmaceutical Preparations
Industry: Biotechnology
CytomX Therapeutics, Inc.
NASDAQ:CTMXHealthcare · Biotechnology
+2.18%$2.34
AH$2.38+1.71%vs close
Mkt Cap$509.88M
Float200.29M
O/S217.9M
Vol
$ Vol
RVOL
Inst Own98.4%
SI21.4%
Earnings
Dilution
Financials Summary
Revenue$76.2M
Net Income-$17.37M
Total Assets$151.57M
Free Cash Flow-$75.81M
Debt & Equity
Debt 4%
Equity 96%
Total Debt$4.24M
Total Equity$99.01M
Shares Outstanding
Short Interest
Split History
No splits on record
Nothing in CTMX's public trading history: no forward or reverse split has affected the share count.
Balance Sheet Details
Assets$151.57M
Liabilities$52.56M
Accounts Receivable$2.01M
Accounts Payable$1.3M
Inventory$0
PP&E (Net)$4.7M
Goodwill$949K
Intangible Assets$438K
Income Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 | FY 2014 | FY 2013 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 | 2014-12-31 | 2013-12-31 |
| Revenue | $76.2M | $138.1M | $101.21M | $53.16M | $37.31M | $68.43M | $57.49M | $59.5M | $71.62M | $15.04M | $7.71M | $5.08M | $888K |
| YoY Growth | -44.8% | 36.4% | 90.4% | 42.5% | -45.5% | 19.0% | -3.4% | -16.9% | 376.1% | 95.1% | 51.9% | 471.7% | - |
| Cost of Revenue | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Gross Profit | $76.2M | $138.1M | $101.21M | $53.16M | $37.31M | $68.43M | $57.49M | $59.5M | $71.62M | $15.04M | $7.71M | $5.08M | $888K |
| Gross Margin | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% |
| Research and Development | $68.73M | $83.38M | $77.68M | $111.65M | $114.19M | $112.94M | $131.62M | $103.87M | $92.28M | $54.76M | $28.36M | $28.3M | $10.89M |
| Selling, General, and Administrative | $29.84M | $29.73M | $30.02M | $42.85M | $39.16M | $36.03M | $36.77M | $33.51M | $25.61M | $19.87M | $12.56M | $6.54M | $4.95M |
| Other | $0 | $0 | $0 | $0 | $0 | $0 | -$135K | -$68K | -$27K | -$69K | $0 | -$55K | $71K |
| Total Operating Expenses | $98.56M | $113.11M | $107.7M | $154.5M | $153.35M | $148.97M | $168.38M | $137.38M | $117.88M | $74.63M | $40.91M | $34.84M | $15.84M |
| Operating Income (EBIT) | -$22.36M | $25M | -$6.48M | -$101.33M | -$116.04M | -$80.54M | -$110.89M | -$77.87M | -$46.26M | -$59.59M | -$33.2M | -$29.77M | -$14.96M |
| Operating Margin | -29.3% | 18.1% | -6.4% | -190.6% | -311.0% | -117.7% | -192.9% | -130.9% | -64.6% | -396.1% | -430.5% | -586.3% | -1684.2% |
| Interest Expense | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $1.69M | $1.73M | $487K | $254K |
| Interest Income | $5.21M | $7.14M | $9.84M | $1.68M | $255K | $1.84M | $8.37M | $7.64M | $2.67M | $2.42M | $1.31M | $7K | $6K |
| Other Income (Expense) | $5.23M | $7.1M | $9.81M | $2.02M | $172K | $29.63M | $8.23M | $7.57M | $2.65M | $667K | -$2.16M | -$535K | -$177K |
| Income Before Tax (EBT) | -$17.13M | $32.09M | $3.32M | -$99.32M | -$115.87M | -$50.91M | -$102.67M | -$70.3M | -$43.61M | -$58.92M | -$35.36M | -$30.3M | -$15.13M |
| Income Tax Expense | $238K | $224K | $3.89M | $0 | $0 | $13.91M | -$427K | $14.3M | -$513K | -$19K | $10K | $10K | $10K |
| Net Income | -$17.37M | $31.87M | -$569K | -$99.32M | -$115.87M | -$64.82M | -$102.24M | -$84.6M | -$43.1M | -$58.9M | -$35.37M | -$30.31M | -$15.14M |
| Net Income Margin | -22.8% | 23.1% | -0.6% | -186.8% | -310.5% | -94.7% | -177.8% | -142.2% | -60.2% | -391.5% | -458.7% | -597.0% | -1705.3% |
| Supplementary Data | |||||||||||||
| EPS | -0.15 | 0.38 | -0.01 | -1.48 | -1.26 | -0.71 | -2.26 | -2.03 | -1.16 | -1.63 | -1.00 | -0.87 | -15.32 |
| Diluted EPS | -0.15 | 0.38 | -0.01 | -1.48 | -1.26 | -0.71 | -2.26 | -2.03 | -1.16 | -1.63 | -1.00 | -0.87 | -15.32 |
| Weighted Average OS | 137.94M | 84.44M | 73.81M | 65.74M | 64.15M | 46.15M | 45.34M | 41.66M | 37.17M | 36.23M | 35.48M | 34.92M | 988,511 |
| EBITDA | -$15.75M | $33.86M | $5.5M | -$96.87M | -$113.16M | -$77.97M | -$100.06M | -$75.99M | -$41.97M | -$57.85M | -$32.43M | -$29.03M | -$14.22M |
| EBITDA Margin | -20.7% | 24.5% | 5.4% | -182.2% | -303.3% | -113.9% | -174.1% | -127.7% | -58.6% | -384.6% | -420.5% | -571.8% | -1601.8% |
Balance Sheet
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 | FY 2014 | FY 2013 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 | 2014-12-31 | 2013-12-31 |
| Assets | |||||||||||||
| Current Assets | |||||||||||||
| Cash and Cash Equivalents | $12.67M | $38.05M | $17.17M | $193.65M | $205.53M | $191.86M | $188.43M | $247.58M | $177.55M | $104.64M | $59.82M | $64.4M | $8.7M |
| Short-Term Investments | $124.39M | $62.57M | $157.34M | $0 | $99.7M | $124.26M | $107.72M | $188.55M | $196.56M | $77.29M | $126.89M | $0 | $0 |
| Cash and Short-Term Investments | $137.05M | $100.62M | $174.51M | $193.65M | $305.23M | $316.12M | $296.14M | $436.13M | $374.11M | $181.94M | $186.71M | $64.4M | $8.7M |
| Accounts Receivable | $2.01M | $3.1M | $3.43M | $35.99M | $790K | $798K | $13K | $97K | $10.14M | $2.31M | $744K | $1.88M | $237K |
| Inventory | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $100K | $100K |
| Other Current Assets | $4.86M | $3.58M | $5M | $7.47M | $0 | $0 | $0 | $9.25M | $4.35M | $0 | $2.3M | $100K | $100K |
| Total Current Assets | $143.92M | $107.31M | $182.94M | $237.1M | $310.3M | $324.01M | $303.33M | $445.48M | $388.6M | $188.15M | $189.75M | $66.85M | $9.27M |
| Long-Term Assets | |||||||||||||
| Property, Plant & Equipment Net | $4.7M | $10.6M | $16.18M | $21.02M | $25.32M | $29.45M | $32.75M | $6.93M | $4.22M | $4.39M | $3.48M | $3.02M | $2.07M |
| Goodwill | $949K | $949K | $949K | $949K | $949K | $949K | $949K | $949K | $949K | $949K | $949K | $949K | $949K |
| Intangible Assets | $438K | $583K | $729K | $875K | $1.02M | $1.17M | $1.31M | $1.46M | $1.6M | $1.75M | $1.75M | $1.75M | $1.75M |
| Long-Term Investments | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $917K | $917K | $0 | $995K | $0 | $0 |
| Deferred Tax Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $1.14M | $398K | $0 | $401K | $0 | $0 |
| Other Long-Term Assets | $1.56M | $1.09M | $1M | $944K | $1.82M | $3.09M | $2.93M | $238K | $957K | $3.89M | -$115K | $492K | $148K |
| Total Long-Term Assets | $7.64M | $13.23M | $18.86M | $23.79M | $29.11M | $34.65M | $37.95M | $11.63M | $9.04M | $10.98M | $7.46M | $6.21M | $4.92M |
| Other Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Assets | $151.57M | $120.53M | $201.79M | $260.89M | $339.41M | $358.66M | $341.28M | $457.11M | $397.64M | $199.13M | $197.22M | $73.06M | $14.18M |
| Liabilities | |||||||||||||
| Current Liabilities | |||||||||||||
| Accounts Payable | $1.3M | $1.09M | $1.46M | $2.81M | $2.82M | $3M | $4.16M | $5.13M | $4.21M | $6.6M | $4.7M | $1.92M | $930K |
| Short-Term Debt | $4.24M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $1.42M | $1.26M |
| Current Income Tax Payable | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $13.34M | $0 | $0 | $0 | $0 | $0 |
| Current Unearned Revenue | $26.88M | $67.2M | $132.27M | $121.27M | $40.82M | $42.06M | $51.38M | $52.71M | $40.56M | $20.35M | $6.13M | $6.13M | $857K |
| Other Current Liabilities | $5.99M | $0 | $9.44M | $0 | $0 | $0 | $0 | $20.14M | $11.86M | $4.85M | $2.07M | $836K | $405K |
| Total Current Liabilities | $46.62M | $85.77M | $155.91M | $152.61M | $77.87M | $68.11M | $85.59M | $97.91M | $61.15M | $35.77M | $15.74M | $11.16M | $4.17M |
| Long-Term Liabilities | |||||||||||||
| Long-Term Debt | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $1.57M | $2.94M |
| Long-Term Unearned Revenue | $1.59M | $26.86M | $80.05M | $180.06M | $243.94M | $276.65M | $178.86M | $225.27M | $264.7M | $83.8M | $54.7M | $60.83M | $4.64M |
| Long-Term Deferred Tax Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $1.14M | $398K | $513K | $507K | $499K | $491K |
| Other Long-Term Liabilities | $4.35M | $4.12M | $3.89M | $0 | $0 | $0 | $850K | $3.05M | $1.9M | $566K | $198K | $77.54M | $46.21M |
| Total Long-Term Liabilities | $5.94M | $35.22M | $93.33M | $194.03M | $262M | $298.33M | $204.58M | $228.32M | $266.6M | $84.88M | $55.41M | $140.44M | $54.29M |
| Other Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities | $52.56M | $120.99M | $249.24M | $346.64M | $339.87M | $366.44M | $290.17M | $326.23M | $327.75M | $120.65M | $71.15M | $151.6M | $58.46M |
| Stockholders' Equity | |||||||||||||
| Preferred Stock | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $76.9M | $44.86M |
| Common Stock | $2K | $1K | $1K | $1K | $1K | $1K | $1K | $1K | $1K | $1K | $1K | $1K | $1K |
| Retained Earnings | -$711.95M | -$691.58M | -$723.45M | -$722.88M | -$623.56M | -$507.69M | -$417.23M | -$314.98M | -$219.47M | -$176.37M | -$117.47M | -$78.14M | -$43.88M |
| Comprehensive Income & Other | $111K | $27K | $95K | $10K | -$242K | -$47K | $57K | -$93K | -$94K | -$27K | -$76K | -$404K | -$399K |
| Other Stockholders' Equity | $810.96M | $691.12M | $676M | $637.13M | $623.1M | $499.92M | $468.34M | $445.86M | $289.36M | $254.84M | $243.53M | -$404K | -$399K |
| Total Equity | $99.01M | -$456K | -$47.45M | -$85.75M | -$459K | -$7.77M | $51.11M | $130.88M | $69.9M | $78.48M | $126.07M | -$78.54M | -$44.28M |
| Minority Interest | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities and Equity | $151.57M | $120.53M | $201.79M | $260.89M | $339.41M | $358.66M | $341.28M | $457.11M | $397.64M | $199.13M | $197.22M | $73.06M | $14.18M |
| Supplementary Data | |||||||||||||
| Total Debt | $4.24M | $9.38M | $13.97M | $18.06M | $21.67M | $24.87M | $27.68M | $0 | $0 | $0 | $0 | $2.99M | $4.2M |
| Net Debt | -$8.43M | -$28.67M | -$3.2M | -$175.59M | -$183.86M | -$166.99M | -$160.74M | -$247.58M | -$177.55M | -$104.64M | -$59.82M | -$61.41M | -$4.5M |
Cash Flow Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 | FY 2014 | FY 2013 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 | 2014-12-31 | 2013-12-31 |
| Operating Activities | |||||||||||||
| Net Income | -$17.37M | $31.87M | -$569K | -$99.32M | -$83.61M | -$32.88M | -$132.82M | -$84.6M | -$43.1M | -$58.9M | -$35.37M | -$30.31M | -$15.14M |
| Depreciation & Amortization | $1.38M | $1.77M | $2.17M | $2.44M | $2.71M | $2.57M | $2.6M | $1.88M | $1.65M | $1.73M | $1.21M | $783K | $655K |
| Deferred Income Tax | $0 | $0 | $0 | $0 | $272K | -$236K | $0 | $0 | -$513K | $6K | $8K | $8K | $10K |
| Stock-Based Compensation | $6.3M | $7.67M | $8.56M | $13.13M | $13.17M | $14.79M | $19.1M | $16.88M | $11.29M | $10.1M | $3.99M | $553K | $343K |
| Changes in Working Capital: | |||||||||||||
| Accounts Receivable | $1.09M | $329K | $32.55M | -$35.2M | $8K | -$785K | $84K | $10.04M | -$7.83M | -$1.57M | $1.13M | -$1.64M | -$237K |
| Inventory | $0 | $0 | $0 | $0 | $11.64M | -$11.12M | $0 | $19.91M | $10.32M | -$253K | $1.81M | $188K | $329K |
| Accounts Payable | $221K | -$297K | -$1.43M | $68K | -$139K | -$857K | -$374K | $261K | -$2.44M | $1.76M | $2.94M | $660K | $366K |
| Other Working Capital | -$69.89M | -$126.45M | -$93.64M | $4.47M | -$66.21M | $30.89M | -$31.12M | -$38.2M | $189.91M | $43.32M | -$6.13M | $61.46M | $5.5M |
| Total Working Capital Change | -$68.58M | -$126.42M | -$62.51M | -$30.65M | -$54.7M | $18.13M | -$31.41M | -$7.98M | $189.97M | $43.26M | -$248K | $60.67M | $5.96M |
| Other Non-Cash Items | $2.68M | -$1.12M | -$3.69M | $3.62M | $3.13M | $2.89M | $2.05M | -$1.7M | $11.09M | $1.77M | $3.01M | $95K | $169K |
| Net Cash from Operating | -$75.59M | -$86.23M | -$56.03M | -$110.79M | -$119.03M | $5.26M | -$140.48M | -$75.52M | $170.37M | -$2.03M | -$27.41M | $31.8M | -$8.01M |
| Investing Activities | |||||||||||||
| Capital Expenditures | -$220K | -$310K | -$840K | -$1.74M | -$1.61M | -$2.31M | -$3.5M | -$3.79M | -$1.56M | -$2.18M | -$1.59M | -$1.66M | -$732K |
| Acquisitions | $0 | $0 | $0 | $0 | -$24.1M | $16.41M | $0 | -$5.93M | $121.27M | $52K | $0 | $0 | $0 |
| Purchases of Investments | -$192.52M | -$155.49M | -$424.83M | $0 | -$99.9M | -$199.11M | -$174.99M | -$204.6M | -$218.71M | -$121.52M | -$250.9M | $0 | $0 |
| Sales of Investments | $133M | $255.5M | $275M | $100M | $124M | $182.7M | $258.19M | $214.31M | $99M | $169.5M | $122.75M | $0 | $0 |
| Other Investing Activities | $0 | $0 | $0 | $0 | $24.1M | -$16.41M | $0 | $5.93M | -$121.27M | $52K | -$817K | $0 | $0 |
| Net Cash from Investing | -$59.74M | $99.7M | -$150.67M | $98.26M | $22.49M | -$18.72M | $79.7M | $5.93M | -$121.27M | $45.86M | -$130.56M | -$1.66M | -$732K |
| Financing Activities | |||||||||||||
| Debt Repaid | - | - | - | - | - | - | - | - | - | -$78K | $3.07M | $1.26M | -$2.63M |
| Common Stock Issuance | $110.45M | $6.91M | $30.23M | $648K | $107.71M | $11.29M | $0 | $134.6M | $19.96M | $159K | $81.78M | $0 | $0 |
| Common Stock Repurchases | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Dividends Paid | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | -$6.71M | $0 | $0 |
| Other Financing Activities | $0 | $613K | $0 | $0 | $2.5M | $5.61M | $1.63M | $5.03M | $3.84M | $918K | $6.97M | $8K | $62K |
| Net Cash from Financing | $110.45M | $7.52M | $30.23M | $648K | $110.21M | $16.89M | $1.63M | $139.62M | $23.8M | $996K | $153.4M | $25.55M | $2.7M |
| Forex Effect | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | -$24.89M | $20.99M | -$176.48M | -$11.88M | $13.67M | $3.43M | -$59.15M | $70.03M | $72.9M | $44.82M | -$4.57M | $55.69M | -$6.04M |
| Supplementary Data | |||||||||||||
| Operating Cash Flow | -$75.59M | -$86.23M | -$56.03M | -$110.79M | -$119.03M | $5.26M | -$140.48M | -$75.52M | $170.37M | -$2.03M | -$27.41M | $31.8M | -$8.01M |
| Capital Expenditure | -$220K | -$310K | -$840K | -$1.74M | -$1.61M | -$2.31M | -$3.5M | -$3.79M | -$1.56M | -$2.18M | -$1.59M | -$1.66M | -$732K |
| Free Cash Flow | -$75.81M | -$86.54M | -$56.88M | -$112.53M | -$120.64M | $2.95M | -$143.98M | -$79.31M | $168.81M | -$4.21M | -$29.01M | $30.14M | -$8.74M |
| Cash at Beginning | $39.08M | $18.09M | $193.65M | $206.45M | $192.78M | $189.34M | $248.49M | $178.47M | $104.64M | $59.82M | $64.4M | $8.7M | $14.75M |
| Cash at End | $14.19M | $39.08M | $17.17M | $194.57M | $206.45M | $192.78M | $189.34M | $248.49M | $177.55M | $104.64M | $59.82M | $64.4M | $8.7M |