Genprex, Inc. (GNPX)
Genprex, Inc. is a biotechnology firm specializing in gene therapy, with its primary focus on advancing treatments through clinical stages. Their mission revolves around developing innovative therapies for patients battling cancer and diabetes. Leading their product pipeline is REQORSA (GPX-001), a flagship gene therapy candidate specifically designed to target both non-small cell lung cancer and small cell lung cancer. In addition, Genprex is progressing GPX-002, another gene therapy at the preclinical stage, intended for the management of diabetes. The company was established in 2009 and operates from its corporate headquarters located in Austin, Texas.
Sector: Pharmaceutical Preparations
Industry: Biotechnology
Genprex, Inc.
Trials need funding. See this company's dilution risk and cash position.
- Phase 1/2Terminated
TUSC2-nanoparticles and Erlotinib in Stage IV Lung Cancer
DOTAP:Chol-TUSC2, Erlotinib
Lung Cancer
NCT01455389Enrollment25StartFeb 2014Primary CompletionOct 2016CompletionSep 2020 - Phase 1/2Recruiting
Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib
quaratusugene ozeplasmid, osimertinib
Carcinoma, Non-Small Cell Lung
NCT04486833Enrollment158StartSep 2021Primary CompletionMar 2028est.CompletionMar 2029est. - Phase 1/2Recruiting
Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients
quaratusugene ozeplasmid, atezolizumab
Small Cell Lung Cancer Extensive Stage
NCT05703971Enrollment62StartMay 2024Primary CompletionDec 2027est.CompletionJun 2028est. - Phase 1Terminated
Quaratusugene Ozeplasmid (Reqorsa) in Combination With Pembrolizumab in Previously Treated Non-Small Lung Cancer
quaratusugene ozeplasmid, pembrolizumab
Non Small Cell Lung Cancer
NCT05062980Enrollment5StartMar 2022Primary CompletionFeb 2025CompletionFeb 2025
| Drug / Therapy | Link | ||
|---|---|---|---|
| Phase 1/2 | Terminated | DOTAP:Chol-TUSC2, Erlotinib | NCT01455389 |
| Phase 1/2 | Recruiting | quaratusugene ozeplasmid, osimertinib | NCT04486833 |
| Phase 1/2 | Recruiting | quaratusugene ozeplasmid, atezolizumab | NCT05703971 |
| Phase 1 | Terminated | quaratusugene ozeplasmid, pembrolizumab | NCT05062980 |