Bausch Health Companies Inc. (BHC)
Bausch Health Companies Inc., together with its associated entities, is engaged in the development, manufacturing, and commercialization of a diverse portfolio of pharmaceutical products, medical devices, and over-the-counter remedies. Its primary therapeutic focus areas include ophthalmology, digestive health, and dermatology. The enterprise conducts its operations through five principal divisions: Bausch + Lomb, Salix, International Rx, Ortho Dermatologics, and Diversified Products. The Bausch + Lomb segment is dedicated to vision care, encompassing surgical instruments, consumer eye health products, and ophthalmic pharmaceuticals. Salix specializes in delivering gastroenterology-specific products exclusively within the United States. The International Rx division markets Solta products, a range of branded and generic pharmaceuticals, OTC items, medical devices, and Bausch + Lomb offerings across diverse geographies including Canada, Europe, Asia, Australia, Latin America, Africa, and the Middle East. Ortho Dermatologics focuses on dermatological products in the U.S., in addition to distributing Solta's medical aesthetic devices globally. Finally, the Diversified Products segment supplies pharmaceutical solutions for neurology and other therapeutic categories, as well as generic medications and dental products, all within the U.S. The company was formerly known as Valeant Pharmaceuticals International, Inc., officially changing its name to Bausch Health Companies Inc. in July 2018. Its corporate headquarters are located in Laval, Canada.
Sector: Pharmaceutical Preparations
Industry: Drug Manufacturers - Specialty & Generic
Bausch Health Companies Inc.
Trials need funding. See this company's dilution risk and cash position.
- Phase 4Completed
Canadian Aesthetic Experience With Sculptra Therapy
Poly-L-Lactic Acid
Skin Aging
NCT00447551Enrollment76StartJan 2007Primary CompletionApr 2008CompletionApr 2008 - Phase 4Completed
Safety of Subcutaneous Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness
Methylnaltrexone bromide
Opioid-Induced Constipation
NCT00672139Enrollment156StartJul 2008Primary CompletionJan 2013CompletionMay 2013 - Phase 4Completed
Study Evaluating Subcutaneous Methylnaltrexone For Treatment Of Opioid-Induced Constipation In Patients With Advanced Illness
Methylnaltrexone, Placebo
Opioid-Induced Constipation
NCT00672477Enrollment237StartJun 2008Primary CompletionFeb 2013CompletionFeb 2013 - Phase 4Completed
Evaluation of Irritation That Could be Caused by Two Facial Gels Applied to Opposite Sides of the Face.
Adapalene Gel, Tretinoin Gel
Acne Vulgaris
NCT00714714Enrollment25StartJan 2008Primary CompletionFeb 2008CompletionFeb 2008 - Phase 4Withdrawn
Study Evaluating Safety & Efficacy of Subcutaneous Methylnaltrexone on Opioid-Induced Constipation in Cancer Subjects
methylnaltrexone, placebo
Opioid-Induced Constipation
NCT00858754Enrollment0StartMar 2009Primary CompletionAug 2009CompletionAug 2009 - Phase 4Completed
A Study of Different Use Regimens Using Two Acne Treatments
benzoyl peroxide wash, Tretinoin gel
Acne Vulgaris
NCT00907257Enrollment247StartFeb 2009Primary CompletionSep 2009CompletionSep 2009 - Phase 4Completed
Evaluation of Irritation by Two Facial Gels Applied to Opposite Sides of the Face
Tretinoin gel, Adapalene and Benzoyl peroxide
Acne Vulgaris
NCT00919191Enrollment26StartApr 2009Primary CompletionMay 2009CompletionMay 2009 - Phase 4Completed
Evaluation of Irritation That Potentially Could be Caused by Two Facial Gels Applied to Opposite Sides of the Face
Tretinoin Facial Gel, Adapalene/Benzoyl Peroxide Facial Gel
Acne Vulgaris
NCT00952523Enrollment162StartJul 2009Primary CompletionOct 2009CompletionOct 2009 - Phase 4Completed
Study Evaluating Two Dose Levels of Targretin Capsules in Participants With Refractory Cutaneous T-Cell Lymphoma (CTCL)
Bexarotene
Refractory Cutaneous T-cell Lymphoma
NCT01007448Enrollment59StartJan 2010Primary CompletionFeb 2014CompletionFeb 2014 - Phase 4Completed
A Study That Evaluates the Decrease in Irritation When Using Additional Acne Treatment Products
Dapsone plus Tretinoin Gel, Tretinoin Gel
Acne Vulgaris
NCT01313728Enrollment26StartDec 2010Primary CompletionDec 2010CompletionJan 2011 - Phase 4Completed
Safety and Efficacy of OsmoPrep® Tablets Versus HalfLytely® and Bisacodyl Tablet Bowel Prep Kit for Colon Cleansing
Polyethylene glycol, Oral sodium phosphate solution
Colon Cleansing
NCT01427296Enrollment2,154StartSep 2011Primary CompletionMar 2014CompletionDec 2014 - Phase 4Completed
The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy
Rifaximin, Lactulose
Hepatic Encephalopathy, Cirrhosis
NCT01842581Enrollment222StartJan 2013Primary CompletionDec 2014CompletionDec 2014 - Phase 4Terminated
Efficacy, Safety, And Pharmacokinetics Of Rifaximin In Subjects With Severe Hepatic Impairment And Hepatic Encephalopathy
Placebo, Rifaximin
Hepatic Encephalopathy
NCT01846663Enrollment6StartApr 2013Primary CompletionFeb 2016CompletionFeb 2016 - Phase 4Not yet recruiting
Efficacy and Safety of Bupropion Hydrobromide in Adolescents and Children With Major Depressive Disorder
bupropion hydrobromide, Placebo
Major Depressive Disorder
NCT02129751Enrollment246StartJul 2027est.Primary CompletionJul 2030est.CompletionDec 2030est. - Phase 4Completed
Maximal Use of Luliconazole Cream 1% in Pediatric Participants With Moderate to Severe Tinea Pedis or Tinea Cruris
Luliconazole Cream 1%
Tinea Pedis, Tinea Cruris
NCT02767271Enrollment30StartDec 2015Primary CompletionApr 2016CompletionApr 2016 - Phase 4Completed
Safety and Efficacy of Product 33525 (Luliconazole Cream 1%) in Pediatric Participants With Tinea Corporis
Luliconazole Cream 1%, Vehicle Cream
Tinea Corporis
NCT02767947Enrollment75StartFeb 2016Primary CompletionJun 2016CompletionSep 2016 - Phase 4Completed
Safety and Pharmacokinetics of Efinaconazole Topical Solution in Subjects With Mild to Severe Onychomycosis
Efinaconazole
Onychomycosis
NCT02812771Enrollment62StartAug 2016Primary CompletionJan 2019CompletionJan 2019 - Phase 4Active, not recruiting
An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects
Brodalumab, Brodalumab
Psoriasis
NCT03240809Enrollment2StartJan 2020Primary CompletionDec 2028est.CompletionJun 2029est. - Phase 4Terminated
Steady-State Pharmacokinetics of Rifaximin 550 mg Tablets in Healthy and Hepatically Impaired Subjects
Rifaximin
Severe Hepatic Impairment
NCT03818672Enrollment5StartJan 2019Primary CompletionFeb 2020CompletionFeb 2020 - Phase 4Active, not recruiting
A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis
IDP-122 Lotion
Psoriasis
NCT03987763Enrollment45StartOct 2019Primary CompletionNov 2026est.CompletionApr 2027est. - Phase 4Completed
A Safety and Pharmacokinetics Study of IDP-118 Lotion in Pediatric Participants With Plaque Psoriasis
IDP-118 Lotion
Psoriasis
NCT03988439Enrollment16StartMar 2021Primary CompletionFeb 2026CompletionFeb 2026 - Phase 4Recruiting
Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis
Low Dose Budesonide, High Dose Budesonide
Ulcerative Colitis
NCT04314375Enrollment70StartSep 2023Primary CompletionDec 2026est.CompletionJun 2027est. - Phase 4Not yet recruiting
Dose Ranging Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Rectal Foam in Pediatric Patients Aged 5 to 17 Years With Active, Mild to Moderate Distal Ulcerative Colitis
High dose budesonide rectal foam, Low dose budesonide rectal foam
Ulcerative Colitis
NCT05976802Enrollment100StartJun 2029est.Primary CompletionJun 2030est.CompletionJan 2031est. - Phase 4Recruiting
Rifaximin 200 mg Plus Oral Rehydration vs Oral Rehydration Alone in Children With Acute Diarrhea
Rifaximin 200 mg Tablet
Diarrhea, Gastroenteritis +2
NCT07285785Enrollment54StartFeb 2026Primary CompletionApr 2027est.CompletionJul 2027est. - Phase 4Recruiting
Study to Assess Safety, Pharmacokinetics, and Treatment Effect of Cabtreo
CABTREO is a fixed-combination product of clindamycin phosphate 1.2%/BPO 3.1%/adapalene 0.15%.
Acne Vulgaris
NCT07524946Enrollment100StartApr 2026Primary CompletionDec 2027est.CompletionDec 2027est.
| Drug / Therapy | Link | ||
|---|---|---|---|
| Phase 4 | Completed | Poly-L-Lactic Acid | NCT00447551 |
| Phase 4 | Completed | Methylnaltrexone bromide | NCT00672139 |
| Phase 4 | Completed | Methylnaltrexone, Placebo | NCT00672477 |
| Phase 4 | Completed | Adapalene Gel, Tretinoin Gel | NCT00714714 |
| Phase 4 | Withdrawn | methylnaltrexone, placebo | NCT00858754 |
| Phase 4 | Completed | benzoyl peroxide wash, Tretinoin gel | NCT00907257 |
| Phase 4 | Completed | Tretinoin gel, Adapalene and Benzoyl peroxide | NCT00919191 |
| Phase 4 | Completed | Tretinoin Facial Gel, Adapalene/Benzoyl Peroxide Facial Gel | NCT00952523 |
| Phase 4 | Completed | Bexarotene | NCT01007448 |
| Phase 4 | Completed | Dapsone plus Tretinoin Gel, Tretinoin Gel | NCT01313728 |
| Phase 4 | Completed | Polyethylene glycol, Oral sodium phosphate solution | NCT01427296 |
| Phase 4 | Completed | Rifaximin, Lactulose | NCT01842581 |
| Phase 4 | Terminated | Placebo, Rifaximin | NCT01846663 |
| Phase 4 | Not yet recruiting | bupropion hydrobromide, Placebo | NCT02129751 |
| Phase 4 | Completed | Luliconazole Cream 1% | NCT02767271 |
| Phase 4 | Completed | Luliconazole Cream 1%, Vehicle Cream | NCT02767947 |
| Phase 4 | Completed | Efinaconazole | NCT02812771 |
| Phase 4 | Active, not recruiting | Brodalumab, Brodalumab | NCT03240809 |
| Phase 4 | Terminated | Rifaximin | NCT03818672 |
| Phase 4 | Active, not recruiting | IDP-122 Lotion | NCT03987763 |
| Phase 4 | Completed | IDP-118 Lotion | NCT03988439 |
| Phase 4 | Recruiting | Low Dose Budesonide, High Dose Budesonide | NCT04314375 |
| Phase 4 | Not yet recruiting | High dose budesonide rectal foam, Low dose budesonide rectal foam | NCT05976802 |
| Phase 4 | Recruiting | Rifaximin 200 mg Tablet | NCT07285785 |
| Phase 4 | Recruiting | CABTREO is a fixed-combination product of clindamycin phosphate 1.2%/BPO 3.1%/adapalene 0.15%. | NCT07524946 |
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