Nanobiotix S.A. (NBTX)
Nanobiotix S.A. is a clinical-stage biotechnology firm focused on developing innovative therapeutic solutions for cancer. The company's leading experimental drug, NBTXR3, is a sterile aqueous suspension comprising crystalline hafnium oxide nanoparticles. This treatment is currently undergoing development for its potential application in a broad spectrum of cancers, including soft tissue sarcoma, various head and neck cancers, liver cancers, prostate cancer, pancreatic cancer, esophageal cancer, rectal cancer, and non-small cell lung cancer. Nanobiotix S.A. has established a strategic collaboration with LianBio for the development and commercialization of NBTXR3 within key Asian markets, specifically Greater China, South Korea, Singapore, and Thailand. Founded in 2003, the company's main operations are situated in Paris, France.
Sector: Pharmaceutical Preparations
Industry: Biotechnology
Nanobiotix S.A.
Trials need funding. See this company's dilution risk and cash position.
- Phase 2/3Completed
NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating Randomized Patients in Two Arms With Soft Tissue Sarcoma of the Extremity and Trunk Wall
NBTXR3, Radiation therapy
Adult Soft Tissue Sarcoma
NCT02379845Enrollment180StartMar 2015Primary CompletionMay 2018CompletionSep 2020 - Phase 1/2Terminated
NBTXR3 Crystalline Nanoparticles and Stereotactic Body Radiation Therapy in the Treatment of Liver Cancers
NBTXR3, IL or IA injection + SBRT
Liver Cancer
NCT02721056Enrollment23StartJan 2016Primary CompletionMay 2020CompletionMay 2020 - Phase 1/2Terminated
NBTXR3 Nanoparticles and EBRT or EBRT With Brachytherapy in the Treatment of Prostate Adenocarcinoma
NBTXR3 activated by IMRT only, NBTXR3 activated by Brachytherapy & IMRT
Prostate Cancer
NCT02805894Enrollment5StartNov 2017Primary CompletionMar 2020CompletionMar 2020 - Phase 1Completed
NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma of the Extremity
NBTXR3
Adult Soft Tissue Sarcoma
NCT01433068Enrollment22StartOct 2011Primary CompletionMay 2014CompletionFeb 2015 - Phase 1Active, not recruiting
NBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 Therapy
NBTXR3, Nivolumab
Radiotherapy, Immunotherapy +9
NCT03589339Enrollment145StartJan 2019Primary CompletionApr 2027est.CompletionAug 2027est. - Not applicableUnknown status
NBTXR3 and Radiation Therapy in Treating Patients With Locally Advanced SCC of the Oral Cavity or Oropharynx
NBTXR3 activated by IMRT
Head and Neck Cancer
NCT01946867Enrollment75StartJan 2014Primary CompletionFeb 2023est.CompletionFeb 2023est.
| Drug / Therapy | Link | ||
|---|---|---|---|
| Phase 2/3 | Completed | NBTXR3, Radiation therapy | NCT02379845 |
| Phase 1/2 | Terminated | NBTXR3, IL or IA injection + SBRT | NCT02721056 |
| Phase 1/2 | Terminated | NBTXR3 activated by IMRT only, NBTXR3 activated by Brachytherapy & IMRT | NCT02805894 |
| Phase 1 | Completed | NBTXR3 | NCT01433068 |
| Phase 1 | Active, not recruiting | NBTXR3, Nivolumab | NCT03589339 |
| Not applicable | Unknown status | NBTXR3 activated by IMRT | NCT01946867 |