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Xenon Pharmaceuticals Inc. (XENE)

Xenon Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company dedicated to discovering and advancing innovative treatments for individuals living with neurological disorders. The company operates primarily from its headquarters in Burnaby, Canada. Its robust clinical pipeline showcases several promising candidates: XEN496, an activator of Kv7 potassium channels, is currently in Phase III clinical trials for KCNQ2 developmental and epileptic encephalopathy. Another Kv7 potassium channel activator, XEN1101, is progressing through Phase II trials, targeting epilepsy and a range of other neurological conditions. The portfolio also includes NBI-921352, a selective inhibitor of the Nav1.6 sodium channel, which is undergoing Phase II clinical evaluation for SCN8A developmental and epileptic encephalopathy, alongside investigations for adult focal epilepsy and other potential indications. Furthermore, XEN007, a central nervous system-acting calcium channel modulator, is also in Phase II development. Beyond its internal development, Xenon Pharmaceuticals has established strategic collaborations. This includes a licensing and development agreement with Neurocrine Biosciences, Inc. focused on epilepsy treatments, and a partnership with Flexion Therapeutics, Inc. to advance PCRX301 (also known as XEN402), a Nav1.7 inhibitor, for post-operative pain management. Established in 1996, the company continues its mission to address significant unmet medical needs in neurology.

Sector: Pharmaceutical Preparations

Industry: Biotechnology

Xenon Pharmaceuticals Inc. logo

Xenon Pharmaceuticals Inc.

NASDAQ:XENEHealthcare
-0.35%$37.41
AH$37.41+0.00%vs close
Mkt Cap$3.62B
Float90.76M
O/S96.84M
Vol
$ Vol
RVOL
Inst Own-
SI8.1%
Earnings
Dilution
Financials Summary
Revenue$7.5M
Net Income-$345.91M
Total Assets$981.67M
Free Cash Flow-$279.92M
Debt & Equity
Debt 1%
Equity 99%
Total Debt$7.94M
Total Equity$581.76M
Shares Outstanding
Short Interest
Split History

No splits on record

Nothing in XENE's public trading history: no forward or reverse split has affected the share count.

Balance Sheet Details
Assets$981.67M
Liabilities$399.91M
Accounts Receivable$1.37M
Accounts Payable$3.88M
Inventory$0
PP&E (Net)$15.35M
Goodwill$0
Intangible Assets$0
Income Statement
PeriodFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015FY 2014FY 2013FY 2012FY 2011
CurrencyUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSD
Period Ending2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Revenue$7.5M$0$0$9.43M$18.44M$32.17M$6.83M$0$311K$1.8M$15.58M$28.37M$27.36M$14.31M$6.92M
YoY Growth----48.8%-42.7%371.0%---82.8%-88.4%-45.1%3.7%91.2%106.8%-
Cost of Revenue$2.54M$2.56M$167.51M$0$0$0$0$6M$25.57M$1.11M$2.76M$5.9M$6.21M$7.32M$0
Gross Profit$4.96M-$2.56M-$167.51M$9.43M$18.44M$32.17M$6.83M-$6M-$25.26M$689K$12.81M$22.47M$21.15M$6.99M$6.92M
Gross Margin66.1%--100.0%100.0%100.0%100.0%--8122.8%38.2%82.3%79.2%77.3%48.8%100.0%
Research and Development$300.94M$210.39M$167.51M$105.77M$75.46M$50.52M$38.84M$23.63M$25.57M$19.83M$15.15M$11.77M$12.3M$10.46M$12.3M
Selling, General, and Administrative$79.63M$68.9M$46.54M$32.81M$21.97M$12.94M$10.8M$8.38M$7.31M$6.79M$9.79M$5.5M$5.34M$7.01M$6.73M
Other-$2.54M-$2.56M-$167.51M$0$0$0$0$0$0$0-$6.39M$0$0$0$0
Total Operating Expenses$378.03M$276.74M$46.54M$138.58M$97.43M$63.47M$49.65M$32.02M$32.89M$26.62M$24.94M$17.26M$17.64M$17.46M$19.03M
Operating Income (EBIT)-$373.07M-$279.3M-$214.05M-$129.14M-$78.99M-$31.3M-$42.82M-$38.02M-$32.58M-$24.82M-$9.36M$11.11M$9.71M-$3.15M-$12.11M
Operating Margin-4974.3%---1368.9%-428.4%-97.3%-627.0%--10474.3%-1376.4%-60.1%39.1%35.5%-22.0%-175.1%
Interest Expense$0$0$0$0$0$484K$1.43M$1.39M$0$0$0$0$64K$93K$91K
Interest Income$26.83M$41.94M$27.62M$8.71M$466K$2.28M$2.35M$1.22M$477K$504K$542K$568K$338K$144K$153K
Other Income (Expense)$28.18M$40.88M$31.37M$3.89M$105K$2.21M$1.2M$6.4M$1.87M$1.82M-$6.39M$1.91M$2.32M-$1.15M$122K
Income Before Tax (EBT)-$344.89M-$238.42M-$182.69M-$125.25M-$78.89M-$29.09M-$41.62M-$34.5M-$30.7M-$23M-$15.75M$13.02M$12.03M-$4.3M-$11.99M
Income Tax Expense$1.02M-$4.09M-$292K$118K-$6K-$257K-$23K$4.91M$0$0$0$0$64K$0$91K
Net Income-$345.91M-$234.33M-$182.39M-$125.37M-$78.88M-$28.84M-$41.59M-$34.5M-$30.7M-$23M-$15.75M$13.02M$12.03M-$4.3M-$11.99M
Net Income Margin-4612.1%---1328.9%-427.8%-89.7%-609.1%--9872.7%-1275.5%-101.1%45.9%44.0%-30.1%-173.3%
Supplementary Data
EPS-4.36-3.01-2.73-2.06-1.77-0.83-1.54-1.78-1.71-1.48-1.100.940.42-3.23-9.02
Diluted EPS-4.36-3.01-2.73-2.06-1.77-0.83-1.54-1.78-1.71-1.48-1.100.940.39-3.23-9.02
Weighted Average OS79.25M77.89M66.89M60.54M43.63M34.54M25.94M19.43M17.99M15.49M14.28M13.88M9.09M1.33M1.33M
EBITDA-$342.35M-$235.86M-$210.51M-$127.74M-$78.09M-$27.97M-$39.76M-$32.54M-$30.05M-$23.95M-$8.32M$11.84M$10.42M-$3.42M-$10.77M
EBITDA Margin-4564.7%---1354.0%-423.5%-86.9%-582.1%--9664.0%-1328.5%-53.4%41.7%38.1%-23.9%-155.7%
Balance Sheet
PeriodFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015FY 2014FY 2013FY 2012
CurrencyUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSD
Period Ending2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-31
Assets
Current Assets
Cash and Cash Equivalents$199.16M$142.71M$148.64M$57.24M$175.69M$45.01M$24.75M$67.75M$20.49M$17.09M$58.65M$72.03M$37.95M$60.16M
Short-Term Investments$349.72M$484.19M$489.44M$534.85M$376.09M$131.99M$116.6M$51.55M$23.18M$47.05M$0$12.02M$11.33M$0
Cash and Short-Term Investments$548.89M$626.9M$638.08M$592.09M$551.77M$177M$141.36M$119.31M$43.67M$64.15M$58.65M$84.04M$49.28M$60.16M
Accounts Receivable$1.37M$1.47M$874K$986K$2.77M$1.82M$813K$151K$438K$200K$315K$215K$440K$392K
Inventory$0$0$0$0$0$0$0$0$0$0$0$0$0$0
Other Current Assets$10.39M$6.89M$6.01M$7.22M$0$0$0$0$0$0$0$0$0$149K
Total Current Assets$560.65M$635.26M$644.96M$600.3M$559.02M$181.78M$144.87M$121.44M$44.82M$65.67M$60.87M$84.94M$49.87M$60.7M
Long-Term Assets
Property, Plant & Equipment Net$15.35M$18.22M$18.85M$16.91M$12.52M$6.88M$2.59M$991K$1.07M$1.4M$1.99M$2.48M$1.88M$2.6M
Goodwill$0$0$0$0$0$0$0$0$0$0$0$0$0$0
Intangible Assets$0$0$0$0$0$0$0$0$0$0$0$0$0$0
Long-Term Investments$37.15M$127.5M$292.79M$128.68M$0$0$0$0$0$0$0$0$0$0
Deferred Tax Assets$361.37M$9.67M$802K$509K$465K$523K$238K$105K$0$0$0$0$0$0
Other Long-Term Assets$7.15M$7.5M$7.4M$7.75M$0$0$0-$105K$230K$408K$1.09M$0$2.74M-$2.6M
Total Long-Term Assets$421.02M$162.88M$319.84M$153.85M$12.99M$7.4M$2.83M$991K$1.3M$1.81M$3.08M$2.48M$4.62M$2.6M
Other Assets$0$0$0$0$0$0$0$0$0$0$0$0$0$0
Total Assets$981.67M$798.14M$964.8M$754.15M$572.01M$189.19M$147.7M$122.43M$46.12M$67.49M$63.95M$87.42M$54.49M$63.3M
Liabilities
Current Liabilities
Accounts Payable$3.88M$5.07M$8.6M$8.49M$3.82M$3.04M$2.47M$665K$1.25M$1.46M$1.09M$553K$391K$821K
Short-Term Debt$1.53M$0$0$0$0$0$4.65M$0$700K$0$0$0$0$0
Current Income Tax Payable$0$5.69M$0$0$0$0$0$0$0$0$0$0$0$0
Current Unearned Revenue$0$0$0$0$0$3.64M$29.74M-$15.01M$0$0$157K$11.62M$15.92M$17.02M
Other Current Liabilities$21.6M$9.93M$347K$5.82M$5.94M$2.86M$3.45M$1.73M$44K$59K$762K$1.03M$1.37M$244K
Total Current Liabilities$41.79M$35.59M$27.27M$22.7M$14.32M$14.78M$43.38M$4.12M$4.08M$3.52M$2.78M$14.29M$18.2M$19.2M
Long-Term Liabilities
Long-Term Debt$0$0$0$0$0$0$10.89M$15.01M$6.1M$0$0$0$0$1.67M
Long-Term Unearned Revenue$0$0$0$0$0$0$709K$0$0$0$0$157K$11.89M$29.64M
Long-Term Deferred Tax Liabilities$348.51M$0$0$0$0$0$0$0$0$0$0$0$0$0
Other Long-Term Liabilities$3.2M$0$0$0$0$0$0$0$0$0$133K$196K$282K$184K
Total Long-Term Liabilities$358.12M$7.65M$9.6M$9.95M$7.65M$3.05M$12.34M$15.01M$6.1M$70K$133K$353K$12.17M$31.49M
Other Liabilities$0$0$0$0$0$0$0$0$0$0$0$0$0$0
Total Liabilities$399.91M$43.24M$36.88M$32.65M$21.97M$17.83M$55.72M$19.13M$10.19M$3.59M$2.92M$14.64M$30.37M$50.68M
Stockholders' Equity
Preferred Stock$0$0$0$0$7.73M$7.73M$7.73M$7.73M$0$173.25M$148.63M$0$102.49M$102.49M
Common Stock$1.6B$1.46B$1.44B$1.07B$783.17M$397.75M$294.24M$265.92M$173.84M$173.25M$148.63M$147.16M$6.15M$6.01M
Retained Earnings-$1.25B-$899.47M-$665.14M-$482.75M-$357.37M-$278.49M-$249.66M-$207.88M-$173.39M-$142.68M-$119.69M-$103.73M-$116.75M-$128.78M
Comprehensive Income & Other$335K-$1.61M-$77K-$3M-$990K-$990K-$990K-$990K-$990K-$990K-$990K-$990K$2.51M$3.75M
Other Stockholders' Equity$228.57M$197.54M$156.69M$139.11M$124.24M$52.1M$47.39M$45.26M$35.48M$33.34M$32.09M$29.36M$134.72M$135.4M
Total Equity$581.76M$754.9M$927.92M$721.5M$550.03M$171.35M$91.98M$103.3M$35.93M$63.9M$61.03M$72.78M$24.12M$12.62M
Minority Interest$0$0$0$0$0$0$0$0$0$0$0$0$0$0
Total Liabilities and Equity$981.67M$798.14M$964.8M$754.15M$572.01M$189.19M$147.7M$122.43M$46.12M$67.49M$63.95M$87.42M$54.49M$63.3M
Supplementary Data
Total Debt$7.94M$9.02M$10.9M$10.44M$8.26M$3.31M$16.45M$15.01M$6.8M$0$0$0$0$1.67M
Net Debt-$191.22M-$133.7M-$137.74M-$46.81M-$167.43M-$41.69M-$8.3M-$52.74M-$13.68M-$17.09M-$58.65M-$72.03M-$37.95M-$58.5M
Cash Flow Statement
PeriodFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015FY 2014FY 2013FY 2012FY 2011
CurrencyUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSD
Period Ending2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-312011-12-31
Operating Activities
Net Income-$345.91M-$234.33M-$182.39M-$125.37M-$78.88M-$28.84M-$41.59M-$34.5M-$30.7M-$23M-$15.75M$13.02M$12.03M-$4.3M-$11.99M
Depreciation & Amortization$2.54M$2.56M$3.54M$1.41M$906K$644K$429K$586K$649K$864K$1.04M$738K$705K$786K$1.13M
Deferred Income Tax-$3.2M-$8.86M-$292K-$44K$58K-$285K-$133K$646K-$1.47M-$1.3M$6.9M$72K$83K$996K-$88K
Stock-Based Compensation$53.71M$50.72M$32.37M$20.38M$10.02M$5.68M$2.92M$2.63M$2.24M$2.16M$3.73M$760K$648K$414K$447K
Changes in Working Capital:
  Accounts Receivable$104K-$614K$130K$1.76M-$459K-$1.03M-$653K$175K-$232K$121K-$107K$209K-$76K$11.23M-$11.01M
  Inventory$0$0$0$0-$2.97M-$2.02M-$4.54M-$783K$613K$571K$0-$573K$0$0$0
  Accounts Payable$5.51M$8.53M$3.93M$8.06M$2.97M$2.02M$4.54M$783K-$3K$547K$80K$518K$0$0$0
  Other Working Capital-$1.25M-$2.2M$1.57M-$10.49M-$2.19M-$25.06M$34.17M-$145K$178K$529K-$13.85M-$14.41M-$16.6M$36.19M$7.74M
Total Working Capital Change$4.36M$5.71M$5.63M-$676K-$2.65M-$26.09M$33.52M$30K$556K$1.77M-$13.96M-$14.26M-$16.68M$47.42M-$3.27M
Other Non-Cash Items$9.38M$2.81M-$4.19M$5.88M$1.05M$766K$223K-$4.11M$11K-$63K-$63K-$66K-$115K$260K$78K
Net Cash from Operating-$279.12M-$181.39M-$145.33M-$98.43M-$69.5M-$48.12M-$4.63M-$34.72M-$28.73M-$19.57M-$18.1M$266K-$3.32M$45.57M-$13.69M
Investing Activities
Capital Expenditures-$799K-$3.08M-$5.62M-$2.89M-$2.05M-$2.64M-$1.24M-$507K-$315K-$279K-$551K-$1.53M-$156K-$526K-$290K
Acquisitions$0$0$0$296M-$144.75M-$214.71M-$75.44M-$48.52M-$52.62M$0$0-$13.54M$0$0$0
Purchases of Investments-$355.66M-$532.27M-$793.91M-$551.14M-$389.47M-$228.9M-$140.49M-$77M-$28.01M-$47.56M$0-$15.25M-$17.88M$0$0
Sales of Investments$574.45M$700.34M$682.35M$258.03M$144.75M$214.71M$75.44M$48.52M$52.62M$0$10.74M$13.54M$6.55M$1.01M$14.18M
Other Investing Activities$0$0$0-$296M$144.75M$214.71M$75.44M$48.52M$52.62M-$47.56M$10.74M$13.54M$10K$7K$0
Net Cash from Investing$218M$165M-$117.17M-$296M-$246.77M-$16.82M-$66.29M-$28.99M$24.29M-$47.84M$10.19M-$3.24M-$11.47M$491K$13.89M
Financing Activities
Debt Repaid-----$16.74M--$8.45M-$6.89M---$1.7M--
Common Stock Issuance$117.11M$12.08M$353.49M$277.77M$447.28M$102.46M$27.4M$102.85M$177K$23.83M$278K$42.64M$49K$0$2K
Common Stock Repurchases$0$0$0$0$0$0$0$0$0$0$0$0$0$0$0
Dividends Paid$0$0$0$0$0$0$0$0$0$0$0$0$0$0$0
Other Financing Activities$0$47K$35K$705K$260K$82K$122K$288K$177K$132K$0-$1.52M-$2.74M$0$0
Net Cash from Financing$117.11M$12.13M$353.52M$278.47M$447.54M$85.8M$27.52M$111.59M$7.07M$23.96M$278K$41.12M-$4.39M$0$2K
Forex Effect$458K-$1.67M$376K-$2.48M-$592K-$593K$406K-$612K$753K$1.89M-$5.74M-$4.07M-$3.03M$170K-$314K
Net Change in Cash$56.45M-$5.93M$91.4M-$118.45M$130.68M$20.25M-$43M$47.27M$3.39M-$41.56M-$13.38M$34.08M-$22.21M$46.23M-$112K
Supplementary Data
Operating Cash Flow-$279.12M-$181.39M-$145.33M-$98.43M-$69.5M-$48.12M-$4.63M-$34.72M-$28.73M-$19.57M-$18.1M$266K-$3.32M$45.57M-$13.69M
Capital Expenditure-$799K-$3.08M-$5.62M-$2.89M-$2.05M-$2.64M-$1.24M-$507K-$315K-$279K-$551K-$1.53M-$156K-$526K-$290K
Free Cash Flow-$279.92M-$184.46M-$150.94M-$101.32M-$71.55M-$50.76M-$5.87M-$35.23M-$29.04M-$19.85M-$18.65M-$1.26M-$3.48M$45.05M-$13.98M
Cash at Beginning$142.71M$148.64M$57.24M$175.69M$45.01M$24.75M$67.75M$20.49M$17.09M$58.65M$72.03M$37.95M$60.16M$13.93M$14.04M
Cash at End$199.16M$142.71M$148.64M$57.24M$175.69M$45.01M$24.75M$67.75M$20.49M$17.09M$58.65M$72.03M$37.95M$60.16M$13.93M