Zenas BioPharma, Inc. (ZBIO) Zenas BioPharma, Inc. functions as a clinical-stage biopharmaceutical firm, concentrating on the creation and market introduction of innovative, immunology-based treatments. The company's primary investigational therapy is obexelimab, a distinctive bifunctional monoclonal antibody intended to address multiple diseases such as immunoglobulin G4-related disease, multiple sclerosis, systemic lupus erythematosus, and warm autoimmune hemolytic anemia. Its developmental portfolio also features ZB002, an anti-TNFa monoclonal antibody; ZB004, a cytotoxic T-lymphocyte-associated antigen 4-immunoglobulin fusion; ZB001, an anti-insulin-like growth factor-1 receptor monoclonal antibody; and ZB005, an anti-active complement component 1s monoclonal antibody. Established in 2019, the entity was formerly recognized as Zenas BioPharma (Cayman) Limited before adopting its current name, Zenas BioPharma, Inc., in August 2023. Its headquarters are located in Waltham, Massachusetts.
Sector: Pharmaceutical Preparations
Industry: Biotechnology
Zenas BioPharma, Inc. NASDAQ:ZBIO Healthcare · Biotechnology
Mkt Cap $1.85B
Vol 0
$ Vol 0
RVOL 0
Earnings 0
Press Release
Zenas BioPharma Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Zenas BioPharma granted 74,900 RSUs to newly hired employees on October 15, 2026, as inducement awards under Nasdaq Listing Rule 5635(c)(4).
The RSUs vest in four equal annual installments through 2030 and are tied to continued service with the company.
This is a routine new-hire equity disclosure with no bearing on the company's clinical programs or financial condition.
• 16d ago AI analysis › Press Release ⚠ 2
Zenas BioPharma Announces the Presentation of New Obexelimab Data in IgG4-Related Disease at the 6th International Symposium on IgG4-Related Disease
Zenas BioPharma presented new Phase 3 INDIGO data on obexelimab in IgG4-related disease at the 6th International Symposium on IgG4-Related Disease.
Open-label extension data showed a 12-month flare-free probability of 0.93 (adjudicated), and a sub-analysis found obexelimab significantly reduced cumulative glucocorticoid toxicity versus placebo at week 52 (GTI difference -11.4; p=0.021).
A vaccine sub-study found 86% influenza and 100% COVID-19 seroimmunity following vaccination during a treatment-free window, with no disease flares observed.
Phase 2 SunStone topline results in systemic lupus erythematosus are expected in 4Q 2026, the next major catalyst for the company.
• 20d ago AI analysis › Press Release
Zenas BioPharma Announces Upcoming Presentations of Orelabrutinib Data in Relapsing Remitting Multiple Sclerosis, Clinical Trial Designs in Progressive Multiple Sclerosis and Other Multiple Sclerosis Portfolio Data at MSToronto2026
Zenas BioPharma will present seven posters on orelabrutinib and obexelimab in multiple sclerosis at the 10th Joint ACTRIMS-ECTRIMS Meeting (MSToronto2026), October 21-23, 2026, in Toronto.
The data include 24-week Phase 2 results for orelabrutinib and obexelimab in relapsing MS, plus designs of the Phase 3 Monarch (non-active SPMS) and PriMroSe (PPMS) trials of orelabrutinib. The company will also host an expert symposium on BTK inhibition in progressive MS.
No new clinical results are disclosed in this release; investors will watch the poster session on October 22 and the SunStone Phase 2 SLE topline expected in 4Q 2026.
• 25d ago AI analysis › Press Release ⚠ 1
Zenas BioPharma to Host Virtual R&D Event
Zenas BioPharma will host a virtual R&D event on Tuesday, October 27, 2026, from 8:00 to 9:30 a.m. ET.
Presentations will cover the pipeline including obexelimab, the company's bifunctional CD19/FcγRIIb antibody in systemic lupus erythematosus, and ZB021, an oral IL-17AA/AF inhibitor, with Dr. Joseph Merola providing clinical insights.
The notice contains no new clinical or financial data; the event may preview obexelimab topline timing in SLE.
• 26d ago AI analysis › Press Release ⚠ 3
Zenas BioPharma Announces Upcoming Presentations of Obexelimab Data in IgG4-Related Disease at the IgG4ward! 6th International Symposium on IgG4-Related Disease and ACR Convergence 2026
Zenas BioPharma (Nasdaq: ZBIO) said new data from the Phase 3 INDIGO trial of obexelimab in IgG4-related disease will be presented at the 6th International Symposium on IgG4-Related Disease (October 8-10, Cambridge, MA) and ACR Convergence 2026 (November 6-11, Orlando, FL).
The lineup includes longer-term flare protection and safety data from the INDIGO open-label extension, plus analyses of glucocorticoid-associated toxicity and of influenza and SARS-CoV-2 vaccine responses in treated patients.
Obexelimab has been evaluated in nine clinical trials totaling 667 subjects; IgG4-RD affects roughly 20,000 diagnosed patients in the US, with true prevalence estimated closer to 40,000.
The release contains no new topline data and mainly reiterates that Phase 2 SunStone topline results in systemic lupus erythematosus are expected in 4Q 2026, the company's next major catalyst.
• 1mo ago AI analysis › Press Release
Zenas BioPharma Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Zenas BioPharma granted inducement equity awards to newly hired employees on September 15, 2026, under Nasdaq Listing Rule 5635(c)(4).
The awards consist of non-qualified stock options to purchase 53,700 shares at an exercise price of $31.93 and 98,900 RSUs, each vesting over four years under the company's 2026 Inducement Plan.
These grants are standard new-hire compensation disclosures and contain no new information on Zenas' clinical pipeline, including its lead candidates obexelimab and orelabrutinib.
• 1mo ago AI analysis › Press Release ⚠ 4
Zenas BioPharma to Host Obexelimab IgG4-RD Investor Event
Zenas BioPharma will host a virtual investor event on obexelimab in IgG4-Related Disease on Tuesday, September 29, 2026, from 8:00 to 9:30 a.m. ET.
Management will be joined by Dr. Guy Katz of Massachusetts General Hospital and plans to cover the IgG4-RD treatment landscape, prelaunch preparedness strategies, and the potential commercial opportunity for obexelimab if approved by the FDA.
The FDA accepted Zenas' Biologics License Application for obexelimab in IgG4-RD in August 2026 with a PDUFA target action date of May 27, 2027, and the company expects to submit a Marketing Authorization Application to the EMA in the second half of 2026.
• 1mo ago AI analysis › Press Release
Zenas BioPharma to Present at Upcoming Healthcare Investor Conferences
Zenas BioPharma announced management presentations at three upcoming healthcare investor conferences: the Citi Biopharma Back to School Conference on September 9, the Morgan Stanley 24th Annual Global Healthcare Conference on September 14, and the H.C. Wainwright 28th Annual Global Investment Conference on September 16, 2026.
Live webcasts and archived replays will be available in the Events and Presentations section of the company website; the release contains no new clinical, financial, or guidance disclosures.
Zenas is a clinical-stage biopharmaceutical company advancing two late-stage candidates, obexelimab and orelabrutinib, for autoimmune and inflammatory diseases, alongside earlier-stage programs ZB021, ZB022, and ZB014.
• 1mo ago AI analysis › Press Release
Zenas BioPharma Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Zenas BioPharma granted an aggregate of 11,000 restricted stock units to newly hired employees as an employment inducement under Nasdaq Listing Rule 5635(c)(4).
The RSUs will vest in four equal annual installments beginning on August 15, 2027, subject to the employees' continued service with the company.
• 2mo ago AI analysis › Press Release ● Major ⚠ 3
Zenas BioPharma Reports Second Quarter 2026 Financial Results and Provides Corporate Update
Zenas BioPharma announced FDA acceptance of the Biologics License Application (BLA) for obexelimab in IgG4-RD, setting a PDUFA target action date of May 27, 2027.
The company reported Q2 revenue of $1.0 million and ended the quarter with $673.9 million in cash and investments, which it estimates will fund operations into Q2 2029.
Phase 3 INDIGO trial data published in the New England Journal of Medicine showed a 56% reduction in flare risk, while the company also announced the appointment of Christy Oliger to its Board of Directors.
• 2mo ago AI analysis › Press Release
Zenas BioPharma Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Zenas BioPharma granted inducement awards to new employees on July 15, 2026, consisting of 35,750 non-qualified stock options and 79,050 restricted stock units.
The stock options have a ten-year term and an exercise price of $29.41 per share, matching the closing price on the grant date.
Both the options and RSUs will vest over a four-year period, with options vesting monthly after the first year and RSUs vesting in equal annual installments beginning in 2027.
• 3mo ago AI analysis › Press Release
Zenas BioPharma Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Zenas BioPharma granted non-qualified stock options and restricted stock units to new employees as an employment inducement on June 15, 2026.
The awards consist of 100,000 stock options with an exercise price of $18.71 and 78,075 RSUs, both subject to four-year vesting schedules.
These grants were made in accordance with Nasdaq Listing Rule 5635(c)(4) and the company’s 2026 Inducement Plan.
• 4mo ago AI analysis › Press Release
Zenas BioPharma to Present at the H.C. Wainwright 7th Annual Neuro Perspectives Expert Summit
Zenas BioPharma will present at the H.C. Wainwright 7th Annual Neuro Perspectives Expert Summit.
The presentation will be available on-demand starting June 15, 2026, at 7:00 a.m. ET.
No new clinical data or regulatory milestones were disclosed in this announcement.
• 4mo ago AI analysis › Press Release ● Critical ⚠ 3
Zenas BioPharma Announces Data from the Registrational Phase 3 INDIGO Trial of Obexelimab in Immunoglobulin G4-Related Disease (IgG4-RD), Simultaneously Presented at the EULAR 2026 Congress and Published in the New England Journal of Medicine
Zenas BioPharma announced positive Phase 3 INDIGO trial data for obexelimab in IgG4-RD, published in the New England Journal of Medicine and presented at EULAR 2026.
The study met its primary endpoint, showing a 56% reduction in flare risk (HR 0.44, p=0.0005) and all four key secondary endpoints, including a 65% reduction in glucocorticoid use and improved safety profile compared to placebo.
A Biologics License Application (BLA) for obexelimab in IgG4-RD was submitted to the FDA in May, positioning the company for a potential regulatory decision on its lead asset.
• 4mo ago AI analysis › Press Release ● Critical ⚠ 3
Zenas BioPharma Announces Submission of Biologics License Application (BLA) to U.S. FDA for Obexelimab in IgG4-RD
Zenas BioPharma submitted a Biologics License Application (BLA) to the FDA for obexelimab, its lead candidate for treating IgG4-Related Disease (IgG4-RD).
The submission is supported by the Phase 3 INDIGO trial, which met its primary endpoint with a 56% reduction in flare risk versus placebo (HR 0.44, p=0.0005) and all four key secondary endpoints.
Data from the INDIGO trial will be presented at the EULAR 2026 Congress on June 4, 2026, marking a critical step toward potential approval and commercialization.
• 5mo ago AI analysis › Press Release ● Major
Zenas BioPharma Announces Upcoming Presentation of Results from Phase 3 INDIGO Registrational Trial of Obexelimab in Immunoglobulin G4-Related Disease (IgG4-RD) at EULAR 2026 Congress
globenewswire.com • 5mo ago Press Release
Zenas BioPharma Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Zenas BioPharma granted 51,075 restricted stock units to newly hired employees as inducement awards under Nasdaq Listing Rule 5635(c)(4).
The RSUs vest in four equal annual installments starting May 15, 2027, contingent on continued service.
This is a routine compliance disclosure for standard employee compensation and does not signal new capital raising or strategic changes.
• 5mo ago AI analysis › Press Release ● Major
Zenas BioPharma Announces First Subject Dosed in Phase 1 Clinical Trial of ZB021, a Novel, Potentially Best-in-Class Oral IL-17AA/AF Inhibitor
globenewswire.com • 5mo ago Press Release ● Major
Zenas BioPharma Reports First Quarter 2026 Financial Results and Provides Corporate Update
globenewswire.com • 5mo ago Press Release ● Major
Zenas BioPharma Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
globenewswire.com • 6mo ago Press Release ● Critical
Zenas BioPharma Announces Pricing of Concurrent Public Offerings of 2.50% Convertible Senior Notes Due 2032 and Common Stock with Aggregate Gross Proceeds of $300.0 Million
globenewswire.com • 7mo ago Press Release ● Critical
Zenas BioPharma Announces Proposed Concurrent Public Offerings of Convertible Senior Notes Due 2032 and Common Stock
globenewswire.com • 7mo ago Press Release ● Major
Zenas BioPharma Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
globenewswire.com • 7mo ago Press Release ● Major
Zenas BioPharma Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Corporate Update
globenewswire.com • 7mo ago Press Release ● Major
Zenas BioPharma Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
globenewswire.com • 8mo ago Press Release ● Major
Zenas BioPharma Announces Late-Breaking Platform Presentation of Results from Phase 2 MoonStone Trial of Obexelimab in Relapsing Multiple Sclerosis at ACTRIMS Forum 2026
globenewswire.com • 8mo ago Press Release
Zenas BioPharma to Present at the Guggenheim Emerging Outlook: Biotech Summit 2026
globenewswire.com • 8mo ago 3 law-firm class-action alerts