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Guardant Health, Inc. (GH)

Guardant Health, Inc., established in Redwood City, California, in 2011, is a precision oncology company that delivers a range of diagnostic blood tests, comprehensive data sets, and advanced analytical solutions both within the United States and internationally. For patients with advanced-stage cancer, the company's core offerings include several liquid biopsy-based tests such as Guardant360 (available in LDT and CDx versions) and GuardantOMNI. Complementing these diagnostic tools, Guardant Health also provides GuardantINFORM, an in-silico research platform leveraging an extensive clinical-genomic liquid biopsy dataset derived from advanced cancer patients. Innovation is a key focus, with the company currently developing the LUNAR-2 test, designed for the early detection of colorectal cancer in eligible asymptomatic individuals. Another emerging solution in development is GuardantConnect, an integrated software platform intended to link biopharmaceutical and clinical clients by connecting patients whose Guardant360 tests reveal actionable alterations with potentially relevant clinical trials. Furthermore, Guardant Health offers the Guardant Reveal Test, which aids in selecting neoadjuvant and adjuvant treatments for early-stage cancer patients. Its portfolio also includes a Guardant360 product for tissue genotyping and Guardant-19 for novel coronavirus detection. The company extends its expertise to biopharmaceutical companies and medical institutions through various development services, encompassing companion diagnostic development, regulatory approval support, clinical study management (including setup, monitoring, and maintenance), testing development, and kit fulfillment.

Sector: Services-Medical Laboratories

Industry: Medical - Diagnostics & Research

Guardant Health, Inc. logo

Guardant Health, Inc.

NASDAQ:GHHealthcare
-3.51%$178.80
AH$178.00-0.45%vs close
Mkt Cap$23.99B
Float126.96M
O/S134.2M
Vol
$ Vol
RVOL
Inst Own99.8%
SI9.2%
Earnings
Dilution
Phase Distribution
10 lead-sponsored trials·5 active·3 completed
Not applicable10
(17 more as collaborator)
Status Overview
Not yet recruiting1
Recruiting3
Active, not recruiting2
Completed3
Stopped1

Trials need funding. See this company's dilution risk and cash position.

Clinical Trials
Sponsor role
Status
  • Observational
    Terminated

    Registry of Guardant360® Use and Outcomes In People With Advanced Cancer

    -

    Non-small Cell Lung Cancer Metastatic

    Enrollment
    311
    Start
    Apr 2018
    Primary Completion
    Sep 2019
    Completion
    Sep 2019
    NCT03477474
  • Observational
    Completed

    Noninvasive vs. Invasive Lung Evaluation

    Guardant360

    Non-Small Cell Lung Cancer

    Enrollment
    306
    Start
    Feb 2016
    Primary Completion
    Nov 2020
    Completion
    Nov 2020
    NCT03615443
  • Observational
    Completed

    Guardant360® Test-Related Clinical Outcomes in Patients Who Share Medical Records

    -

    Non-Hematologic Malignancy

    Enrollment
    30
    Start
    Apr 2019
    Primary Completion
    Feb 2020
    Completion
    Apr 2020
    NCT03625557
  • Observational
    Active, not recruiting

    Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode

    -

    Colorectal Cancer

    Enrollment
    44,467
    Start
    Oct 2019
    Primary Completion
    Mar 2024
    Completion
    Aug 2027est.
    NCT04136002
  • Observational
    Completed

    Guardant360® Related Clinical Outcomes in Patients Who Share Medical Records-Breast Cancer

    Guardant360 test

    Advanced Breast Cancer

    Enrollment
    109
    Start
    Jul 2020
    Primary Completion
    Mar 2022
    Completion
    Mar 2022
    NCT04436393
  • Observational
    Recruiting

    ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

    Guardant Reveal

    Bladder Carcinoma, Ureter Carcinoma +15

    Enrollment
    2,285
    Start
    Sep 2021
    Primary Completion
    Aug 2030est.
    Completion
    Aug 2030est.
    NCT05059444
  • Observational
    Active, not recruiting

    Screening for High Frequency Malignant Disease

    Low-dose CT scan

    Lung Cancer

    Enrollment
    12,000
    Start
    Jan 2022
    Primary Completion
    Dec 2026est.
    Completion
    Dec 2026est.
    NCT05117840
  • Observational
    Recruiting

    SIBYL: obServation of Therapy Response With lIquid BiopsY evaLuation

    Guardant360

    Non-small Cell Lung Cancer, Colorectal Cancer +1

    Enrollment
    470
    Start
    Oct 2023
    Primary Completion
    Dec 2030est.
    Completion
    Dec 2030est.
    NCT05935384
  • Observational
    Recruiting

    Shield Post-Approval Study Protocol

    Shield Blood Test for colo-rectal cancer Screening

    Colo-rectal Cancer

    Enrollment
    3,375
    Start
    Jul 2025
    Primary Completion
    Sep 2030est.
    Completion
    Dec 2030est.
    NCT06880055
  • Observational
    Not yet recruiting

    Decision Counseling and Follow-up for Shield+ Patients

    Decision Counseling Session

    Colo-rectal Cancer

    Enrollment
    350
    Start
    Jun 2026est.
    Primary Completion
    Dec 2027est.
    Completion
    Jun 2028est.
    NCT07620535