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Rallybio Corp (RLYB)

Rallybio Corporation is a clinical-stage biotechnology firm dedicated to discovering and bringing to market transformative therapies for individuals facing severe and uncommon illnesses. Its most advanced therapeutic candidate, RLYB212, is a monoclonal anti-HPA-1a antibody currently undergoing Phase II clinical trials. This candidate, along with RLYB211, is aimed at preventing fetal and neonatal alloimmune thrombocytopenia (FNAIT). The company's pipeline also includes RLYB114, a pegylated complement factor 5 (C5)-targeted Affibody molecule in preclinical development for addressing ophthalmic conditions driven by complement system activity. Furthermore, RLYB116, an inhibitor designed to target complement component 5 (C5) for various complement dysregulation disorders, has successfully completed its Phase 1 trial. Another preclinical antibody, RLYB332, is under investigation for treating severe anemia characterized by ineffective erythropoiesis and iron overload. Rallybio has established strategic collaborations to further its development efforts. It maintains an alliance with AbCellera for the identification, development, and commercialization of novel antibody-based therapeutics in rare diseases. Additionally, the firm partners with Exscientia on the creation of small molecule therapeutics for rare diseases, and with Johnson & Johnson to deliver therapeutic options to expectant mothers at risk of fetal and neonatal alloimmune thrombocytopenia. Established in 2018, Rallybio Corporation is headquartered in New Haven, Connecticut.

Sector: Pharmaceutical Preparations

Industry: Biotechnology

Rallybio Corporation logo

Rallybio Corporation

NASDAQ:RLYBHealthcare
+0.84%$15.54
AH$15.54+0.00%vs close
Mkt Cap$84.31M
Float4.41M
O/S5.43M
Vol
$ Vol
RVOL
Inst Own74.9%
SI0.9%
Earnings
Dilution
Pipeline3 lead-sponsored trials·0 active2 completed

Trials need funding. See this company's dilution risk and cash position.

Clinical Trials
Status
Phase
  • Phase 2
    Terminated

    Phase 2 Study on the Pharmacokinetics and Safety of RLYB212 in Pregnant Women at Higher Risk for HPA-1a Alloimmunization

    Anti-(integrin beta-3) human monoclonal antibody

    Fetal and Neonatal Alloimmune Thrombocytopenia

    Enrollment
    1
    Start
    Nov 2024
    Primary Completion
    Oct 2025
    Completion
    Oct 2025
    NCT06435845
  • Phase 1
    Completed

    Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of RLYB116 in Healthy Participants

    RLYB116 for Injection

    Hematologic Diseases, Autoimmune Diseases

    Enrollment
    16
    Start
    Apr 2025
    Primary Completion
    Feb 2026
    Completion
    Feb 2026
    NCT06797375
  • Observational
    Completed

    Study to Assess the Occurrence of HPA-1a Alloimmunization in Women With Higher Risk for Fetal and Neonatal Alloimmune Thrombocytopenia

    Clinical data collection

    Fetal and Neonatal Alloimmune Thrombocytopenia

    Enrollment
    14,390
    Start
    Mar 2022
    Primary Completion
    Jan 2025
    Completion
    Oct 2025
    NCT05345561