Guardant Health, Inc. (GH)
Guardant Health, Inc., established in Redwood City, California, in 2011, is a precision oncology company that delivers a range of diagnostic blood tests, comprehensive data sets, and advanced analytical solutions both within the United States and internationally. For patients with advanced-stage cancer, the company's core offerings include several liquid biopsy-based tests such as Guardant360 (available in LDT and CDx versions) and GuardantOMNI. Complementing these diagnostic tools, Guardant Health also provides GuardantINFORM, an in-silico research platform leveraging an extensive clinical-genomic liquid biopsy dataset derived from advanced cancer patients. Innovation is a key focus, with the company currently developing the LUNAR-2 test, designed for the early detection of colorectal cancer in eligible asymptomatic individuals. Another emerging solution in development is GuardantConnect, an integrated software platform intended to link biopharmaceutical and clinical clients by connecting patients whose Guardant360 tests reveal actionable alterations with potentially relevant clinical trials. Furthermore, Guardant Health offers the Guardant Reveal Test, which aids in selecting neoadjuvant and adjuvant treatments for early-stage cancer patients. Its portfolio also includes a Guardant360 product for tissue genotyping and Guardant-19 for novel coronavirus detection. The company extends its expertise to biopharmaceutical companies and medical institutions through various development services, encompassing companion diagnostic development, regulatory approval support, clinical study management (including setup, monitoring, and maintenance), testing development, and kit fulfillment.
Sector: Services-Medical Laboratories
Industry: Medical - Diagnostics & Research
Guardant Health, Inc.
Trials need funding. See this company's dilution risk and cash position.
- ObservationalTerminated
Registry of Guardant360® Use and Outcomes In People With Advanced Cancer
-
Non-small Cell Lung Cancer Metastatic
NCT03477474Enrollment311StartApr 2018Primary CompletionSep 2019CompletionSep 2019 - ObservationalCompleted
Noninvasive vs. Invasive Lung Evaluation
Guardant360
Non-Small Cell Lung Cancer
NCT03615443Enrollment306StartFeb 2016Primary CompletionNov 2020CompletionNov 2020 - ObservationalCompleted
Guardant360® Test-Related Clinical Outcomes in Patients Who Share Medical Records
-
Non-Hematologic Malignancy
NCT03625557Enrollment30StartApr 2019Primary CompletionFeb 2020CompletionApr 2020 - ObservationalActive, not recruiting
Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode
-
Colorectal Cancer
NCT04136002Enrollment44,467StartOct 2019Primary CompletionMar 2024CompletionAug 2027est. - ObservationalCompleted
Guardant360® Related Clinical Outcomes in Patients Who Share Medical Records-Breast Cancer
Guardant360 test
Advanced Breast Cancer
NCT04436393Enrollment109StartJul 2020Primary CompletionMar 2022CompletionMar 2022 - ObservationalRecruiting
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Guardant Reveal
Bladder Carcinoma, Ureter Carcinoma +15
NCT05059444Enrollment2,285StartSep 2021Primary CompletionAug 2030est.CompletionAug 2030est. - ObservationalActive, not recruiting
Screening for High Frequency Malignant Disease
Low-dose CT scan
Lung Cancer
NCT05117840Enrollment12,000StartJan 2022Primary CompletionDec 2026est.CompletionDec 2026est. - ObservationalRecruiting
SIBYL: obServation of Therapy Response With lIquid BiopsY evaLuation
Guardant360
Non-small Cell Lung Cancer, Colorectal Cancer +1
NCT05935384Enrollment470StartOct 2023Primary CompletionDec 2030est.CompletionDec 2030est. - ObservationalRecruiting
Shield Post-Approval Study Protocol
Shield Blood Test for colo-rectal cancer Screening
Colo-rectal Cancer
NCT06880055Enrollment3,375StartJul 2025Primary CompletionSep 2030est.CompletionDec 2030est. - ObservationalNot yet recruiting
Decision Counseling and Follow-up for Shield+ Patients
Decision Counseling Session
Colo-rectal Cancer
NCT07620535Enrollment350StartJun 2026est.Primary CompletionDec 2027est.CompletionJun 2028est.
| Drug / Therapy | Link | ||
|---|---|---|---|
| Observational | Terminated | - | NCT03477474 |
| Observational | Completed | Guardant360 | NCT03615443 |
| Observational | Completed | - | NCT03625557 |
| Observational | Active, not recruiting | - | NCT04136002 |
| Observational | Completed | Guardant360 test | NCT04436393 |
| Observational | Recruiting | Guardant Reveal | NCT05059444 |
| Observational | Active, not recruiting | Low-dose CT scan | NCT05117840 |
| Observational | Recruiting | Guardant360 | NCT05935384 |
| Observational | Recruiting | Shield Blood Test for colo-rectal cancer Screening | NCT06880055 |
| Observational | Not yet recruiting | Decision Counseling Session | NCT07620535 |