Viking Therapeutics, Inc. (VKTX)
Viking Therapeutics, Inc. operates as a clinical-stage biopharmaceutical company, specializing in the creation of novel treatments for metabolic and endocrine conditions. The company's leading investigational drug, VK2809, is an orally administered, tissue and receptor-selective agonist of the thyroid hormone receptor beta (TRß). This compound is currently progressing through Phase IIb clinical trials, targeting both non-alcoholic steatohepatitis (NASH) in biopsy-confirmed patients and non-alcoholic fatty liver disease (NAFLD). Viking's pipeline also features VK5211, an oral, non-steroidal selective androgen receptor modulator undergoing Phase II studies for individuals recuperating from non-elective hip fracture surgery. Additionally, VK0612, an oral drug candidate for type 2 diabetes, is poised to enter Phase IIb trials. The firm is also developing VK0214, another orally active, tissue and receptor-selective TRß agonist, specifically aimed at X-linked adrenoleukodystrophy. Founded in 2012, Viking Therapeutics is headquartered in San Diego, California.
Sector: Pharmaceutical Preparations
Industry: Biotechnology
Viking Therapeutics, Inc.
Trials need funding. See this company's dilution risk and cash position.
- Phase 3Active, not recruiting
VK2735 for Weight Management Type 2 Diabetes Phase 3 (VANQUISH 2)
VK2735
Weight Loss
NCT07104383Enrollment1,100StartJun 2025Primary CompletionJul 2027est.CompletionAug 2027est. - Phase 3Active, not recruiting
VK2735 for Weight Management Phase 3
VK2735
Weight Loss
NCT07104500Enrollment4,500StartJun 2025Primary CompletionJul 2027est.CompletionAug 2027est. - Phase 3Not yet recruiting
Oral VK2735 for Weight Management Phase 3 (SUNRISE 1)
VK2735, Placebo comparator
Weight Loss
NCT07868835Enrollment560StartNov 2026est.Primary CompletionJul 2028est.CompletionAug 2028est. - Phase 3Not yet recruiting
Oral VK2735 for Weight Management in Adults With Type 2 Diabetes Mellitus Phase 3 (SUNRISE 2)
VK2735 Oral, Placebo Comparator
Weight Loss
NCT07868939Enrollment560StartNov 2026est.Primary CompletionOct 2028est.CompletionDec 2028est. - Phase 2Completed
Acute Hip Fracture Study in Patients 65 Years or Greater
VK5211, Placebo
Hip Fractures
NCT02578095Enrollment108StartOct 2015Primary CompletionNov 2017CompletionDec 2017 - Phase 2Completed
Safety and Tolerability of VK2809 in Patients With Primary Hypercholesterolemia and Non-Alcoholic Fatty Liver Disease
VK2809, Placebo
Hyperlipidemia, NAFLD
NCT02927184Enrollment59StartSep 2016Primary CompletionMar 2019CompletionMar 2019 - Phase 2Completed
A Study to Assess the Efficacy and Safety of VK2809 for 52 Weeks in Subjects With Biopsy Proven NASH
VK2809, Placebos
NASH - Nonalcoholic Steatohepatitis
NCT04173065Enrollment248StartNov 2019Primary CompletionMay 2023CompletionJan 2024 - Phase 2Completed
VK2735 for Weight Management Phase 2
VK2735, Placebo
Weight Loss
NCT06068946Enrollment176StartAug 2023Primary CompletionFeb 2024CompletionApr 2024 - Phase 2Completed
VK2735 for Weight Management Phase 2 (Venture Oral Dosing)
Placebo, VK2735
Weight Loss
NCT06828055Enrollment280StartDec 2024Primary CompletionJun 2025CompletionAug 2025 - Phase 1Completed
A Study to Assess the Pharmacodynamics of VK0214 in Male Subjects With AMN
VK0214
Adrenomyeloneuropathy Form (AMN) of X-linked Adrenoleukodystrophy (X-ALD)
NCT04973657Enrollment24StartJun 2021Primary CompletionOct 2024CompletionNov 2024 - Phase 1Completed
Phase 1 Study to Evaluate the Safety and Tolerability of VK2735
VK2735, Placebo
Weight Loss, NASH
NCT05203237Enrollment92StartDec 2021Primary CompletionNov 2024CompletionDec 2024 - Phase 1Recruiting
A Phase 1 Study of VK2735 in Obese Adults Without Comorbidities
VK2735 Drug, Placebo
Obese Adults
NCT07838740Enrollment270StartNov 2025Primary CompletionMay 2027est.CompletionJul 2027est. - Phase 1Recruiting
A Phase 1 Study of VK3019 in Overweight and Obese Adults Without Comorbidities
SC VK3019, Matching placebo
Obese Adults
NCT07846033Enrollment56StartJul 2026Primary CompletionOct 2026est.CompletionNov 2026est.
| Drug / Therapy | Link | ||
|---|---|---|---|
| Phase 3 | Active, not recruiting | VK2735 | NCT07104383 |
| Phase 3 | Active, not recruiting | VK2735 | NCT07104500 |
| Phase 3 | Not yet recruiting | VK2735, Placebo comparator | NCT07868835 |
| Phase 3 | Not yet recruiting | VK2735 Oral, Placebo Comparator | NCT07868939 |
| Phase 2 | Completed | VK5211, Placebo | NCT02578095 |
| Phase 2 | Completed | VK2809, Placebo | NCT02927184 |
| Phase 2 | Completed | VK2809, Placebos | NCT04173065 |
| Phase 2 | Completed | VK2735, Placebo | NCT06068946 |
| Phase 2 | Completed | Placebo, VK2735 | NCT06828055 |
| Phase 1 | Completed | VK0214 | NCT04973657 |
| Phase 1 | Completed | VK2735, Placebo | NCT05203237 |
| Phase 1 | Recruiting | VK2735 Drug, Placebo | NCT07838740 |
| Phase 1 | Recruiting | SC VK3019, Matching placebo | NCT07846033 |