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PROVECTUS BIOPHARMACEUTICALS, INC. (PVCT)

Provectus Biopharmaceuticals, Inc. is a clinical-stage biotechnology firm dedicated to pioneering immunotherapy treatments. These therapies are grounded in its proprietary halogenated xanthene platform. Among its key developments is PV-10, an experimental autolytic cancer immunotherapy. This treatment is being explored for a range of adult solid tumor malignancies, encompassing melanoma and various gastrointestinal cancers (such as hepatocellular carcinoma, metastatic colorectal cancer to the liver, metastatic neuroendocrine tumors to the liver, and metastatic uveal melanoma to the liver). It also targets pediatric solid tumors, including neuroblastoma, Ewing sarcoma, rhabdomyosarcoma, and osteosarcoma. Additionally, Provectus is advancing oral formulations of pharmaceutical-grade rose bengal sodium (cGMP RBS) to combat a broad spectrum of conditions. These include adult solid tumors (such as head and neck, breast, testicular, and colorectal cancers), pediatric blood cancers like leukemia, acute respiratory syndromes such as coronavirus, infections caused by multi-drug resistant bacteria (specifically Gram-negative bacteria), and certain ocular conditions, notably infectious keratitis. Furthermore, the company is progressing PH-10, an investigational immuno-dermatology agent designed to address inflammatory skin conditions like psoriasis and atopic dermatitis. Originally established in 2002, the company was initially named Provectus Pharmaceuticals, Inc., before rebranding as Provectus Biopharmaceuticals, Inc. in December 2013. Its operations are headquartered in Knoxville, Tennessee.

Sector: Pharmaceutical Preparations

Industry: Biotechnology

Provectus Biopharmaceuticals, Inc. logo

Provectus Biopharmaceuticals, Inc.

OTC:PVCTHealthcare
+1.65%$0.0492
Mkt Cap$20.68M
Float239.82M
O/S420.28M
Inst Own0.0%
SI0.3%
Dilution
Provectus Biopharmaceuticals, Inc. logoOTC:PVCT$0.0492+1.65%
Historical Data
DateOpenHighLowCloseVolume
Key Metrics
Market Cap$20.68M
Enterprise Value--
P/E Ratio--
Est. Net Cash/Share--
Institutional Ownership0.03%

based on 420.28M shares outstanding

SectorHealthcare
IndustryBiotechnology
ExchangeOTC
CountryUSUS
IPO DateJan 15, 1997
Shares Outstanding420.28M
Float239.82M
Company Overview

Provectus Biopharmaceuticals, Inc. is a clinical-stage biotechnology firm dedicated to pioneering immunotherapy treatments. These therapies are grounded in its proprietary halogenated xanthene platform. Among its key developments is PV-10, an experimental autolytic cancer immunotherapy. This treatment is being explored for a range of adult solid tumor malignancies, encompassing melanoma and various gastrointestinal cancers (such as hepatocellular carcinoma, metastatic colorectal cancer to the liver, metastatic neuroendocrine tumors to the liver, and metastatic uveal melanoma to the liver).

It also targets pediatric solid tumors, including neuroblastoma, Ewing sarcoma, rhabdomyosarcoma, and osteosarcoma.

Additionally, Provectus is advancing oral formulations of pharmaceutical-grade rose bengal sodium (cGMP RBS) to combat a broad spectrum of conditions. These include adult solid tumors (such as head and neck, breast, testicular, and colorectal cancers), pediatric blood cancers like leukemia, acute respiratory syndromes such as coronavirus, infections caused by multi-drug resistant bacteria (specifically Gram-negative bacteria), and certain ocular conditions, notably infectious keratitis. Furthermore, the company is progressing PH-10, an investigational immuno-dermatology agent designed to address inflammatory skin conditions like psoriasis and atopic dermatitis. Originally established in 2002, the company was initially named Provectus Pharmaceuticals, Inc., before rebranding as Provectus Biopharmaceuticals, Inc. in December 2013.

Its operations are headquartered in Knoxville, Tennessee.

Leadership

Dominic Rodrigues

President & Executive Vice Chairman of the Board

Edward Pershing

Chief Executive Officer & Executive Chairman of Board

Eric Wachter

Co-Founder & Chief Technology Officer

Heather Raines

Chief Financial Officer

Employees

6

Country

US

Sector

Healthcare

Website

provectusbio.com

Analyst Coverage
No analyst coverage for this companyNo ratings, price targets, or covering firms on file.
Insider Trades
InsiderTypeShares
Pershing Edward profile photoPershing EdwardOption Exercise7.6K
Pershing Edward profile photoPershing EdwardOption Exercise0
Pershing Edward profile photoPershing EdwardOption Exercise22.6K
Pershing Edward profile photoPershing EdwardOption Exercise0
Pershing Edward profile photoPershing EdwardOption Exercise0
Pershing Edward profile photoPershing EdwardOption Exercise13.2K
Shareholders
0.0%
Institutional
(4)
0.0%
Insiderⓘ
(0)
12.5%
5%+ Owners
(1)
87.5%
Unattributed (incl. retail)ⓘ
Institutional0.0%
5%+ Beneficial12.5%
Unattributed (incl. retail)87.5%
Sources: 13F, 13D/13GO/S: 420.3M · as of 11 Aug 2026 · SEC cover page
Insiders & Institutional Holders
52-Week Range
$0.0380$0.0767
$0.0492(29th percentile)
Volume
Average Daily Volume66.08K
189.05K today vs 66.08K avg(+186%)

30d Avg

66.08K

60d Avg

82.61K

90d Avg

108.79K

Earnings
Dividend History
No dividend history available
Compliance Status
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