Skip to main content
Signal8
Launch Terminal

TransMedics Group, Inc. (TMDX)

TransMedics Group, Inc. operates as a commercial-stage medical technology enterprise, committed to transforming the landscape of organ transplant therapy for patients worldwide grappling with end-stage organ failure. At the core of their offerings is the Organ Care System (OCS), an innovative, portable solution engineered to perfuse, optimize, and continuously monitor donor organs. This system leverages exclusive, tailored technology to meticulously recreate near-physiological conditions for these vital organs while they remain outside the human body. The OCS suite encompasses specialized modules: OCS LUNG, which facilitates the preservation of standard criteria donor lungs for double-lung transplants; OCS Heart, designed for the extracorporeal perfusion and maintenance of donor hearts; and OCS Liver, dedicated to the preservation of donor livers. Founded in 1998, TransMedics is headquartered in Andover, Massachusetts.

Sector: Electromedical & Electrotherapeutic Apparatus

Industry: Medical - Devices

TransMedics Group, Inc. logo

TransMedics Group, Inc.

NASDAQ:TMDXHealthcare
-1.68%$65.99
AH$65.85-0.21%vs close
Mkt Cap$2.29B
Float32.16M
O/S34.68M
Vol
$ Vol
RVOL
Inst Own100.9%
SI27.3%
Earnings
Dilution
TransMedics Group, Inc. logoNASDAQ:TMDX$65.99-1.68%
Phase Distribution
26 lead-sponsored trials·9 active·14 completed
Not applicable26
Status Overview
Not yet recruiting1
Recruiting4
Active, not recruiting5
Completed14
Stopped2

Trials need funding. See this company's dilution risk and cash position.

Clinical Trials
Status
  • Not applicable
    Completed

    Randomized Study of Organ Care System Cardiac for Preservation of Donated Hearts for Eventual Transplantation

    Organ Care System, Cold Cardioplegia Solution

    Heart Failure

    Enrollment
    128
    Start
    Mar 2009
    Primary Completion
    Oct 2013
    Completion
    Nov 2013
    NCT00855712
  • Not applicable
    Completed

    International Randomized Study of the TransMedics Organ Care System (OCS Lung) for Lung Preservation and Transplantation

    OCS Lung, Cold flush and storage

    Lung Preservation

    Enrollment
    320
    Start
    Nov 2011
    Primary Completion
    Sep 2014
    Completion
    Apr 2016
    NCT01630434
  • Not applicable
    Completed

    International EXPAND Lung Pivotal Trial

    OCS Lung Preservation

    Lung Transplant

    Enrollment
    79
    Start
    Nov 2013
    Primary Completion
    Nov 2016
    Completion
    Apr 2018
    NCT01963780
  • Not applicable
    Completed

    International EXPAND Heart Pivotal Trial

    Preservation of Hearts for Transplantation

    Heart Transplant

    Enrollment
    75
    Start
    Sep 2015
    Primary Completion
    Apr 2018
    Completion
    Mar 2019
    NCT02323321
  • Not applicable
    Completed

    Trial of the TransMedics Organ Care System™ Liver For Preserving and Assessing Donor Livers for Transplantation

    OCS Liver

    Liver Preservation

    Enrollment
    25
    Start
    May 2016
    Primary Completion
    Sep 2017
    Completion
    Jan 2018
    NCT02449694
  • Not applicable
    Completed

    OCS Liver PROTECT Trial: Preserving and Assessing Donor Livers for Transplantation

    OCS™ Liver System, Control

    Liver Transplantation, Liver Preservation for Transplant

    Enrollment
    300
    Start
    Jan 2016
    Primary Completion
    Oct 2019
    Completion
    Nov 2021
    NCT02522871
  • Not applicable
    Terminated

    OCS Lung System EXPAND II Trial

    OCS Lung Preservation

    Lung Transplantation

    Enrollment
    46
    Start
    Mar 2018
    Primary Completion
    Aug 2019
    Completion
    Jul 2022
    NCT03343535
  • Observational
    Active, not recruiting

    OCS™ Lung TOP Registry For Donor Lungs for Transplantation

    OCS Lung System

    Lung Transplantation

    Enrollment
    458
    Start
    Dec 2018
    Primary Completion
    Nov 2025est.
    Completion
    Nov 2029est.
    NCT03639025
  • Not applicable
    Completed

    Donors After Circulatory Death Heart Trial

    OCS Heart System, Cold Storage

    Heart Transplant

    Enrollment
    180
    Start
    Nov 2019
    Primary Completion
    Apr 2021
    Completion
    Sep 2021
    NCT03831048
  • Not applicable
    Completed

    Heart EXPAND Continued Access Protocol

    OCS Heart System

    Heart Transplant

    Enrollment
    75
    Start
    Apr 2019
    Primary Completion
    Sep 2021
    Completion
    Aug 2022
    NCT03835754
  • Observational
    Completed

    INSPIRE Continuation Post-Approval Study

    OCS Lung System

    Bronchiolitis Obliterans

    Enrollment
    220
    Start
    Jun 2019
    Primary Completion
    Oct 2021
    Completion
    Oct 2021
    NCT03868904
  • Not applicable
    Completed

    OCS Liver PROTECT Continued Access Protocol

    OCS Liver System

    Liver Transplant

    Enrollment
    74
    Start
    Feb 2020
    Primary Completion
    Feb 2021
    Completion
    Feb 2023
    NCT04186221
  • Observational
    Completed

    OCS Lung Expand Post-Approval Study - Expand Follow-Up Data Collection

    OCS Lung System

    OCS Lung System

    Enrollment
    79
    Start
    Dec 2018
    Primary Completion
    Sep 2021
    Completion
    Sep 2021
    NCT04194398
  • Not applicable
    Terminated

    OCS Liver DCD Trial

    OCS Liver System

    Liver Transplant

    Enrollment
    9
    Start
    Jul 2020
    Primary Completion
    Mar 2022
    Completion
    Dec 2024
    NCT04194437
  • Not applicable
    Completed

    Donor After Circulatory Death Heart CAP Trial

    Transplant

    Heart Transplant

    Enrollment
    90
    Start
    Nov 2020
    Primary Completion
    Dec 2021
    Completion
    Jun 2022
    NCT04615182
  • Observational
    Active, not recruiting

    OCS Heart Perfusion Post-Approval Registry

    OCS Heart System

    Transplant

    Enrollment
    350
    Start
    Sep 2021
    Primary Completion
    Dec 2025est.
    Completion
    Dec 2029est.
    NCT05047068
  • Observational
    Active, not recruiting

    OCS Liver Perfusion (OLP) Post-Approval Registry

    OCS Liver

    Liver Transplant

    Enrollment
    166
    Start
    Oct 2021
    Primary Completion
    Mar 2024
    Completion
    Jun 2026est.
    NCT05074160
  • Observational
    Active, not recruiting

    OCS Heart EXPAND + CAP Continued Follow-Up

    OCS Heart

    Heart Transplant

    Enrollment
    150
    Start
    Sep 2015
    Primary Completion
    Aug 2026est.
    Completion
    Aug 2026est.
    NCT05096299
  • Observational
    Completed

    OCS Liver PROTECT Continuation Post-Approval Study

    OCS Liver

    Liver Transplant

    Enrollment
    300
    Start
    Jan 2016
    Primary Completion
    Nov 2021
    Completion
    Nov 2021
    NCT05096741
  • Observational
    Completed

    OCS Liver PROTECT Continued Access Protocol (CAP) Continuation Post-Approval Study

    OCS Liver

    Liver Transplant

    Enrollment
    74
    Start
    Feb 2020
    Primary Completion
    Feb 2023
    Completion
    Feb 2023
    NCT05096754
  • Observational
    Active, not recruiting

    OCS DCD Heart + CAP Continued Follow-Up

    OCS Heart

    Heart Transplant

    Enrollment
    276
    Start
    Nov 2019
    Primary Completion
    Oct 2026est.
    Completion
    Oct 2026est.
    NCT05741723
  • Observational
    Recruiting

    US National OCS Heart Perfusion (OHP) Registry

    OCS Heart

    Heart Transplant

    Enrollment
    100,000
    Start
    Aug 2023
    Primary Completion
    Aug 2029est.
    Completion
    Aug 2033est.
    NCT05915299
  • Observational
    Recruiting

    US National OCS Liver Perfusion (OLP) Registry

    OCS Liver

    Liver Transplant

    Enrollment
    100,000
    Start
    Oct 2021
    Primary Completion
    Oct 2031est.
    Completion
    Oct 2031est.
    NCT05940857
  • Observational
    Recruiting

    US National TOP Registry

    OCS Lung

    Lung Transplant

    Enrollment
    10,000
    Start
    Jan 2025
    Primary Completion
    Nov 2034est.
    Completion
    Nov 2039est.
    NCT06513091
  • Not applicable
    Recruiting

    Enhancing Heart Allograft Function With the OCS Heart System Trial

    OCS Heart, Static Cold Storage (SCS)

    Heart Transplant

    Enrollment
    655
    Start
    Jan 2026est.
    Primary Completion
    Jan 2027est.
    Completion
    Jul 2027est.
    NCT07145515

1-25 of 26

Search ClinicalTrials.gov for “TransMedics Group”