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Yarrow Bioscience, Inc. (YARW)

Yarrow Bioscience is a clinical-stage biotechnology company focused on developing transformative therapies for autoimmune thyroid diseases. The Company's lead product candidate, YB-101, is a potential first-in-class anti-thyroid stimulating hormone receptor (TSHR) monoclonal antibody designed to directly and rapidly disrupt the central mechanism of both Graves' disease (GD) and thyroid eye disease (TED).

Sector: Pharmaceutical Preparations

Industry: Biotechnology

Yarrow Bioscience Inc logo

Yarrow Bioscience Inc

NASDAQ:YARWHealthcare
-0.50%$19.90
AH$19.90+0.00%vs close
Mkt Cap$185.16M
Float9.3M
O/S9.3M
Vol
$ Vol
RVOL
Inst Own2.9%
Earnings
Div Yield101.00%
Dilution
Phase Distribution
33 lead-sponsored trials·1 active·27 completed
Phase 16
Phase 1/21
Phase 217
Phase 39
(5 more as collaborator)
Status Overview
Recruiting1
Completed27
Stopped5

Trials need funding. See this company's dilution risk and cash position.

Clinical Trials
Sponsor role
Status
Phase
  • Phase 3
    Completed

    A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne

    FMX-101, 4% minocycline foam, Vehicle Foam

    Acne Vulgaris

    Enrollment
    466
    Start
    May 2016
    Primary Completion
    Oct 2017
    Completion
    Oct 2017
    NCT02815267
  • Phase 3
    Completed

    A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne

    FMX-101, 4% minocycline foam, Vehicle Foam

    Acne Vulgaris

    Enrollment
    495
    Start
    May 2016
    Primary Completion
    Oct 2017
    Completion
    Oct 2017
    NCT02815280
  • Phase 3
    Completed

    A Study (Study 1) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea

    FMX103 minocycline foam 1.5%, Vehicle foam

    Facial Papulopustular Rosacea

    Enrollment
    751
    Start
    Jun 2017
    Primary Completion
    Aug 2018
    Completion
    Sep 2018
    NCT03142451
  • Phase 3
    Completed

    A Study to Evaluate the Efficacy and Safety of Topical Administration of FMX101 in the Treatment of Moderate-to-Severe Acne Vulgaris

    FMX101, Vehicle Foam

    Acne Vulgaris

    Enrollment
    1,488
    Start
    Jul 2017
    Primary Completion
    Sep 2018
    Completion
    Sep 2018
    NCT03271021
  • Phase 3
    Completed

    A Study to Evaluate the Long-Term Safety of Topical Administration of FMX103 in the Treatment of Moderate to Severe Papulopustular Rosacea

    FMX103 1.5%

    Papulopustular Rosacea

    Enrollment
    504
    Start
    Sep 2017
    Primary Completion
    Jan 2019
    Completion
    Jan 2019
    NCT03276936
  • Phase 3
    Terminated

    Study of the Long Term Safety of Serlopitant for the Treatment of Pruritus (Itch)

    5 mg Serlopitant Tablets

    Pruritus, Prurigo Nodularis +2

    Enrollment
    558
    Start
    Mar 2018
    Primary Completion
    Apr 2020
    Completion
    Jun 2020
    NCT03540160
  • Phase 3
    Completed

    Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis

    5mg Serlopitant Tablets, Placebo Tablets

    Pruritus, Prurigo Nodularis

    Enrollment
    285
    Start
    May 2018
    Primary Completion
    Jan 2020
    Completion
    Feb 2020
    NCT03546816
  • Phase 3
    Completed

    Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis

    5mg Serlopitant Tablets, Placebo Tablets

    Pruritus, Prurigo Nodularis

    Enrollment
    295
    Start
    Aug 2018
    Primary Completion
    Jan 2020
    Completion
    Feb 2020
    NCT03677401
  • Phase 3
    Completed

    A Study (Study 2) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea

    FMX103 minocycline foam 1.5%, Vehicle foam

    Facial Papulopustular Rosacea

    Enrollment
    771
    Start
    Jun 2017
    Primary Completion
    Jul 2018
    Completion
    Jul 2018
    NCT04608500
  • Phase 2
    Completed

    Safety and Efficacy of MK0594 to Treat Overactive Bladder (0594-003)

    MK0594

    Urinary Incontinence, Overactive Bladder

    Enrollment
    557
    Start
    Feb 2006
    Primary Completion
    Aug 2007
    Completion
    Sep 2007
    NCT00290563
  • Phase 2
    Terminated

    A Study of MK0594 in Patients With Alcohol Dependence (0594-020)

    Comparator: MK0594 5 mg/day, Comparator: MK0594 1 mg/day

    Alcohol Dependence

    Enrollment
    162
    Start
    Feb 2009
    Primary Completion
    Mar 2010
    Completion
    Mar 2010
    NCT00835718
  • Phase 2
    Terminated

    Study to Evaluate the Safety and Efficacy of Topical Minocycline FXFM244 in Rosacea Patients

    Topical Minocycline Foam FXFM244

    Rosacea

    Enrollment
    21
    Start
    Jun 2010
    Primary Completion
    Mar 2014
    Completion
    -
    NCT01134991
  • Phase 2
    Completed

    Study to Evaluate the Safety and Efficacy of Topical Minocycline FXFM244 in Impetigo Patients

    Topical Minocycline Foam FXFM244

    Impetigo

    Enrollment
    32
    Start
    Aug 2010
    Primary Completion
    Mar 2012
    Completion
    Apr 2012
    NCT01171326
  • Phase 2
    Completed

    Clinical Study to Evaluate Tolerability and Safety of FXFM244 and to Monitor Clinical Effect in Acne Vulgaris Patients

    Topical Minocycline Foam FXFM244

    Acne Vulgaris

    Enrollment
    150
    Start
    Jan 2012
    Primary Completion
    Jun 2013
    Completion
    Jul 2013
    NCT01362010
  • Phase 2
    Completed

    VPD-737 for Treatment of Chronic Pruritus

    VPD-737, Placebo

    Chronic Pruritus

    Enrollment
    257
    Start
    Oct 2013
    Primary Completion
    Dec 2014
    Completion
    Dec 2014
    NCT01951274
  • Phase 2
    Completed

    A Randomized Placebo-Controlled Study of the Neurokinin-1 (NK1) Receptor Antagonist Serlopitant Prurigo Nodularis (PN)

    serlopitant, Placebo

    Prurigo Nodularis

    Enrollment
    128
    Start
    Jul 2014
    Primary Completion
    May 2016
    Completion
    Jun 2016
    NCT02196324
  • Phase 2
    Completed

    Safety, Tolerability and Efficacy Study of Doxycycline Foam for the Prevention of EGFRI Skin Toxicity in Cancer Patients

    FDX104 (4% Doxycycline)

    Rash Due to Epidermal Growth Factor Receptor Inhibitors

    Enrollment
    24
    Start
    Oct 2014
    Primary Completion
    Oct 2015
    Completion
    Oct 2015
    NCT02239731
  • Phase 2
    Completed

    Safety and Efficacy Study of a Topical Minocycline Foam in Patients With Papulopustular Rosacea

    FMX-103 1.5%, FMX-103 3%

    Rosacea, Papulopustular Rosacea

    Enrollment
    233
    Start
    Sep 2015
    Primary Completion
    Aug 2016
    Completion
    Aug 2016
    NCT02601963
  • Phase 2
    Completed

    Study of the Efficacy, Safety, and Tolerability of Serlopitant for Pruritus (Itch) in Atopic Dermatitis

    Serlopitant High Dose, Placebo Oral Tablet

    Pruritus, Atopic Dermatitis

    Enrollment
    484
    Start
    Nov 2016
    Primary Completion
    Jan 2018
    Completion
    Feb 2018
    NCT02975206
  • Phase 2
    Terminated

    Study of the Efficacy, Safety & Tolerability of Serlopitant for Pruritus (Itch) After Burn Injury

    Serlopitant, Placebo

    Pruritus, Burns

    Enrollment
    1
    Start
    Nov 2016
    Primary Completion
    Jan 2017
    Completion
    Jan 2017
    NCT02975271
  • Phase 2
    Completed

    Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Refractory Chronic Cough

    5 mg Serlopitant Tablets, Matching Placebo Tablets

    Refractory Chronic Cough

    Enrollment
    185
    Start
    Oct 2017
    Primary Completion
    Aug 2018
    Completion
    Sep 2018
    NCT03282591
  • Phase 2
    Completed

    Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Plaque Psoriasis

    5 mg Serlopitant Tablets, Matching Placebo Tablets

    Pruritus, Psoriasis

    Enrollment
    204
    Start
    Nov 2017
    Primary Completion
    Oct 2018
    Completion
    Nov 2018
    NCT03343639
  • Phase 2
    Completed

    Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Chronic Pruritus of Unknown Origin

    5 mg Serlopitant Tablets, Matching Placebo Tablets

    Pruritus

    Enrollment
    233
    Start
    Jan 2019
    Primary Completion
    Dec 2019
    Completion
    Jan 2020
    NCT03841331
  • Phase 2
    Completed

    A Study to Compare FCD105 Foam to Minocycline 3% Foam, Adapalene 0.3% Foam and Vehicle Foam.

    3% Minocycline Foam, 0.3% Adapalene Foam

    Acne Vulgaris

    Enrollment
    446
    Start
    Sep 2019
    Primary Completion
    Feb 2020
    Completion
    Mar 2020
    NCT04104685
  • Phase 2
    Terminated

    A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of VYN201 Gel in Subjects With Non-segmental Vitiligo.

    VYN201 Gel, Vehicle Gel

    Non-segmental Vitiligo

    Enrollment
    205
    Start
    Jun 2024
    Primary Completion
    Jul 2025
    Completion
    Sep 2025
    NCT06493578

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