Yarrow Bioscience, Inc. (YARW)
Yarrow Bioscience is a clinical-stage biotechnology company focused on developing transformative therapies for autoimmune thyroid diseases. The Company's lead product candidate, YB-101, is a potential first-in-class anti-thyroid stimulating hormone receptor (TSHR) monoclonal antibody designed to directly and rapidly disrupt the central mechanism of both Graves' disease (GD) and thyroid eye disease (TED).
Sector: Pharmaceutical Preparations
Industry: Biotechnology
Yarrow Bioscience Inc
Trials need funding. See this company's dilution risk and cash position.
- Phase 3Completed
A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne
FMX-101, 4% minocycline foam, Vehicle Foam
Acne Vulgaris
NCT02815267Enrollment466StartMay 2016Primary CompletionOct 2017CompletionOct 2017 - Phase 3Completed
A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne
FMX-101, 4% minocycline foam, Vehicle Foam
Acne Vulgaris
NCT02815280Enrollment495StartMay 2016Primary CompletionOct 2017CompletionOct 2017 - Phase 3Completed
A Study (Study 1) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea
FMX103 minocycline foam 1.5%, Vehicle foam
Facial Papulopustular Rosacea
NCT03142451Enrollment751StartJun 2017Primary CompletionAug 2018CompletionSep 2018 - Phase 3Completed
A Study to Evaluate the Efficacy and Safety of Topical Administration of FMX101 in the Treatment of Moderate-to-Severe Acne Vulgaris
FMX101, Vehicle Foam
Acne Vulgaris
NCT03271021Enrollment1,488StartJul 2017Primary CompletionSep 2018CompletionSep 2018 - Phase 3Completed
A Study to Evaluate the Long-Term Safety of Topical Administration of FMX103 in the Treatment of Moderate to Severe Papulopustular Rosacea
FMX103 1.5%
Papulopustular Rosacea
NCT03276936Enrollment504StartSep 2017Primary CompletionJan 2019CompletionJan 2019 - Phase 3Terminated
Study of the Long Term Safety of Serlopitant for the Treatment of Pruritus (Itch)
5 mg Serlopitant Tablets
Pruritus, Prurigo Nodularis +2
NCT03540160Enrollment558StartMar 2018Primary CompletionApr 2020CompletionJun 2020 - Phase 3Completed
Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis
5mg Serlopitant Tablets, Placebo Tablets
Pruritus, Prurigo Nodularis
NCT03546816Enrollment285StartMay 2018Primary CompletionJan 2020CompletionFeb 2020 - Phase 3Completed
Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis
5mg Serlopitant Tablets, Placebo Tablets
Pruritus, Prurigo Nodularis
NCT03677401Enrollment295StartAug 2018Primary CompletionJan 2020CompletionFeb 2020 - Phase 3Completed
A Study (Study 2) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea
FMX103 minocycline foam 1.5%, Vehicle foam
Facial Papulopustular Rosacea
NCT04608500Enrollment771StartJun 2017Primary CompletionJul 2018CompletionJul 2018 - Phase 2Completed
Safety and Efficacy of MK0594 to Treat Overactive Bladder (0594-003)
MK0594
Urinary Incontinence, Overactive Bladder
NCT00290563Enrollment557StartFeb 2006Primary CompletionAug 2007CompletionSep 2007 - Phase 2Terminated
A Study of MK0594 in Patients With Alcohol Dependence (0594-020)
Comparator: MK0594 5 mg/day, Comparator: MK0594 1 mg/day
Alcohol Dependence
NCT00835718Enrollment162StartFeb 2009Primary CompletionMar 2010CompletionMar 2010 - Phase 2Terminated
Study to Evaluate the Safety and Efficacy of Topical Minocycline FXFM244 in Rosacea Patients
Topical Minocycline Foam FXFM244
Rosacea
NCT01134991Enrollment21StartJun 2010Primary CompletionMar 2014Completion- - Phase 2Completed
Study to Evaluate the Safety and Efficacy of Topical Minocycline FXFM244 in Impetigo Patients
Topical Minocycline Foam FXFM244
Impetigo
NCT01171326Enrollment32StartAug 2010Primary CompletionMar 2012CompletionApr 2012 - Phase 2Completed
Clinical Study to Evaluate Tolerability and Safety of FXFM244 and to Monitor Clinical Effect in Acne Vulgaris Patients
Topical Minocycline Foam FXFM244
Acne Vulgaris
NCT01362010Enrollment150StartJan 2012Primary CompletionJun 2013CompletionJul 2013 - Phase 2Completed
VPD-737 for Treatment of Chronic Pruritus
VPD-737, Placebo
Chronic Pruritus
NCT01951274Enrollment257StartOct 2013Primary CompletionDec 2014CompletionDec 2014 - Phase 2Completed
A Randomized Placebo-Controlled Study of the Neurokinin-1 (NK1) Receptor Antagonist Serlopitant Prurigo Nodularis (PN)
serlopitant, Placebo
Prurigo Nodularis
NCT02196324Enrollment128StartJul 2014Primary CompletionMay 2016CompletionJun 2016 - Phase 2Completed
Safety, Tolerability and Efficacy Study of Doxycycline Foam for the Prevention of EGFRI Skin Toxicity in Cancer Patients
FDX104 (4% Doxycycline)
Rash Due to Epidermal Growth Factor Receptor Inhibitors
NCT02239731Enrollment24StartOct 2014Primary CompletionOct 2015CompletionOct 2015 - Phase 2Completed
Safety and Efficacy Study of a Topical Minocycline Foam in Patients With Papulopustular Rosacea
FMX-103 1.5%, FMX-103 3%
Rosacea, Papulopustular Rosacea
NCT02601963Enrollment233StartSep 2015Primary CompletionAug 2016CompletionAug 2016 - Phase 2Completed
Study of the Efficacy, Safety, and Tolerability of Serlopitant for Pruritus (Itch) in Atopic Dermatitis
Serlopitant High Dose, Placebo Oral Tablet
Pruritus, Atopic Dermatitis
NCT02975206Enrollment484StartNov 2016Primary CompletionJan 2018CompletionFeb 2018 - Phase 2Terminated
Study of the Efficacy, Safety & Tolerability of Serlopitant for Pruritus (Itch) After Burn Injury
Serlopitant, Placebo
Pruritus, Burns
NCT02975271Enrollment1StartNov 2016Primary CompletionJan 2017CompletionJan 2017 - Phase 2Completed
Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Refractory Chronic Cough
5 mg Serlopitant Tablets, Matching Placebo Tablets
Refractory Chronic Cough
NCT03282591Enrollment185StartOct 2017Primary CompletionAug 2018CompletionSep 2018 - Phase 2Completed
Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Plaque Psoriasis
5 mg Serlopitant Tablets, Matching Placebo Tablets
Pruritus, Psoriasis
NCT03343639Enrollment204StartNov 2017Primary CompletionOct 2018CompletionNov 2018 - Phase 2Completed
Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Chronic Pruritus of Unknown Origin
5 mg Serlopitant Tablets, Matching Placebo Tablets
Pruritus
NCT03841331Enrollment233StartJan 2019Primary CompletionDec 2019CompletionJan 2020 - Phase 2Completed
A Study to Compare FCD105 Foam to Minocycline 3% Foam, Adapalene 0.3% Foam and Vehicle Foam.
3% Minocycline Foam, 0.3% Adapalene Foam
Acne Vulgaris
NCT04104685Enrollment446StartSep 2019Primary CompletionFeb 2020CompletionMar 2020 - Phase 2Terminated
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of VYN201 Gel in Subjects With Non-segmental Vitiligo.
VYN201 Gel, Vehicle Gel
Non-segmental Vitiligo
NCT06493578Enrollment205StartJun 2024Primary CompletionJul 2025CompletionSep 2025
| Drug / Therapy | Link | ||
|---|---|---|---|
| Phase 3 | Completed | FMX-101, 4% minocycline foam, Vehicle Foam | NCT02815267 |
| Phase 3 | Completed | FMX-101, 4% minocycline foam, Vehicle Foam | NCT02815280 |
| Phase 3 | Completed | FMX103 minocycline foam 1.5%, Vehicle foam | NCT03142451 |
| Phase 3 | Completed | FMX101, Vehicle Foam | NCT03271021 |
| Phase 3 | Completed | FMX103 1.5% | NCT03276936 |
| Phase 3 | Terminated | 5 mg Serlopitant Tablets | NCT03540160 |
| Phase 3 | Completed | 5mg Serlopitant Tablets, Placebo Tablets | NCT03546816 |
| Phase 3 | Completed | 5mg Serlopitant Tablets, Placebo Tablets | NCT03677401 |
| Phase 3 | Completed | FMX103 minocycline foam 1.5%, Vehicle foam | NCT04608500 |
| Phase 2 | Completed | MK0594 | NCT00290563 |
| Phase 2 | Terminated | Comparator: MK0594 5 mg/day, Comparator: MK0594 1 mg/day | NCT00835718 |
| Phase 2 | Terminated | Topical Minocycline Foam FXFM244 | NCT01134991 |
| Phase 2 | Completed | Topical Minocycline Foam FXFM244 | NCT01171326 |
| Phase 2 | Completed | Topical Minocycline Foam FXFM244 | NCT01362010 |
| Phase 2 | Completed | VPD-737, Placebo | NCT01951274 |
| Phase 2 | Completed | serlopitant, Placebo | NCT02196324 |
| Phase 2 | Completed | FDX104 (4% Doxycycline) | NCT02239731 |
| Phase 2 | Completed | FMX-103 1.5%, FMX-103 3% | NCT02601963 |
| Phase 2 | Completed | Serlopitant High Dose, Placebo Oral Tablet | NCT02975206 |
| Phase 2 | Terminated | Serlopitant, Placebo | NCT02975271 |
| Phase 2 | Completed | 5 mg Serlopitant Tablets, Matching Placebo Tablets | NCT03282591 |
| Phase 2 | Completed | 5 mg Serlopitant Tablets, Matching Placebo Tablets | NCT03343639 |
| Phase 2 | Completed | 5 mg Serlopitant Tablets, Matching Placebo Tablets | NCT03841331 |
| Phase 2 | Completed | 3% Minocycline Foam, 0.3% Adapalene Foam | NCT04104685 |
| Phase 2 | Terminated | VYN201 Gel, Vehicle Gel | NCT06493578 |
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