RECURSION PHARMACEUTICALS, INC. (RXRX)
Recursion Pharmaceuticals, Inc. operates as a biotechnology firm currently in its clinical development phase. The company's mission is to revolutionize drug discovery by decoding biological processes, utilizing an integrated approach that combines technological innovations across biology, chemistry, automation, data science, and engineering. Their developmental pipeline features several clinical-stage compounds: REC-994, which is advancing through Phase IIa trials for cerebral cavernous malformation; REC-3599, currently in Phase I trials for GM2 gangliosidosis; REC-2282, aimed at treating neurofibromatosis type 2; and REC-4881, intended for familial adenomatous polyposis. Beyond these, Recursion maintains a comprehensive preclinical portfolio. This includes REC-3964 for Clostridium difficile colitis, REC-64917 targeting neural or systemic inflammation, and REC-65029 for HRD-negative ovarian cancer. Further preclinical candidates are REC-648918, designed to enhance anti-tumor immunity; REC-2029 for wnt-mutant hepatocellular carcinoma; REC-14221 for various solid and hematological malignancies; and REC-64151, focused on addressing immune checkpoint resistance in KRAS/STK11 mutant non-small cell lung cancer. The company has established strategic collaborations and agreements with partners such as Bayer AG, the University of Utah Research Foundation, the Ohio State Innovation Foundation, Chromaderm, Inc., and Takeda Pharmaceutical Company Limited. Recursion Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Salt Lake City, Utah.
Sector: Biological Products, (No Diagnostic Substances)
Industry: Biotechnology
Recursion Pharmaceuticals, Inc.
Trials need funding. See this company's dilution risk and cash position.
- Phase 2/3Terminated
Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated Meningiomas
REC-2282, Placebo
Neurofibromatosis Type 2
NCT05130866Enrollment25StartJun 2022Primary CompletionAug 2025CompletionAug 2025 - Phase 2Completed
The Symptomatic Cerebral Cavernous Malformation Trial of REC-994
REC-994, Placebo
Cerebral Cavernous Malformation
NCT05085561Enrollment62StartMar 2022Primary CompletionJun 2025CompletionJun 2025 - Phase 2Terminated
A Study of REC-4881 in Participants With Cancers Which Have an AXIN1 or APC Mutation
REC-4881
AXIN1 Gene Mutation, APC Gene Mutation +1
NCT06005974Enrollment18StartJan 2024Primary CompletionFeb 2025CompletionFeb 2025 - Phase 2Terminated
The Clostridioides Difficile Trial of REC-3964
REC-3964
Recurrent Clostridioides Difficile Infection
NCT06536465Enrollment3StartOct 2024Primary CompletionMay 2025CompletionMay 2025 - Phase 1/2Recruiting
Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)
REC-4881, Placebo
Familial Adenomatous Polyposis
NCT05552755Enrollment67StartJul 2023Primary CompletionJun 2027est.CompletionSep 2027est. - Phase 1/2Recruiting
Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors
GTAEXS617, SoC
Head and Neck Squamous Cell Carcinoma (HNSCC), Pancreatic Adenocarcinoma +4
NCT05985655Enrollment230StartJul 2023Primary CompletionJan 2028est.CompletionMay 2028est. - Phase 1/2Recruiting
A Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer
REC-1245
Unresectable, Locally Advanced +2
NCT06678659Enrollment170StartNov 2024Primary CompletionOct 2028est.CompletionOct 2028est. - Phase 1/2Recruiting
REC-7735 in Participants With Solid Tumors
REC-7735
Solid Tumors
NCT07819136Enrollment90StartSep 2026est.Primary CompletionJan 2031est.CompletionJan 2031est. - Phase 1Recruiting
Dose Determining Study of EXS73565 in Participants With Relapsed or Refractory B-Cell Malignancies
EXS73565
Relapsed or Refractory B-cell Malignancies, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) +5
NCT06980116Enrollment85StartMar 2025Primary CompletionJun 2028est.CompletionDec 2028est. - Phase 1Recruiting
Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors
EXS74539
Solid Tumor, Small Cell Lung Cancer (SCLC) +10
NCT07517198Enrollment40StartApr 2026Primary CompletionMar 2029est.CompletionMar 2029est.
| Drug / Therapy | Link | ||
|---|---|---|---|
| Phase 2/3 | Terminated | REC-2282, Placebo | NCT05130866 |
| Phase 2 | Completed | REC-994, Placebo | NCT05085561 |
| Phase 2 | Terminated | REC-4881 | NCT06005974 |
| Phase 2 | Terminated | REC-3964 | NCT06536465 |
| Phase 1/2 | Recruiting | REC-4881, Placebo | NCT05552755 |
| Phase 1/2 | Recruiting | GTAEXS617, SoC | NCT05985655 |
| Phase 1/2 | Recruiting | REC-1245 | NCT06678659 |
| Phase 1/2 | Recruiting | REC-7735 | NCT07819136 |
| Phase 1 | Recruiting | EXS73565 | NCT06980116 |
| Phase 1 | Recruiting | EXS74539 | NCT07517198 |