CYPHERPUNK TECHNOLOGIES INC. (CYPH)
Cypherpunk Technologies Inc. is a privacy-focused technology company that combines a digital asset treasury strategy centered on Zcash (ZEC) with the development of novel cancer therapies through its subsidiary. The company's mission is to advance technologies that guarantee privacy for individuals on the internet, with a primary focus on investing in, accelerating the adoption of, and strengthening the ecosystem of Zcash, a privacy-preserving digital currency.
Sector: Pharmaceutical Preparations
Industry: Asset Management
Cypherpunk Technologies Inc.
Trials need funding. See this company's dilution risk and cash position.
- Phase 2Completed
A Study of DKN-01 as a Monotherapy or in Combination With Paclitaxel in Patients With Recurrent Epithelial Endometrial or Epithelial Ovarian Cancer or Carcinosarcoma
Paclitaxel, 300mg DKN-01
Endometrial Cancer, Uterine Cancer +2
NCT03395080Enrollment111StartMar 2018Primary CompletionSep 2020CompletionJan 2021 - Phase 2Terminated
A Study of DKN-01 in Combination With Tislelizumab ± Chemotherapy in Patients With Gastric or Gastroesophageal Cancer
DKN-01 300mg, DKN-01 600mg
Gastric Cancer, Gastric Adenocarcinoma +1
NCT04363801Enrollment247StartJul 2020Primary CompletionMar 2025CompletionMar 2025 - Phase 2Completed
Phase 2 Study of DKN-01 in Colorectal Cancer
DKN-01, FOLFIRI
Colorectal Cancer, Colorectal Adenocarcinoma +2
NCT05480306Enrollment188StartAug 2022Primary CompletionJul 2025CompletionJul 2025 - Phase 1Completed
Trial of TRX518 (Anti-GITR mAb) in Stage III or IV Malignant Melanoma or Other Solid Tumors
TRX518
Unresectable Stage III or Stage IV Malignant Melanoma or Other Solid Tumor Malignancies
NCT01239134Enrollment10StartOct 2010Primary CompletionSep 2018CompletionSep 2018 - Phase 1Completed
A Study of DKN-01 in Multiple Myeloma or Advanced Solid Tumors
DKN-01
Multiple Myeloma, Solid Tumors +1
NCT01457417Enrollment32StartJan 2012Primary CompletionDec 2013CompletionDec 2013 - Phase 1Completed
A Study of DKN-01 and Lenalidomide/Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
DKN-01 300 mg, DKN-01 600 mg
Multiple Myeloma
NCT01711671Enrollment8StartMay 2013Primary CompletionJul 2015CompletionJul 2015 - Phase 1Completed
A Study of DKN-01 in Combination With Paclitaxel or Pembrolizumab
DKN-01 150 mg, Paclitaxel
Esophageal Neoplasms, Adenocarcinoma of the Gastroesophageal Junction +3
NCT02013154Enrollment151StartMay 2014Primary CompletionJul 2019CompletionJan 2021 - Phase 1Completed
Study of DKN-01 and Gemcitabine/Cisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic Biliary System or Gallbladder
DKN-01, gemcitabine
Carcinoma of Intrahepatic and Extra-hepatic Biliary System, Carcinoma of Gallbladder +2
NCT02375880Enrollment51StartJun 2015Primary CompletionJul 2018CompletionJul 2018 - Phase 1Completed
Phase 1 Open-label Study of TRX518 Monotherapy and TRX518 in Combination With Gemcitabine, Pembrolizumab, or Nivolumab
TRX518 monotherapy, TRX518 with gemcitabine
Solid Tumors
NCT02628574Enrollment109StartJan 2016Primary CompletionJul 2020CompletionJul 2020 - Phase 1Terminated
A Dose Escalation and Expansion Study of TRX518 in Combination With Cyclophosphamide Plus Avelumab in Advanced Solid Tumors
TRX518, Cyclophosphamide
Solid Tumors, Advanced Triple Negative Breast Cancer +3
NCT03861403Enrollment10StartMay 2019Primary CompletionJul 2020CompletionJul 2020 - Expanded accessNo longer available
Expanded Access Use of DKN-01 for the Treatment of Advanced Solid Tumors
DKN-01
Esophageal Neoplasm, Adenocarcinoma of the Gastroesophageal Junction +8
NCT04681248Enrollment-Start-Primary Completion-Completion-
| Drug / Therapy | Link | ||
|---|---|---|---|
| Phase 2 | Completed | Paclitaxel, 300mg DKN-01 | NCT03395080 |
| Phase 2 | Terminated | DKN-01 300mg, DKN-01 600mg | NCT04363801 |
| Phase 2 | Completed | DKN-01, FOLFIRI | NCT05480306 |
| Phase 1 | Completed | TRX518 | NCT01239134 |
| Phase 1 | Completed | DKN-01 | NCT01457417 |
| Phase 1 | Completed | DKN-01 300 mg, DKN-01 600 mg | NCT01711671 |
| Phase 1 | Completed | DKN-01 150 mg, Paclitaxel | NCT02013154 |
| Phase 1 | Completed | DKN-01, gemcitabine | NCT02375880 |
| Phase 1 | Completed | TRX518 monotherapy, TRX518 with gemcitabine | NCT02628574 |
| Phase 1 | Terminated | TRX518, Cyclophosphamide | NCT03861403 |
| Expanded access | No longer available | DKN-01 | NCT04681248 |