Karyopharm Therapeutics Inc. (KPTI)
Karyopharm Therapeutics Inc. (KPTI) Insider Trading
Directors, officers and holders of more than 10% of KPTI report their trades in its stock on SEC Form 4, within two business days. Each row below is one Form 4 transaction line. The one-letter code says what kind of transaction it was: only P (purchase) and S (sale) are open-market or private trades; awards, option exercises, tax withholding and gifts carry other codes.
Recent Form 4 transactions
The 50 most recent of 110 transactions on file: 0 with code P, 25 with code S and 25 with other codes.
| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Oct 16, 2026 | Abate Kristin | Chief Accounting Officer | S Sale | 4,788 | $0.3440 | $1,647 |
| Oct 1, 2026 | Abate Kristin | Chief Accounting Officer | S Sale | 378 | $1.19 | $450 |
| Sep 1, 2026 | Abate Kristin | Chief Accounting Officer | S Sale | 19 | $2.02 | $38 |
| Jul 28, 2026 | Poulton Stuart | EVP, Chief Development Officer | S Sale | 189 | $7.10 | $1,342 |
| May 21, 2026 | Su Zhen | Director | A Award | 15,508 | Not measured | Not measured |
| May 21, 2026 | BOHLIN GAREN G | Director | A Award | 15,508 | Not measured | Not measured |
| May 21, 2026 | Schor Chen | Director | A Award | 15,508 | Not measured | Not measured |
| May 21, 2026 | PAKIANATHAN DEEPIKA | Director | A Award | 15,508 | Not measured | Not measured |
| May 21, 2026 | Oliger Christy J. | Director | A Award | 15,508 | Not measured | Not measured |
| May 21, 2026 | Greene Barry E | Director | A Award | 15,508 | Not measured | Not measured |
| May 14, 2026 | Rangwala Reshma | EVP & Chief Medical Officer | S Sale | 408 | $9.50 | $3,876 |
| May 14, 2026 | Abate Kristin | Chief Accounting Officer | S Sale | 53 | $9.50 | $504 |
| May 14, 2026 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | S Sale | 324 | $9.50 | $3,078 |
| May 14, 2026 | Mano Michael | EVP, CLO&Secretary | S Sale | 266 | $9.50 | $2,527 |
| May 14, 2026 | Poulton Stuart | EVP, Chief Development Officer | S Sale | 403 | $9.50 | $3,829 |
| May 14, 2026 | Paulson Richard A. | President and CEO | S Sale | 2,203 | $9.50 | $20,929 |
| May 13, 2026 | Rangwala Reshma | EVP & Chief Medical Officer | A Award | 947 | Not measured | Not measured |
| May 13, 2026 | Abate Kristin | Chief Accounting Officer | A Award | 121 | Not measured | Not measured |
| May 13, 2026 | Paulson Richard A. | President and CEO | A Award | 4,920 | Not measured | Not measured |
| May 13, 2026 | Mano Michael | EVP, CLO&Secretary | A Award | 700 | Not measured | Not measured |
| May 13, 2026 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | A Award | 947 | Not measured | Not measured |
| May 13, 2026 | Poulton Stuart | EVP, Chief Development Officer | A Award | 896 | Not measured | Not measured |
| Apr 21, 2026 | Rangwala Reshma | EVP & Chief Medical Officer | S Sale | 449 | $8.94 | $4,014 |
| Mar 2, 2026 | Rangwala Reshma | EVP & Chief Medical Officer | S Sale | 5,066 | $9.41 | $47,669 |
| Mar 2, 2026 | Abate Kristin | Chief Accounting Officer | S Sale | 559 | $9.41 | $5,260 |
| Mar 2, 2026 | Paulson Richard A. | President and CEO | S Sale | 12,361 | $9.41 | $116,311 |
| Mar 2, 2026 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | S Sale | 4,604 | $9.41 | $43,321 |
| Mar 2, 2026 | Poulton Stuart | EVP, Chief Development Officer | S Sale | 5,101 | $9.41 | $47,998 |
| Mar 2, 2026 | Mano Michael | EVP, CLO&Secretary | S Sale | 3,526 | $9.41 | $33,178 |
| Feb 17, 2026 | Poulton Stuart | EVP, Chief Development Officer | S Sale | 378 | $8.63 | $3,262 |
| Feb 5, 2026 | Paulson Richard A. | President and CEO | A Award | 81,060 | Not measured | Not measured |
| Feb 3, 2026 | Macomber Lori | EVP, CFO & Treasurer | S Sale | 1,626 | $6.30 | $10,244 |
| Jan 31, 2026 | Mano Michael | EVP, CLO&Secretary | A Award | 32,415 | Not measured | Not measured |
| Jan 31, 2026 | Rangwala Reshma | EVP & Chief Medical Officer | A Award | 32,415 | Not measured | Not measured |
| Jan 31, 2026 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | A Award | 32,415 | Not measured | Not measured |
| Jan 31, 2026 | Poulton Stuart | EVP, Chief Development Officer | A Award | 32,415 | Not measured | Not measured |
| Jan 31, 2026 | Macomber Lori | EVP, CFO & Treasurer | A Award | 32,415 | Not measured | Not measured |
| Jan 28, 2026 | Abate Kristin | Chief Accounting Officer | S Sale | 50 | $7.03 | $352 |
| Jan 27, 2026 | Abate Kristin | Chief Accounting Officer | A Award | 92 | Not measured | Not measured |
| Jan 21, 2026 | Abate Kristin | Chief Accounting Officer | S Sale | 265 | $5.96 | $1,579 |
| Oct 15, 2025 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | A Award | 43,650 | Not measured | Not measured |
| Oct 15, 2025 | Mano Michael | EVP, CLO&Secretary | A Award | 43,650 | Not measured | Not measured |
| Oct 15, 2025 | Paulson Richard A. | President and CEO | A Award | 114,285 | Not measured | Not measured |
| Oct 15, 2025 | Poulton Stuart | EVP, Chief Development Officer | A Award | 39,682 | Not measured | Not measured |
| Oct 15, 2025 | Macomber Lori | EVP, CFO & Treasurer | A Award | 43,650 | Not measured | Not measured |
| Oct 15, 2025 | Abate Kristin | Chief Accounting Officer | A Award | 12,799 | Not measured | Not measured |
| Oct 1, 2025 | Abate Kristin | Chief Accounting Officer | S Sale | 362 | $6.30 | $2,279 |
| Sep 15, 2025 | Poulton Stuart | EVP, Chief Development Officer | S Sale | 401 | $6.43 | $2,578 |
| Sep 15, 2025 | Mano Michael | EVP, CLO&Secretary | S Sale | 234 | $6.43 | $1,505 |
| Sep 15, 2025 | Abate Kristin | Chief Accounting Officer | S Sale | 23 | $6.43 | $148 |
The full Form 4 history is on the KPTI company page (Insider Trades card, View all).
Questions about this data
Which insider transactions are open-market trades?
Code P (open market or private purchase) and code S (open market or private sale). Code F is shares withheld to pay tax on vesting stock, A is an award from the company, M and X are option exercises and G is a gift. None of those is the insider choosing to buy or sell in the market.
How quickly are insider trades reported?
A Form 4 is due before the end of the second business day after the trade. The date shown is the transaction date from the form.
Who has to file Form 4?
Officers, directors and beneficial owners of more than 10% of a class of the company’s registered equity, under Section 16 of the Securities Exchange Act.
Look up any code in the Form 4 transaction code reference, or read Form 4 codes explained.