Lineage Cell Therapeutics, Inc. (LCTX) Lineage Cell Therapeutics, Inc., a clinical-stage biotechnology company, developing cell replacement therapies to treat serious medical conditions in the United States and internationally. The company develops OpRegen, an allogeneic retinal pigment epithelium cell replacement therapy, which is in Phase 2a clinical trial for the treatment of the age-related macular degeneration; and OPC1, an allogeneic oligodendrocyte progenitor cell therapy that is in Phase 1/2a multicenter clinical trial for the treatment of cervical spinal cord injuries. It also offers ReSonance (ANP1), an allogeneic auditory neuron progenitor cell transplant, which is in preclinical development for the treatment of sensorineural hearing loss; and PNC1, an allogeneic photoreceptor cell transplant, which is in preclinical development for the treatment of vision loss due to photoreceptor dysfunction or damage. In addition, the company is developing RND1, a novel hypoimmune induced pluripotent stem cell line for the development of a cell transplant candidate for the potential treatment of an undisclosed indication, as well as engages in the research and development of ILT1, an allogeneic cell transplant for the treatment of Type 1 Diabetes; and LCT-CON, an allogeneic cell transplant, as well as therapeutic products for retinal diseases, neurological diseases, ophthalmology, metabolic, and disorders and oncology. The company has a collaboration agreement with William Demant Invest for the preclinical development of ReSonance (ANP1). It also has a strategic collaboration with Factor Bioscience Inc. for the development of genetically engineered iPSC line for the company to utilize for differentiation into certain cell transplant product candidates. The company was formerly known as BioTime, Inc. and changed its name to Lineage Cell Therapeutics, Inc. in August 2019. Lineage Cell Therapeutics, Inc. was incorporated in 1990 and is headquartered in Carlsbad, California.
Sector: Biological Products, (No Diagnostic Substances)
Industry: Biotechnology
Lineage Cell Therapeutics, Inc. NYSE:LCTX Healthcare · Biotechnology
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Lineage Cell Therapeutics (NYSEAMERICAN:LCTX) Shares Climb 8.7% – Here’s What Happened
defenseworld.net • 28d ago Press Release ⚠ 3
Lineage Cell Therapeutics Announces Issuance of Patent Underlying Its AlloSCOPE™ 5D Manufacturing Platform
Lineage Cell Therapeutics said the USPTO has issued U.S. Patent No. 12,692,476 with claims covering its proprietary AlloSCOPE cell manufacturing platform, including the AlloSCOPE 5D technology, with an expected expiration date of June 9, 2043.
The 5D method merges 2D-like growth control with 3D bioreactor scale, and management believes it can support commercial-scale production of high-dose cell therapies requiring as many as a billion cells per patient, such as potential islet-cell treatments for Type 1 Diabetes.
Lineage has already deployed AlloSCOPE 5D to support its COR1 corneal endothelial program and plans to apply it to the ILT1 manufacturing initiative; CEO Brian Culley called the patent a critical asset addressing two major commercialization obstacles for pluripotent cell-derived therapies.
• 1mo ago AI analysis › News
Lineage Cell Therapeutics Q2 Earnings Call Highlights
marketbeat.com • 2mo ago News
Lineage Cell Therapeutics, Inc. (LCTX) Q2 2026 Earnings Call Transcript
seekingalpha.com • 2mo ago News
Lineage Cell (LCTX) Reports Q2 Loss, Lags Revenue Estimates
zacks.com • 2mo ago SEC Filing ⚠ 6
LCTX: 10-Q · periodic report
Lineage Cell Therapeutics (LCTX) reported Q2 2026 revenue of $1.1 million, down 61% year over year, alongside a quarterly net income of $1.5 million that was driven almost entirely by an $11.8 million non-cash gain from the falling fair value of its warrant liabilities rather than operations. The first-half net loss attributable to Lineage narrowed to $3.3 million from $34.6 million a year ago.
The company ended June 30, 2026 with $50.8 million in cash, cash equivalents and marketable securities and said this funds planned operations for at least twelve months. Operating cash burn rose to $15.3 million for the first half from $10.4 million a year earlier, partially offset by $5.4 million of warrant exercises and $4.6 million of ATM share sales at a $1.28 weighted average price.
Pipeline momentum continues under the Roche/Genentech collaboration: the Phase 2a GAlette study of OpRegen is active at 17 sites, and 36-month Phase 1/2a data showed a mean +9.0 letter best-corrected visual acuity gain in the five patients with extensive retinal coverage. OPC1 advanced in the DOSED spinal cord injury study at UC San Diego Health, and the WDI-funded ReSonance program has received roughly $2.6 million of up to $12 million in collaboration funding.
Watch items include an Israeli court granting HBL's books-and-records motion in March 2026 after a third-party valuation firm found the consideration paid by Lineage to CCN under their intercompany agreement insufficient, opening the door to a potential derivative action. The 2026 Iran War also raises operational risk at the company's concentrated Jerusalem manufacturing base, though Lineage reports no material disruption to date.
SEC 10-Q • 2mo ago AI analysis › Press Release ● Major ⚠ 2
Lineage Cell Therapeutics Reports Second Quarter 2026 Financial Results and Provides Business Update
Lineage Cell Therapeutics reported Q2 2026 revenue of $1.1 million, down from $2.8 million in the prior year, primarily due to deferred collaboration revenue from Roche/Genentech. The company posted net income of $1.5 million, or $0.01 per share, driven by a fair value remeasurement of warrant liabilities and the absence of a prior-year impairment charge.
Operationally, the company highlighted positive 3-year Phase 1/2a data for its OpRegen cell therapy, showing sustained vision gains in geographic atrophy patients. Additionally, Lineage advanced its new COR1 program for corneal disease into in-vivo testing, leveraging its proprietary AlloSCOPE 5D manufacturing platform.
The balance sheet remains robust with $50.8 million in cash and marketable securities, sufficient to fund planned operations into the third quarter of 2028.
• 2mo ago AI analysis › Press Release
Lineage Cell Therapeutics to Report Second Quarter 2026 Financial Results and Provide Business Update on August 6, 2026
Lineage Cell Therapeutics announced it will report its second quarter 2026 financial results on August 6, 2026, after the market closes.
Management will host a conference call and webcast at 4:30 p.m. ET to discuss the results and provide a business update.
The company is a clinical-stage biotechnology firm focused on allogeneic cell therapies for serious medical conditions.
• 2mo ago AI analysis › News
Lineage Cell Therapeutics Maps COR1 Path With ‘Thaw and Inject' Cell Therapy Plan
marketbeat.com • 3mo ago News
Lineage Cell Therapeutics, Inc. (LCTX) Discusses COR1 Cell Transplant Program and Manufacturing Strategy for Corneal Endothelial Disease Transcript
seekingalpha.com • 3mo ago Press Release
Lineage Provides Update on COR1 Cell Therapy Program for Corneal Endothelial Disease
Lineage Cell Therapeutics advanced its preclinical COR1 program into in-vivo animal testing for corneal endothelial disease, aiming to address donor shortages.
The company successfully utilized its proprietary AlloSCOPE platform to meet manufacturing thresholds for potency and scale, targeting a "thaw-and-inject" formulation to improve upon cadaver-derived cells.
Management expects initial data from the animal studies to be generated this year.
• 3mo ago AI analysis › Press Release
Lineage Cell Therapeutics to Present at B. Riley Securities 2026 Mind, Muscle & Vision Healthcare Summit
Lineage Cell Therapeutics announced that CEO Brian M. Culley will present at the B. Riley Securities 2026 Mind, Muscle & Vision Healthcare Summit.
The fireside chat, hosted by B. Riley analyst Mayank Mamtani, is scheduled for July 16, 2026, at the InterContinental Boston.
Investors interested in scheduling one-on-one meetings with the management team are encouraged to contact their B. Riley representative.
• 3mo ago AI analysis › SEC Filing
LCTX: 8-K · proxy statement
Lineage Cell Therapeutics reported the results of its annual shareholder meeting held on June 10, 2026. Shareholders elected all seven director nominees and ratified the appointment of Baker Tilly US, LLP as the independent auditor for the fiscal year ending December 31, 2026.
Shareholders also approved the executive compensation advisory vote (say-on-pay) with approximately 97% of votes cast in favor. The filing also disclosed that the company withdrew its application for a Clinical Trial award from the California Institute for Regenerative Medicine (CIRM) on June 9, 2026.
The company stated that the withdrawal of the CIRM grant application does not impact the ongoing DOSED clinical study for its OPC1 therapy in spinal cord injury patients. This routine governance filing confirms board stability and continued clinical development without significant financial or operational disruption.
SEC 8-K • 4mo ago News
Lineage Cell Therapeutics Q1 Earnings Call Highlights
marketbeat.com • 5mo ago News
Lineage Cell Therapeutics, Inc. (LCTX) Q1 2026 Earnings Call Transcript
seekingalpha.com • 5mo ago News
Lineage Cell (LCTX) Reports Q1 Loss, Lags Revenue Estimates
zacks.com • 5mo ago SEC Filing ⚠ 1
LCTX: 10-Q · periodic report
Lineage Cell Therapeutics, Inc. reported a net loss of $4.812 million for the three months ended March 31, 2026, compared to a net loss of $4.139 million for the same period in 2025. The company's total revenue increased by 15% to $1.725 million in the first quarter of 2026, driven by a $0.3 million increase in collaboration revenues from the WDI collaboration. The company's cash position as of March 31, 2026, was $35.939 million, down from $40.791 million at the end of 2025. The decrease in cash is primarily due to the net cash used in operating activities, which was $8.078 million for the quarter. Despite the net loss, the company believes its current cash, cash equivalents, and marketable securities will be sufficient to fund operations for at least the next twelve months. The company's pipeline includes several cell therapy programs, with OpRegen in Phase 2a development for the treatment of geographic atrophy secondary to dry-AMD, and ReSonance in preclinical development for auditory neuropathy. The company also announced the launch of the COR1 program for corneal endothelial disease, and the ILT1 initiative for islet cell manufacturing. The ongoing Israeli regional conflict and broader geopolitical tensions pose a risk to the company's operations, particularly given the significant presence of its workforce and manufacturing facilities in Jerusalem. However, as of the filing date, the company has not experienced any material disruptions.
SEC 10-Q • 5mo ago AI analysis › SEC Filing
LCTX: 8-K · earnings release
On May 12, 2026, Lineage Cell Therapeutics, Inc. reported financial results for the quarter ended March 31, 2026. The company generated total revenues of approximately $1.7 million, a net increase of $0.2 million compared to the same period in 2025, primarily driven by collaboration revenue from a new research agreement with William Demant Invest A/S (WDI).
The company's operating expenses increased to $9.3 million for the quarter, up $1.3 million from the same period in 2025. This increase was mainly due to higher R&D expenses, which rose by $1.1 million to $4.2 million, and G&A expenses, which increased by $0.2 million to $5.1 million.
Lineage also announced several operational highlights, including the launch of a new corneal endothelial disease cell therapy program (COR1) and the successful treatment of a second chronic SCI patient in the DOSED study using a novel delivery system. The company's cash position of $53.4 million as of March 31, 2026, is expected to support planned operations into Q2 2028.
The company established a Scientific Advisory Board, with Joachim Fruebis, PhD, as its founding member, and appointed Priyantha Herath, MD, PhD, as Senior Vice President & Head of Clinical. These appointments are expected to provide strategic counsel and enhance the company's clinical development capabilities.
SEC 8-K • 5mo ago AI analysis › Press Release ● Major
Lineage Cell Therapeutics Reports First Quarter 2026 Financial Results and Provides Business Update
businesswire.com • 5mo ago Press Release
Lineage Cell Therapeutics to Report First Quarter 2026 Financial Results and Provide Business Update on May 12, 2026
Lineage Cell Therapeutics scheduled the release of its first quarter 2026 financial results for after the market close on May 12, 2026.
Management will conduct a conference call and webcast at 4:30 p.m. Eastern Time to review the quarterly results and provide a business update.
The company is a clinical-stage biotechnology firm developing allogeneic cell therapies, including programs for macular degeneration and spinal cord injuries.
• 5mo ago AI analysis › Press Release
OpRegen® 3 Year Results in Patients With GA Presented at Foundation Fighting Blindness Retinal Innovation Summit 2026
businesswire.com • 5mo ago Press Release
Lineage Announces Formation of Scientific Advisory Board
businesswire.com • 6mo ago