Taysha Gene Therapies, Inc. (TSHA)
Taysha Gene Therapies, Inc. is a biotech firm specializing in the creation and market introduction of gene therapies that utilize adeno-associated virus (AAV) vectors. Its core mission is to tackle inherited diseases affecting the central nervous system (CNS). The company's development pipeline features several key programs: TSHA-120 is aimed at giant axonal neuropathy; TSHA-102 is in development for Rett syndrome; TSHA-121 and TSHA-118 are both being advanced for CLN1 disease; TSHA-105 addresses SLC13A5 Deficiency; and TSHA-101 targets GM2 gangliosidosis. Furthermore, Taysha has forged a strategic alliance with The University of Texas Southwestern Medical Center to jointly advance and bring to market innovative gene therapy solutions. Founded in 2019, the company operates from its headquarters in Dallas, Texas.
Sector: Biological Products, (No Diagnostic Substances)
Industry: Biotechnology
Taysha Gene Therapies, Inc.
Trials need funding. See this company's dilution risk and cash position.
- Phase 3Active, not recruiting
A Phase 1/2/3 Study of TSHA-102 Gene Therapy in Females With Rett Syndrome (REVEAL Pivotal Study)
TSHA-102
Rett Syndrome
NCT05606614Enrollment17StartMar 2023Primary CompletionJun 2031est.CompletionJun 2031est. - Phase 3Active, not recruiting
Safety and Preliminary Efficacy of TSHA-102 Gene Therapy in Pediatric Females Aged >2 to <4 Years With Rett Syndrome
TSHA-102
Rett Syndrome
NCT07480564Enrollment4StartMay 2026Primary CompletionJun 2031est.CompletionJun 2031est. - Phase 1/2Active, not recruiting
Safety and Efficacy of TSHA-102 in Pediatric Females With Rett Syndrome (REVEAL Pediatric Study)
TSHA-102
Rett Syndrome
NCT06152237Enrollment6StartDec 2023Primary CompletionNov 2028est.CompletionNov 2031est. - ObservationalWithdrawn
A Study of the Natural Course of SURF1 Deficiency
None (Observational study)
Leigh Syndrome
NCT05277363Enrollment0StartMay 2022Primary CompletionMay 2022CompletionMay 2022
| Drug / Therapy | Link | ||
|---|---|---|---|
| Phase 3 | Active, not recruiting | TSHA-102 | NCT05606614 |
| Phase 3 | Active, not recruiting | TSHA-102 | NCT07480564 |
| Phase 1/2 | Active, not recruiting | TSHA-102 | NCT06152237 |
| Observational | Withdrawn | None (Observational study) | NCT05277363 |