Stoke Therapeutics, Inc. (STOK)
Stoke Therapeutics, Inc. is an emerging biopharmaceutical company dedicated to developing innovative antisense oligonucleotide (ASO) therapies. Its primary focus is to target and address the fundamental causes of severe genetic disorders, particularly within the United States. The company employs its exclusive Targeted Augmentation of Nuclear Gene Output (TANGO) platform to engineer ASOs that precisely enhance protein expression. Stoke's most advanced candidate, STK-001, is currently progressing through Phase I/IIa clinical trials for Dravet syndrome, a severe and debilitating genetic epilepsy. Additionally, STK-002 is in the preclinical development stage for treating autosomal dominant optic atrophy. The company has also established a licensing and collaborative agreement with Acadia Pharmaceuticals Inc. to identify, develop, and market new RNA-based medicines for critical and rare genetic neurodevelopmental conditions impacting the central nervous system. Formerly known as ASOthera Pharmaceuticals, Inc., the company rebranded to Stoke Therapeutics, Inc. in May 2016. Founded in 2014, Stoke Therapeutics, Inc. maintains its headquarters in Bedford, Massachusetts.
Sector: Pharmaceutical Preparations
Industry: Biotechnology
Stoke Therapeutics, Inc.
NASDAQ:STOKHealthcare · Biotechnology
-0.23%$26.29
AH$27.00+2.70%vs close
Mkt Cap$1.7B
Float54.4M
O/S64.53M
Vol
$ Vol
RVOL
Inst Own-
SI18.9%
Earnings
Dilution
Financials Summary
Revenue$184.42M
Net Income-$6.88M
Total Assets$418.43M
Free Cash Flow$44.91M
Debt & Equity
Debt 1%
Equity 99%
Total Debt$3.01M
Total Equity$352.46M
Shares Outstanding
Short Interest
Split History
No splits on record
Nothing in STOK's public trading history: no forward or reverse split has affected the share count.
Balance Sheet Details
Assets$418.43M
Liabilities$65.98M
Accounts Receivable$7.91M
Accounts Payable$4.94M
Inventory$0
PP&E (Net)$6.25M
Goodwill$0
Intangible Assets$0
Income Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 |
| Revenue | $184.42M | $36.55M | $8.78M | $12.4M | $0 | $0 | $0 | $0 | $0 |
| YoY Growth | 404.5% | 316.3% | -29.2% | - | - | - | - | - | - |
| Cost of Revenue | $0 | $0 | $0 | $0 | $0 | $1.93M | $450K | $214K | $113K |
| Gross Profit | $184.42M | $36.55M | $8.78M | $12.4M | $0 | -$1.93M | -$450K | -$214K | -$113K |
| Gross Margin | 100.0% | 100.0% | 100.0% | 100.0% | - | - | - | - | - |
| Research and Development | $137.92M | $89.13M | $82.23M | $77.84M | $54.17M | $32.2M | $23.31M | $8.37M | $3.6M |
| Selling, General, and Administrative | $67.09M | $48.79M | $41.32M | $38.92M | $31.9M | $20.85M | $11.91M | $4.41M | $1.96M |
| Other | $0 | $0 | $0 | $0 | $0 | -$1.93M | $0 | -$10K | -$4K |
| Total Operating Expenses | $205.01M | $137.93M | $123.55M | $116.76M | $86.06M | $51.12M | $35.23M | $12.78M | $5.55M |
| Operating Income (EBIT) | -$20.59M | -$101.37M | -$114.77M | -$104.36M | -$86.06M | -$53.04M | -$35.68M | -$12.78M | -$5.55M |
| Operating Margin | -11.2% | -277.3% | -1307.2% | -841.2% | - | - | - | - | - |
| Interest Expense | $9K | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Interest Income | $13.77M | $12.64M | $9.91M | $3.12M | $120K | $744K | $3.35M | $270K | $0 |
| Other Income (Expense) | $13.71M | $12.39M | $10.07M | $3.29M | $260K | $801K | $3.35M | $260K | -$4K |
| Income Before Tax (EBT) | -$6.88M | -$88.98M | -$104.7M | -$101.07M | -$85.81M | -$52.24M | -$32.33M | -$12.52M | -$5.56M |
| Income Tax Expense | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Net Income | -$6.88M | -$88.98M | -$104.7M | -$101.07M | -$85.81M | -$52.24M | -$32.33M | -$12.52M | -$5.56M |
| Net Income Margin | -3.7% | -243.4% | -1192.5% | -814.7% | - | - | - | - | - |
| Supplementary Data | |||||||||
| EPS | -0.12 | -1.65 | -2.38 | -2.60 | -2.34 | -1.56 | -1.59 | -0.53 | -0.24 |
| Diluted EPS | -0.12 | -1.65 | -2.38 | -2.60 | -2.34 | -1.56 | -1.59 | -0.53 | -0.24 |
| Weighted Average OS | 59.22M | 54.01M | 43.99M | 38.90M | 36.74M | 33.49M | 17.97M | 23.51M | 23.51M |
| EBITDA | -$5.12M | -$86.8M | -$102.23M | -$99.52M | -$84.83M | -$51.35M | -$31.88M | -$12.57M | -$5.44M |
| EBITDA Margin | -2.8% | -237.5% | -1164.4% | -802.3% | - | - | - | - | - |
Balance Sheet
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 |
| Assets | |||||||||
| Current Assets | |||||||||
| Cash and Cash Equivalents | $84.22M | $127.98M | $191.44M | $113.56M | $144.9M | $287.31M | $222.47M | $105.4M | $1.8M |
| Short-Term Investments | $200.45M | $88.92M | $9.95M | $116.04M | $74.92M | $0 | $0 | $0 | $0 |
| Cash and Short-Term Investments | $284.67M | $216.9M | $201.39M | $229.59M | $219.81M | $287.31M | $222.47M | $105.4M | $1.8M |
| Accounts Receivable | $7.91M | $700K | $64K | $588K | $132K | $6K | $281K | $196K | $0 |
| Inventory | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Current Assets | $4.39M | $4.04M | $2.56M | $2.96M | $2.33M | $181K | $0 | $0 | $0 |
| Total Current Assets | $305.7M | $232.76M | $215.34M | $244.07M | $229.22M | $293.93M | $226.03M | $106.14M | $1.91M |
| Long-Term Assets | |||||||||
| Property, Plant & Equipment Net | $6.25M | $8.25M | $12.43M | $11.43M | $9.08M | $3.79M | $2.51M | $1.19M | $473K |
| Goodwill | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Intangible Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Long-Term Investments | $0 | $29.82M | $0 | $0 | $0 | $0 | $0 | $204K | $56K |
| Deferred Tax Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Long-Term Assets | $106.49M | $721K | $569K | $569K | $569K | $205K | $205K | $0 | $0 |
| Total Long-Term Assets | $112.73M | $38.8M | $13M | $12M | $9.65M | $4M | $2.72M | $1.4M | $529K |
| Other Assets | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Assets | $418.43M | $271.56M | $228.34M | $256.07M | $238.87M | $297.93M | $228.75M | $107.54M | $2.44M |
| Liabilities | |||||||||
| Current Liabilities | |||||||||
| Accounts Payable | $4.94M | $2.5M | $1.7M | $766K | $2.38M | $1.5M | $751K | $1.07M | $141K |
| Short-Term Debt | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $3M |
| Current Income Tax Payable | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Current Unearned Revenue | $11.9M | $18.99M | $15.31M | $14.88M | $0 | $0 | $0 | $0 | -$3M |
| Other Current Liabilities | $15.04M | $8.44M | $6.47M | $6.26M | $5.92M | $4.58M | $2.11M | $0 | $0 |
| Total Current Liabilities | $57.88M | $40.06M | $30.82M | $31.39M | $17.14M | $11.43M | $4.1M | $2.47M | $3.71M |
| Long-Term Liabilities | |||||||||
| Long-Term Debt | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Long-Term Unearned Revenue | $6.96M | $0 | $33.07M | $36.86M | $0 | $0 | $0 | $0 | $0 |
| Long-Term Deferred Tax Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Long-Term Liabilities | $1.14M | $26K | $4.88M | $2.97M | $417K | $422K | $221K | $4K | $16K |
| Total Long-Term Liabilities | $8.1M | $2.48M | $37.96M | $39.82M | $3.95M | $422K | $221K | $4K | $16K |
| Other Liabilities | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities | $65.98M | $42.53M | $68.78M | $71.22M | $21.09M | $11.85M | $4.32M | $2.47M | $3.73M |
| Stockholders' Equity | |||||||||
| Preferred Stock | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $2K | $5K |
| Common Stock | $5K | $5K | $5K | $4K | $4K | $4K | $3K | $1K | $1K |
| Retained Earnings | -$497.71M | -$490.83M | -$401.85M | -$297.15M | -$196.08M | -$110.28M | -$58.03M | -$25.71M | -$13.19M |
| Comprehensive Income & Other | $543K | -$151K | -$24K | -$1.18M | -$168K | $0 | $0 | -$379K | -$172K |
| Other Stockholders' Equity | $850.17M | $719.85M | $561.41M | $482M | $413.86M | $396.35M | $282.46M | $130.78M | $11.9M |
| Total Equity | $352.46M | $229.02M | $159.56M | $184.85M | $217.78M | $286.08M | $224.43M | $105.07M | -$1.29M |
| Minority Interest | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities and Equity | $418.43M | $271.56M | $228.34M | $256.07M | $238.87M | $297.93M | $228.75M | $107.54M | $2.44M |
| Supplementary Data | |||||||||
| Total Debt | $3.01M | $4.77M | $2.06M | $2.36M | $5.04M | $1.07M | $0 | $0 | $3M |
| Net Debt | -$81.21M | -$123.21M | -$189.38M | -$111.2M | -$139.86M | -$286.24M | -$222.47M | -$105.4M | $1.2M |
Cash Flow Statement
| Period | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|
| Currency | USD | USD | USD | USD | USD | USD | USD | USD | USD |
| Period Ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 |
| Operating Activities | |||||||||
| Net Income | -$6.88M | -$88.98M | -$104.7M | -$101.07M | -$85.81M | -$52.24M | -$32.33M | -$12.52M | -$5.56M |
| Depreciation & Amortization | $1.77M | $2.18M | $2.47M | $1.55M | $974K | $888K | $450K | $214K | $113K |
| Deferred Income Tax | $0 | $0 | $0 | $0 | $172K | $3K | $0 | $0 | $0 |
| Stock-Based Compensation | $32.24M | $27.47M | $25.26M | $22.85M | $16.45M | $5.77M | $1.92M | $240K | $26K |
| Changes in Working Capital: | |||||||||
| Accounts Receivable | -$4.27M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Inventory | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Accounts Payable | $21.29M | $3.09M | -$3.21M | $121K | $2.9M | $5.2M | $891K | $1.74M | $100K |
| Other Working Capital | -$675K | -$31.23M | -$2.82M | $42.9M | -$2.85M | -$2.88M | -$2M | $1.09M | $31K |
| Total Working Capital Change | $16.35M | -$28.14M | -$6.03M | $43.02M | $46K | $2.33M | -$1.1M | $1.09M | $31K |
| Other Non-Cash Items | $2.12M | $623K | $1.94M | $1.78M | $1.26M | $1.04M | $3K | $10K | $4K |
| Net Cash from Operating | $45.59M | -$86.85M | -$81.07M | -$31.87M | -$66.91M | -$42.22M | -$31.05M | -$10.96M | -$5.38M |
| Investing Activities | |||||||||
| Capital Expenditures | -$670K | -$203K | -$1.62M | -$3.96M | -$1.2M | -$1.05M | -$1.64M | -$935K | -$113K |
| Acquisitions | $0 | $0 | $0 | $45.34M | $75.23M | $0 | $1K | $10K | $0 |
| Purchases of Investments | -$322.72M | -$167.27M | $0 | -$201.32M | -$87.23M | $0 | $0 | $0 | $0 |
| Sales of Investments | $136.58M | $60M | $107.56M | $159.4M | $12M | $0 | $0 | $0 | $0 |
| Other Investing Activities | $0 | $0 | $0 | -$45.34M | -$75.23M | $0 | $0 | $10K | $0 |
| Net Cash from Investing | -$186.81M | -$107.47M | $105.95M | -$45.88M | -$76.43M | -$1.05M | -$1.63M | -$925K | -$113K |
| Financing Activities | |||||||||
| Debt Repaid | - | - | - | - | - | - | - | - | - |
| Common Stock Issuance | $97.39M | $128.84M | $52.08M | $45.34M | $1.29M | $105.4M | $151.91M | $115.64M | $2.98M |
| Common Stock Repurchases | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Dividends Paid | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Other Financing Activities | $0 | $2.25M | $926K | $1.06M | -$2K | $2.71M | -$2.15M | -$361K | $2.97M |
| Net Cash from Financing | $97.39M | $131.09M | $53.01M | $46.41M | $1.28M | $108.11M | $149.76M | $115.64M | $5.97M |
| Forex Effect | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | -$43.84M | -$63.23M | $77.89M | -$31.34M | -$142.05M | $64.84M | $117.07M | $103.75M | $477K |
| Supplementary Data | |||||||||
| Operating Cash Flow | $45.59M | -$86.85M | -$81.07M | -$31.87M | -$66.91M | -$42.22M | -$31.05M | -$10.96M | -$5.38M |
| Capital Expenditure | -$670K | -$203K | -$1.62M | -$3.96M | -$1.2M | -$1.05M | -$1.64M | -$935K | -$113K |
| Free Cash Flow | $44.91M | -$87.05M | -$82.68M | -$35.83M | -$68.11M | -$43.27M | -$32.69M | -$11.9M | -$5.5M |
| Cash at Beginning | $128.78M | $192.01M | $114.13M | $145.46M | $287.51M | $222.68M | $105.6M | $1.85M | $1.38M |
| Cash at End | $84.94M | $128.78M | $192.01M | $114.13M | $145.46M | $287.51M | $222.68M | $105.6M | $1.85M |