Voyager Therapeutics, Inc. (VYGR)
Voyager Therapeutics, Inc. operates as a gene therapy company, concentrating its efforts on developing innovative treatments and pioneering advanced platform technologies. Its leading clinical asset, VY-AADC, is presently undergoing an open-label Phase 1 clinical trial for the management of Parkinson's disease. The company's preclinical portfolio is extensive, featuring VY-SOD102 for amyotrophic lateral sclerosis (ALS), VY-HTT01 for Huntington's disease, and VY-FXN01 for Friedreich's ataxia. Additionally, Voyager is pursuing a Tau program aimed at various tauopathies, including Alzheimer's disease, progressive supranuclear palsy, and frontotemporal dementia, alongside initiatives for spinal muscular atrophy. To advance its gene therapy product pipeline, the company has forged strategic collaboration and licensing agreements with key industry players such as Neurocrine Biosciences, Inc., Pfizer Inc., and Novartis Pharma, A.G. These partnerships cover the research, development, and commercialization of adeno-associated virus-based gene therapy products. Voyager Therapeutics, Inc. was founded in 2013 and maintains its corporate headquarters in Cambridge, Massachusetts.
Sector: Biological Products, (No Diagnostic Substances)
Industry: Biotechnology
Voyager Therapeutics, Inc.
Trials need funding. See this company's dilution risk and cash position.
- Phase 3Completed
ALADDIN Study - Phase III: Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation (VP-AD-301)
VP4896
Alzheimer's Disease
NCT00231946Enrollment555StartSep 2005Primary Completion-Completion- - Phase 2Completed
ALADDIN Study: Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation
Leuprolide acetate
Alzheimer Disease
NCT00063310Enrollment90StartMar 2003Primary CompletionFeb 2006CompletionFeb 2006 - Phase 2Completed
Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation (ALADDIN) VP 104 Study
Leuprolide acetate
Alzheimer Disease
NCT00076440Enrollment90StartDec 2003Primary CompletionMar 2007CompletionMar 2007 - Phase 1/2Active, not recruiting
VY7523-102: Randomized, Placebo-Controlled, Double-Blind, Multiple Ascending Dose Study in Participants With Early Alzheimer's Disease
VY7523, Placebo Comparator
Alzheimer's Disease (AD)
NCT06874621Enrollment52StartMar 2025Primary CompletionOct 2026CompletionMay 2027est. - Phase 1Withdrawn
Safety and Tolerability Study With VY-HTT01, in Adults With Early Manifesting Huntington's Disease
Intraparenchymal rAAV1 - (mi)RNA HTT
Huntington Disease
NCT04885114Enrollment0StartJul 2021est.Primary CompletionDec 2024est.CompletionDec 2024est. - Phase 1Recruiting
An Open Label Dose Escalation Study of VY1706 in Participants With Early Alzheimer's Disease
VY1706 Low dose, VY1706 Mid dose
Alzheimer s Disease
NCT07764146Enrollment18StartSep 2026Primary CompletionApr 2029est.CompletionApr 2029est. - Not applicableRecruiting
Access Cannulation Trial II
VenaSure
Dialysis; Complications, Vascular Access Complication
NCT05490225Enrollment100StartApr 2025Primary CompletionMar 2027est.CompletionMar 2027est.
| Drug / Therapy | Link | ||
|---|---|---|---|
| Phase 3 | Completed | VP4896 | NCT00231946 |
| Phase 2 | Completed | Leuprolide acetate | NCT00063310 |
| Phase 2 | Completed | Leuprolide acetate | NCT00076440 |
| Phase 1/2 | Active, not recruiting | VY7523, Placebo Comparator | NCT06874621 |
| Phase 1 | Withdrawn | Intraparenchymal rAAV1 - (mi)RNA HTT | NCT04885114 |
| Phase 1 | Recruiting | VY1706 Low dose, VY1706 Mid dose | NCT07764146 |
| Not applicable | Recruiting | VenaSure | NCT05490225 |