SAVA (SAVA)
Cassava Sciences, Inc.
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Cassava Sciences, Inc. is a biopharmaceutical enterprise in the clinical development phase, specializing in the creation of treatments for neurodegenerative disorders.
The company's primary experimental drug, simufilam, a small-molecule compound, has successfully concluded its Phase 2b clinical trials. In parallel, they are advancing SavaDx, an investigational blood-based biomarker test designed to aid in the detection of Alzheimer's disease. Established in 1998 and headquartered in Austin, Texas, the company underwent a name change in March 2019, previously operating as Pain Therapeutics, Inc.
Leadership
Claude Nicaise, M.D.
Chairman of the Board of Directors
Eric J. Schoen
Chief Financial Officer
Freda Nassif
Chief Business Officer & Chief Commercial Officer
James W. Kupiec, M.D.
Chief Medical Officer
Employees
30
Country
US
Sector
Healthcare
Website
cassavasciences.com
| Insider | Title | Type | Shares | Value | Date |
|---|---|---|---|---|---|
| Director | Purchase | 8.6K | $24.9K | Nov 24, 2025 | |
| President & CEO | Purchase | 150.0K | $414.0K | Nov 20, 2025 | |
| President & CEO | Purchase | 73.4K | $201.8K | Nov 19, 2025 | |
| Director | Grant/Award | 53.0K | -- | Oct 21, 2025 | |
| SVP & General Counsel | Purchase | 13.7K | $39.9K | Sep 30, 2025 | |
| President & CEO | Purchase | 7.2K | $16.4K | Sep 22, 2025 |
| Name | Shares | % | Source |
|---|---|---|---|
Nachtrab Matthew · may incl. warrants· filed Nov 2024 | 2.3M | 4.7% | 13G |
The Vanguard Group · filed Jul 2025 | 2.2M | 4.5% | 13G |
Remi Barbier · may incl. warrants· filed Nov 2024 | 2.1M | 4.2% | 13G |
VANGUARD CAPITAL MANAGEMENT LLC | 2.0M | -- | 13F |
TWO SIGMA INVESTMENTS, LP | 1.7M | -- | 13F |
MARSHALL WACE, LLP | 1.6M | -- | 13F |
BlackRock, Inc. · also on 13F· may incl. warrants· filed Jul 2025 | 1.5M | 3.2% | 13G |
BlackRock, Inc. | 1.5M | -- | 13F |
GOLDMAN SACHS GROUP INC | 668.8K | -- | 13F |
GEODE CAPITAL MANAGEMENT, LLC | 615.5K | -- | 13F |
Insiders
- Anderson Robert Eugene JrDirector
- Barry RichardPresident & CEO
- Bir Dawn CarterDirector
- Cook Robert ChristopherSVP & General Counsel
- SCANNON PATRICK J MD PHDDirector
- O DONNELL MICHAEL JDirector
- Nicaise ClaudeDirector
- GUSSIN ROBERT ZDirector
- Gravier PierreDirector
- Schoen EricChief Financial Officer
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