InflaRx N.V. (IFRX)
InflaRx N.V. is a clinical-stage biopharmaceutical firm dedicated to discovering and developing novel inhibitors leveraging C5a technology, primarily operating in Germany and the United States. The company's focus on C5a stems from its critical role as an inflammatory mediator implicated in the progression of various autoimmune and inflammatory diseases. Its primary product candidate, vilobelimab, is an innovative, first-in-class anti-C5a monoclonal antibody delivered intravenously. Vilobelimab has progressed through several clinical stages for multiple indications: It has successfully completed a Phase III clinical trial for hidradenitis suppurativa (HS), a rare, chronic, and debilitating systemic inflammatory skin condition. It is currently undergoing Phase II trials for anti-neutrophil cytoplasm antibody associated vasculitis (AAV), a rare and life-threatening autoimmune disorder, and for PD-1/PD-L1 inhibitor resistant/refractory locally advanced or metastatic cutaneous squamous cell carcinoma (CSCC). An exploratory Phase IIa study is also underway for pyoderma gangraenosum (PG), a chronic inflammatory skin disorder. Beyond its lead candidate, InflaRx is also advancing INF904, an oral, small molecule drug candidate targeting undisclosed chronic inflammatory and autoimmune diseases, and IFX002, which is in preclinical development for chronic inflammation and autoimmune conditions. Strategic collaborations include a co-development agreement with Beijing Defengrei Biotechnology Co. Ltd. and a clinical trial collaboration and supply agreement with Merck & Co. Inc. Established in 2007, the company, initially known as Fireman B.V., officially became InflaRx N.V. in 2017. It maintains its headquarters in Jena, Germany, with operations extending to the United States.
Sector: Pharmaceutical Preparations
Industry: Biotechnology
InflaRx N.V.
No splits on record
Nothing in IFRX's public trading history: no forward or reverse split has affected the share count.
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 |
| Revenue | $33K | $185K | $70K | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| YoY Growth | -82.3% | 162.8% | - | - | - | - | - | - | - | - | - |
| Cost of Revenue | $8.12M | $3.71M | $595K | $0 | $0 | $0 | $0 | $201K | $75K | $40K | $46K |
| Gross Profit | -$8.09M | -$3.52M | -$524K | $0 | $0 | $0 | $0 | -$201K | -$76K | -$40K | -$46K |
| Gross Margin | -24677.9% | -1900.8% | -743.7% | - | - | - | - | - | - | - | - |
| Research and Development | $28.74M | $39.51M | $45.83M | $41.92M | $39.88M | $28.69M | $49.81M | $27.96M | $16.1M | $5.9M | $3.89M |
| Selling, General, and Administrative | $19.62M | $21.59M | $18.01M | $16.02M | $12.77M | $8.84M | $13.97M | $14.29M | $5.74M | $2.06M | $489K |
| Other | -$2.53M | -$5.51M | -$14.55M | -$21.93M | $563K | $389K | -$352K | -$334K | -$870K | -$264K | -$150K |
| Total Operating Expenses | $45.83M | $55.59M | $49.3M | $36.02M | $53.22M | $37.92M | $63.42M | $41.91M | $20.97M | $7.69M | $4.23M |
| Operating Income (EBIT) | -$53.91M | -$59.11M | -$49.82M | -$36.02M | -$53.22M | -$37.92M | -$63.42M | -$41.91M | -$21.72M | -$7.7M | -$4.23M |
| Operating Margin | -164525.5% | -31911.4% | -70685.6% | - | - | - | - | - | - | - | - |
| Interest Expense | $42K | $23K | $40K | $51K | $28K | $29K | $25K | $0 | $2.49M | $2.05M | $1.18M |
| Interest Income | $1.98M | $3.57M | $4.25M | $680K | $122K | $992K | $3.17M | $2.44M | $145K | $1K | $6K |
| Other Income (Expense) | $2.94M | $7.65M | $2.15M | $3.08M | $2.24M | -$46K | $3.93M | $8.6M | -$5.35M | -$2.29M | -$1.27M |
| Income Before Tax (EBT) | -$50.97M | -$51.46M | -$47.67M | -$32.94M | -$50.98M | -$37.97M | -$59.5M | -$33.31M | -$27.08M | -$9.99M | -$5.49M |
| Income Tax Expense | $14K | $6K | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Net Income | -$50.98M | -$51.46M | -$47.67M | -$32.94M | -$50.98M | -$37.97M | -$59.5M | -$33.31M | -$27.08M | -$9.99M | -$5.49M |
| Net Income Margin | -155582.1% | -27785.0% | -67630.7% | - | - | - | - | - | - | - | - |
| Supplementary Data | |||||||||||
| EPS | -0.66 | -0.78 | -0.78 | -0.61 | -1.10 | -1.26 | -1.91 | -1.19 | -1.03 | -0.38 | -0.21 |
| Diluted EPS | -0.66 | -0.78 | -0.78 | -0.61 | -1.10 | -1.26 | -1.91 | -1.19 | -1.03 | -0.38 | -0.21 |
| Weighted Average OS | 67.29M | 58.92M | 54.94M | 44.21M | 41.63M | 27.06M | 26.00M | 25.09M | 23.61M | 23.41M | 23.41M |
| EBITDA | -$50.46M | -$50.89M | -$46.99M | -$32.22M | -$50.2M | -$37.12M | -$62.68M | -$41.72M | -$24.51M | -$7.9M | -$4.27M |
| EBITDA Margin | -153976.3% | -27476.7% | -66674.3% | - | - | - | - | - | - | - | - |
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 |
| Assets | |||||||||||
| Current Assets | |||||||||||
| Cash and Cash Equivalents | $17.89M | $20.53M | $14.26M | $18.17M | $29.33M | $29.01M | $37.01M | $61.88M | $137.73M | $32.53M | $3.69M |
| Short-Term Investments | $33.99M | $0 | $0 | $73.22M | $63.86M | $61.63M | $92.01M | $113.04M | $0 | $0 | $0 |
| Cash and Short-Term Investments | $51.88M | $20.53M | $14.26M | $91.4M | $93.19M | $90.64M | $129.02M | $174.92M | $137.73M | $32.53M | $3.69M |
| Accounts Receivable | $1.6M | $0 | $0 | $1.6M | $1.43M | $0 | $0 | $0 | $134K | $0 | $143K |
| Inventory | $0 | $7.71M | $12.7M | $0 | $0 | $0 | $0 | $0 | $563K | $35K | $31K |
| Other Current Assets | $6.42M | $51.42M | $95.03M | $2.85M | $0 | $4.31M | $1.49M | $605K | $82K | $15K | $12K |
| Total Current Assets | $59.89M | $80.05M | $122.3M | $108.83M | $106.89M | $96.4M | $132.93M | $176.7M | $138.51M | $32.82M | $3.88M |
| Long-Term Assets | |||||||||||
| Property, Plant & Equipment Net | $1.29M | $1.13M | $1.52M | $1.83M | $1.88M | $1.07M | $1.58M | $698K | $193K | $146K | $122K |
| Goodwill | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Intangible Assets | $47K | $8K | $48K | $155K | $263K | $391K | $505K | $249K | $46K | $6K | $8K |
| Long-Term Investments | $265K | $3.45M | $10.11M | $3.24M | $30.4M | $304K | $305K | $231K | $22K | $1K | $1K |
| Deferred Tax Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | -$216K | $0 | $0 |
| Other Long-Term Assets | $169K | $277K | $316K | $344K | $376K | $395K | $505K | $0 | $216K | $0 | $0 |
| Total Long-Term Assets | $1.77M | $4.87M | $12M | $5.57M | $32.91M | $2.16M | $2.89M | $1.18M | $261K | $153K | $131K |
| Other Assets | $0 | $0 | $0 | $0 | $1 | $0 | -$2 | $0 | $0 | $0 | $0 |
| Total Assets | $61.66M | $84.93M | $134.3M | $114.4M | $139.81M | $98.55M | $135.83M | $177.87M | $138.77M | $32.98M | $4.01M |
| Liabilities | |||||||||||
| Current Liabilities | |||||||||||
| Accounts Payable | $6.03M | $3.81M | $5.7M | $5.57M | $1.88M | $1.95M | $13.87M | $7.44M | $4.99M | $1.71M | $413K |
| Short-Term Debt | $287K | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Current Income Tax Payable | $0 | $0 | $0 | $0 | $0 | $0 | $118K | $346K | $0 | $0 | $0 |
| Current Unearned Revenue | $0 | $0 | $0 | $6.94M | $9.27M | $0 | $0 | $0 | $17K | $0 | $0 |
| Other Current Liabilities | $6.88M | $337K | $3.22M | -$2.19M | $1.69M | $148K | $1.26M | $1.23M | $333K | $237K | $74K |
| Total Current Liabilities | $14.5M | $15.83M | $18.82M | $14.55M | $20.96M | $11.28M | $15.71M | $8.67M | $5.33M | $1.95M | $487K |
| Long-Term Liabilities | |||||||||||
| Long-Term Debt | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $59.7M | $23.18M |
| Long-Term Unearned Revenue | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $12K | $17K | $21K | $26K |
| Long-Term Deferred Tax Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | -$59.7M | -$23.18M |
| Other Long-Term Liabilities | $41K | $41K | $41K | $41K | $39K | $37K | $44K | $63K | $2K | $23K | $28K |
| Total Long-Term Liabilities | $757K | $487K | $874K | $1.14M | $1.23M | $284K | $413K | $75K | $19K | $59.73M | $23.2M |
| Other Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities | $15.25M | $16.31M | $19.69M | $15.7M | $22.19M | $11.57M | $16.12M | $8.74M | $5.34M | $61.68M | $23.69M |
| Stockholders' Equity | |||||||||||
| Preferred Stock | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Common Stock | $9.69M | $7.96M | $7.89M | $5.99M | $5.93M | $3.78M | $3.5M | $3.48M | $3.19M | $35K | $35K |
| Retained Earnings | -$421.93M | -$371.13M | -$319.66M | -$271.99M | -$239.05M | -$188.08M | -$150.11M | -$90.61M | -$57.3M | -$30.23M | -$20.24M |
| Comprehensive Income & Other | $54.23M | $57.6M | $52.99M | $40.93M | $34.18M | $25.17M | $28.09M | $20.46M | $187.54M | $1.88M | $912K |
| Other Stockholders' Equity | $458.65M | $431.78M | $426.37M | $364.7M | $350.75M | $271.28M | $266.31M | $256.27M | $187.54M | $1.49M | $521K |
| Total Equity | $46.41M | $68.61M | $114.6M | $98.7M | $117.62M | $86.99M | $119.7M | $169.13M | $133.43M | -$28.7M | -$19.68M |
| Minority Interest | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities and Equity | $61.66M | $84.93M | $134.3M | $114.4M | $139.81M | $98.55M | $135.83M | $177.87M | $138.77M | $32.98M | $4.01M |
| Supplementary Data | |||||||||||
| Total Debt | $1M | $899K | $1.25M | $1.52M | $1.6M | $625K | $945K | $0 | $0 | $59.7M | $23.18M |
| Net Debt | -$16.89M | -$19.63M | -$13.01M | -$16.66M | -$27.73M | -$28.39M | -$36.07M | -$61.88M | -$137.73M | $27.17M | $19.49M |
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 |
| Operating Activities | |||||||||||
| Net Income | -$48.97M | -$51.46M | -$47.67M | -$32.94M | -$50.98M | -$37.97M | -$59.5M | -$33.31M | -$27.08M | -$9.99M | -$5.49M |
| Depreciation & Amortization | $469K | $542K | $634K | $667K | $748K | $796K | $741K | $194K | $79K | $37K | $45K |
| Deferred Income Tax | $0 | $0 | $0 | $0 | $1.29M | $1.04M | $0 | -$2.1M | $74K | $0 | $6K |
| Stock-Based Compensation | $0 | $4.54M | $3.81M | $6.75M | $4.84M | $1.25M | $7.63M | $13.5M | $5.08M | $970K | $271K |
| Changes in Working Capital: | |||||||||||
| Accounts Receivable | $2.36M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Inventory | $7.4M | $4.99M | -$12.7M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Accounts Payable | -$6.43M | $0 | $0 | -$3.93M | $353K | -$4.33M | $0 | $2.44M | $3.45M | $1.53M | $435K |
| Other Working Capital | $1.88M | -$7.54M | $13.82M | -$6.98M | $1.37M | -$1.65M | -$2.61M | -$398K | -$563K | $1.35M | -$133K |
| Total Working Capital Change | $5.21M | -$2.55M | $1.12M | -$10.92M | $1.72M | -$5.97M | -$2.61M | $2.05M | $2.88M | $1.35M | $302K |
| Other Non-Cash Items | $5.39M | -$5.32M | -$147K | -$1.26M | -$2.24M | $49K | $5.47M | -$6.82M | $5.38M | $2.05M | $1.17M |
| Net Cash from Operating | -$37.9M | -$54.25M | -$42.24M | -$37.7M | -$44.62M | -$40.81M | -$48.27M | -$26.49M | -$13.58M | -$5.58M | -$3.7M |
| Investing Activities | |||||||||||
| Capital Expenditures | -$124K | -$52K | -$91K | -$181K | -$42K | -$105K | -$665K | -$900K | -$166K | -$59K | -$15K |
| Acquisitions | $0 | $0 | $0 | -$21.81M | $42K | $105K | $0 | $900K | $0 | $0 | $0 |
| Purchases of Investments | -$49.47M | -$39.48M | -$116.25M | -$72.03M | -$108.95M | -$113.51M | $0 | -$119.15M | -$21K | $0 | $0 |
| Sales of Investments | $53.06M | $98.04M | $96.57M | $93.84M | $80M | $137.48M | $0 | $8.95M | $0 | $0 | $0 |
| Other Investing Activities | -$3 | $1 | $0 | $21.81M | -$42K | -$105K | $23.39M | -$903K | $1K | $0 | $0 |
| Net Cash from Investing | $3.47M | $58.5M | -$19.77M | $21.63M | -$28.99M | $23.87M | $22.73M | -$111.11M | -$187K | -$59K | -$15K |
| Financing Activities | |||||||||||
| Debt Repaid | $399K | $434K | $418K | $407K | $403K | $409K | $331K | - | - | - | - |
| Common Stock Issuance | $36.14M | $1.23M | $63.1M | $2.63M | $72.78M | $10.92M | $0 | $59.2M | $101.56M | $36.16M | $0 |
| Common Stock Repurchases | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Dividends Paid | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Financing Activities | $16K | -$362K | -$3.49M | -$53K | -$3.58M | -$260K | $2K | -$3.74M | -$10.18M | $0 | $0 |
| Net Cash from Financing | $35.75M | $432K | $59.2M | $2.16M | $68.79M | $10.25M | -$329K | $55.46M | $121.55M | $34.48M | $0 |
| Forex Effect | -$1.53M | $1.58M | -$1.09M | $2.75M | $5.13M | -$1.31M | $1.01M | $6.29M | -$2.59M | $1K | $1K |
| Net Change in Cash | -$201K | $6.27M | -$3.91M | -$11.15M | $314K | -$8M | -$24.86M | -$75.85M | $105.2M | $28.84M | -$3.71M |
| Supplementary Data | |||||||||||
| Operating Cash Flow | -$37.9M | -$54.25M | -$42.24M | -$37.7M | -$44.62M | -$40.81M | -$48.27M | -$26.49M | -$13.58M | -$5.58M | -$3.7M |
| Capital Expenditure | -$124K | -$52K | -$91K | -$181K | -$42K | -$105K | -$665K | -$900K | -$166K | -$59K | -$15K |
| Free Cash Flow | -$38.02M | -$54.3M | -$42.34M | -$37.88M | -$44.66M | -$40.91M | -$48.93M | -$27.39M | -$13.74M | -$5.64M | -$3.71M |
| Cash at Beginning | $18.09M | $14.26M | $18.17M | $29.33M | $29.01M | $37.01M | $61.88M | $137.73M | $32.53M | $3.69M | $7.4M |
| Cash at End | $17.89M | $20.53M | $14.26M | $18.17M | $29.33M | $29.01M | $37.01M | $61.88M | $137.73M | $32.53M | $3.69M |