PROVECTUS BIOPHARMACEUTICALS, INC. (PVCT)
Provectus Biopharmaceuticals, Inc. is a clinical-stage biotechnology firm dedicated to pioneering immunotherapy treatments. These therapies are grounded in its proprietary halogenated xanthene platform. Among its key developments is PV-10, an experimental autolytic cancer immunotherapy. This treatment is being explored for a range of adult solid tumor malignancies, encompassing melanoma and various gastrointestinal cancers (such as hepatocellular carcinoma, metastatic colorectal cancer to the liver, metastatic neuroendocrine tumors to the liver, and metastatic uveal melanoma to the liver). It also targets pediatric solid tumors, including neuroblastoma, Ewing sarcoma, rhabdomyosarcoma, and osteosarcoma. Additionally, Provectus is advancing oral formulations of pharmaceutical-grade rose bengal sodium (cGMP RBS) to combat a broad spectrum of conditions. These include adult solid tumors (such as head and neck, breast, testicular, and colorectal cancers), pediatric blood cancers like leukemia, acute respiratory syndromes such as coronavirus, infections caused by multi-drug resistant bacteria (specifically Gram-negative bacteria), and certain ocular conditions, notably infectious keratitis. Furthermore, the company is progressing PH-10, an investigational immuno-dermatology agent designed to address inflammatory skin conditions like psoriasis and atopic dermatitis. Originally established in 2002, the company was initially named Provectus Pharmaceuticals, Inc., before rebranding as Provectus Biopharmaceuticals, Inc. in December 2013. Its operations are headquartered in Knoxville, Tennessee.
Sector: Pharmaceutical Preparations
Industry: Biotechnology
Provectus Biopharmaceuticals, Inc.
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based on 420.28M shares outstanding
Provectus Biopharmaceuticals, Inc. is a clinical-stage biotechnology firm dedicated to pioneering immunotherapy treatments. These therapies are grounded in its proprietary halogenated xanthene platform. Among its key developments is PV-10, an experimental autolytic cancer immunotherapy. This treatment is being explored for a range of adult solid tumor malignancies, encompassing melanoma and various gastrointestinal cancers (such as hepatocellular carcinoma, metastatic colorectal cancer to the liver, metastatic neuroendocrine tumors to the liver, and metastatic uveal melanoma to the liver).
It also targets pediatric solid tumors, including neuroblastoma, Ewing sarcoma, rhabdomyosarcoma, and osteosarcoma.
Additionally, Provectus is advancing oral formulations of pharmaceutical-grade rose bengal sodium (cGMP RBS) to combat a broad spectrum of conditions. These include adult solid tumors (such as head and neck, breast, testicular, and colorectal cancers), pediatric blood cancers like leukemia, acute respiratory syndromes such as coronavirus, infections caused by multi-drug resistant bacteria (specifically Gram-negative bacteria), and certain ocular conditions, notably infectious keratitis. Furthermore, the company is progressing PH-10, an investigational immuno-dermatology agent designed to address inflammatory skin conditions like psoriasis and atopic dermatitis. Originally established in 2002, the company was initially named Provectus Pharmaceuticals, Inc., before rebranding as Provectus Biopharmaceuticals, Inc. in December 2013.
Its operations are headquartered in Knoxville, Tennessee.
Leadership
Dominic Rodrigues
President & Executive Vice Chairman of the Board
Edward Pershing
Chief Executive Officer & Executive Chairman of Board
Eric Wachter
Co-Founder & Chief Technology Officer
Heather Raines
Chief Financial Officer
Employees
6
Country
US
Sector
Healthcare
Website
provectusbio.com
| Insider | Title | Type | Shares | Value | Date |
|---|---|---|---|---|---|
| CEO | Option Exercise | 7.6K | -- | Oct 23, 2026 | |
| CEO | Option Exercise | 0 | -- | Oct 23, 2026 | |
| CEO | Option Exercise | 22.6K | -- | Oct 10, 2026 | |
| CEO | Option Exercise | 0 | -- | Oct 10, 2026 | |
| CEO | Option Exercise | 0 | -- | Oct 3, 2026 | |
| CEO | Option Exercise | 13.2K | -- | Oct 3, 2026 |
| Name | Shares | % | Source |
|---|---|---|---|
Pershing Edward · may incl. warrants· filed Jul 2026 | 52.4M | 12.5% | 13D |
HOME FEDERAL BANK OF TENNESSEE | 100.0K | 0.0% | 13F |
Atlas Wealth LLC | 19.6K | 0.0% | 13F |
Financial Symmetry Inc | 10.2K | 0.0% | 13F |
HUNTINGTON NATIONAL BANK | 1 | 0.0% | 13F |
Insiders
Top institutional holders
based on 420.28M shares outstanding
30d Avg
66.56K
60d Avg
82.86K
90d Avg
108.96K