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INTEGRA LIFESCIENCES HOLDINGS CORP (IART)

Integra LifeSciences Holdings Corporation is a medical technology company focused on the creation, production, and global distribution of advanced surgical implants and instruments. These products are utilized across various medical fields, including neurosurgery, limb reconstruction, and general surgical procedures. The company operates through two primary business segments: Codman Specialty Surgical and Tissue Technologies. The Codman Specialty Surgical division offers a comprehensive range of neurosurgical and neuro-critical care products. This includes specialized equipment for tissue ablation, dural repair solutions, cerebral spinal fluid management systems, intracranial monitoring tools, and cranial stabilization devices. Additionally, this segment provides surgical headlamps, various instrumentation, and supports these offerings with asset management software, technical assistance, and after-market services. Integra also supplies an extensive catalog of approximately 40,000 surgical instrument designs, along with a wide selection of surgical and lighting products. Its clientele spans hospitals, surgical centers, and extends to dental, podiatry, and veterinary practices. The Tissue Technologies segment specializes in innovative regenerative technology products for the treatment of both acute and chronic wounds. It further provides surgical tissue repair solutions for a multitude of applications, such as hernia repair, peripheral nerve protection and regeneration, and tendon reconstruction. This encompasses a broad array of offerings for skin and wound repair, plastic and reconstructive surgery products, bone grafting materials, and specialized nerve and tendon repair products. Integra LifeSciences distributes its diverse product portfolio internationally, reaching markets throughout the United States, Europe, Asia Pacific, and other global regions. Distribution is managed directly through its dedicated sales forces and various other channels, serving a wide array of healthcare entities including hospitals, integrated health networks, group purchasing organizations, individual clinicians, surgery centers, and other healthcare providers. Founded in 1989, Integra LifeSciences Holdings Corporation is headquartered in Princeton, New Jersey.

Sector: Surgical & Medical Instruments & Apparatus

Industry: Medical - Devices

Integra LifeSciences Holdings Corporation logo

Integra LifeSciences Holdings Corporation

NASDAQ:IARTHealthcare
-0.62%$12.75
AH$12.50-1.96%vs close
Mkt Cap$991.96M
Float66.62M
O/S77.8M
Vol
$ Vol
RVOL
Inst Own94.2%
SI11.0%
Earnings
Dilution
Integra LifeSciences Holdings Corporation logoNASDAQ:IART$12.75-0.62%
Phase Distribution
82 lead-sponsored trials·5 active·49 completed
Phase 2/31
Phase 35
Phase 41
Not applicable75
(25 more as collaborator)
Status Overview
Not yet recruiting1
Recruiting4
Active, not recruiting1
Completed49
Stopped27

Trials need funding. See this company's dilution risk and cash position.

Clinical Trials
Sponsor role
Status
Phase
  • Phase 4
    Completed

    PleuraSeal Post Market Study (Europe)

    Standard Tissue Closure Techniques, PleuraSeal Lung Sealant System

    Lung Disease, Pulmonary Lobectomy

    Enrollment
    121
    Start
    Jan 2008
    Primary Completion
    Dec 2008
    Completion
    Dec 2008
    NCT00704171
  • Phase 3
    Completed

    Clinical Evaluation to Confirm Safety and Efficacy of Sinuplasty in the Paranasal Sinuses (CLEAR)

    Sinuplasty

    Chronic Sinusitis

    Enrollment
    115
    Start
    Apr 2005
    Primary Completion
    Jun 2006
    Completion
    Jun 2006
    NCT00231062
  • Phase 3
    Terminated

    PleuraSeal Pivotal Study (US)

    PleuraSeal Sealant System, Standard Tissue Closure Techniques

    Open Thoracotomy

    Enrollment
    230
    Start
    Aug 2008
    Primary Completion
    Sep 2010
    Completion
    Apr 2011
    NCT00748124
  • Phase 3
    Terminated

    Phase III Study to Evaluate Efficacy and Safety of DSC127 in Diabetic Foot Ulcers

    DSC127, placebo vehicle gel

    Diabetic Foot Ulcers

    Enrollment
    266
    Start
    Feb 2013
    Primary Completion
    Dec 2015
    Completion
    Dec 2015
    NCT01830348
  • Phase 3
    Terminated

    Open-Label Study in Diabetic Foot Ulcers (DFU), to Evaluate Safety of 0.03% DSC127 Topical Gel in Chronic Use

    0.03% DSC127 topical gel

    Diabetic Foot Ulcer

    Enrollment
    261
    Start
    Dec 2015
    Primary Completion
    Dec 2015
    Completion
    Dec 2015
    NCT01840085
  • Phase 3
    Terminated

    Phase 3 Study Evaluating Efficacy and Safety of DSC127 Compared With Vehicle and With Standard-of-care in Diabetic Foot Ulcers

    DSC127, placebo vehicle gel

    Diabetic Foot Ulcers

    Enrollment
    396
    Start
    Apr 2013
    Primary Completion
    Dec 2015
    Completion
    Dec 2015
    NCT01849965
  • Phase 2/3
    Completed

    Evaluation of the Tympanostomy Tube Delivery System

    tympanostomy tube

    Otitis Media With Effusion, Acute Otitis Media

    Enrollment
    53
    Start
    Sep 2010
    Primary Completion
    Nov 2010
    Completion
    Dec 2010
    NCT01202578
  • Not applicable
    Terminated

    DuraGen Plus® Adhesion Barrier for Use in Spinal Surgery

    DuraGen Plus Adhesion Barrier Matrix

    Spinal Injuries, Adhesions

    Enrollment
    347
    Start
    Oct 2006
    Primary Completion
    Dec 2010
    Completion
    Dec 2011
    NCT00387829
  • Not applicable
    Terminated

    Study to Evaluate Safety & Effectiveness of Vascular Sealant System

    Gelfoam/Thrombin, VascuSeal

    Peripheral Vascular Disease

    Enrollment
    69
    Start
    Apr 2007
    Primary Completion
    May 2008
    Completion
    May 2008
    NCT00439309
  • Not applicable
    Completed

    Study to Evaluate Safety & Effectiveness of Spinal Sealant

    Spinal Sealant, Standard of Care

    Cerebrospinal Fluid Leakage, Subdural

    Enrollment
    98
    Start
    May 2007
    Primary Completion
    Aug 2009
    Completion
    Aug 2009
    NCT00444067
  • Not applicable
    Completed

    Study to Evaluate Safety and Effectiveness of Spinal Sealant

    Spinal Sealant System, Standard of care

    Spinal Procedure Requiring Dura Incision

    Enrollment
    158
    Start
    Sep 2005
    Primary Completion
    Feb 2008
    Completion
    Apr 2008
    NCT00594035
  • Not applicable
    Completed

    DuraSeal Sealant Post Market Study

    DuraSeal Dural Sealant System, Standard of Care

    Elective Cranial Procedures With Dural Incision

    Enrollment
    237
    Start
    Sep 2005
    Primary Completion
    May 2009
    Completion
    May 2009
    NCT00704340
  • Not applicable
    Completed

    Clinical Study of Safety and Efficacy for the Relieva Stratus With Elution of Triamcinolone Acetonide

    Stratus Microflow Ethmoid Spacer

    Sinusitis

    Enrollment
    63
    Start
    Aug 2008
    Primary Completion
    Nov 2011
    Completion
    Nov 2011
    NCT00791934
  • Not applicable
    Completed

    Post Market Study for an Adhesion Barrier Following Laparoscopic Myomectomy

    SprayShield™

    Fibroid, Myoma +1

    Enrollment
    15
    Start
    Nov 2008
    Primary Completion
    May 2009
    Completion
    May 2009
    NCT00891657
  • Observational
    Completed

    Large Abdominal Hernia Repair With SurgiMend 3.0

    -

    Hernia

    Enrollment
    122
    Start
    Apr 2009
    Primary Completion
    Jul 2014
    Completion
    Jul 2014
    NCT00892333
  • Not applicable
    Completed

    Balloon Sinus Dilation In Office or OR

    FESS instruments with or without balloon treatment, Balloon Sinuplasty

    Chronic Sinusitis

    Enrollment
    72
    Start
    Apr 2008
    Primary Completion
    Jun 2009
    Completion
    Jul 2010
    NCT00939393
  • Not applicable
    Completed

    Safety and Efficacy of Balloon Sinuplasty in Pediatric Sinusitis

    Relieva™ Balloon Sinuplasty™ System

    Chronic Sinusitis

    Enrollment
    44
    Start
    Apr 2007
    Primary Completion
    Jul 2009
    Completion
    May 2010
    NCT00939471
  • Not applicable
    Completed

    Clinical Study of the Tympanostomy Tube Delivery System

    Acclarent Tympanostomy Tube Delivery System

    Otitis Media With Effusion

    Enrollment
    16
    Start
    Mar 2009
    Primary Completion
    Jun 2009
    Completion
    Jul 2009
    NCT00939796
  • Not applicable
    Completed

    Anesthetic Effect of Lidocaine/Epinephrine Solution Delivered Via Iontophoresis to External Auditory Apparatus

    Iontophoresis System (Acclarent)

    Acute Otitis Media, Chronic Otitis Media +1

    Enrollment
    109
    Start
    Apr 2008
    Primary Completion
    Jan 2011
    Completion
    Jan 2011
    NCT00941993
  • Not applicable
    Terminated

    An Evaluation of SprayShield in Reducing Post-Operative Adhesion Formation Following Major Open Abdominal Surgery

    SprayShield Adhesion Barrier System, Good Surgical Technique Alone

    Ulcerative Colitis, Familial Polyposis

    Enrollment
    11
    Start
    Oct 2009
    Primary Completion
    Oct 2010
    Completion
    May 2011
    NCT01002287
  • Not applicable
    Completed

    Singapore Tympanostomy Tube Delivery System Study

    Tympanostomy Tube Delivery System

    Otitis Media

    Enrollment
    25
    Start
    Dec 2008
    Primary Completion
    Aug 2010
    Completion
    Jun 2011
    NCT01046877
  • Not applicable
    Completed

    Anesthetizing the Tympanic Membrane in Healthy Volunteers

    Acclarent Iontophoresis System

    Evaluate Performance and Reliability of Iontophoresis System

    Enrollment
    21
    Start
    Aug 2009
    Primary Completion
    Nov 2009
    Completion
    Nov 2009
    NCT01047904
  • Not applicable
    Terminated

    Clinical Evaluation of the Ethmoid Sinus Spacer

    Ethmoid Sinus Spacer

    Sinusitis, Chronic Rhinosinusitis

    Enrollment
    14
    Start
    Apr 2007
    Primary Completion
    Nov 2007
    Completion
    Nov 2007
    NCT01054703
  • Not applicable
    Completed

    A Safety and Efficacy Study of INTEGRA® Dermal Regeneration Template for the Treatment of Diabetic Foot Ulcers

    Integra® Dermal Regeneration Template, Conventional Wound Therapy

    Neuropathic Diabetic Ulcer - Foot

    Enrollment
    545
    Start
    Apr 2010
    Primary Completion
    Jun 2014
    Completion
    Jun 2014
    NCT01060670
  • Observational
    Completed

    Optimization and Refinement of Technique in In-Office Sinus Dilation 2

    Relieva Balloon Sinuplasty System

    Sinusitis

    Enrollment
    203
    Start
    Apr 2010
    Primary Completion
    Jan 2012
    Completion
    Jul 2012
    NCT01107379

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