MILESTONE SCIENTIFIC INC. (MLSS) Milestone Scientific Inc. is dedicated to the innovation, refinement, and global distribution of advanced diagnostic and therapeutic injection technologies and devices. These solutions cater to the medical, dental, and cosmetic industries, with a presence in the United States, China, and other international markets. The company's operations are divided into two main segments: Dental and Medical. Within its Dental division, key products include CompuDent and the STA Single Tooth Anesthesia System, both instrumental for delivering local anesthetics across all dental procedures. For broader applications, the firm offers CompuFlo, a sophisticated computer-controlled system capable of delivering drugs, anesthetics, and other medicaments comfortably and precisely, as well as aspirating bodily fluids or prior injections. Complementing this, a disposable injection handpiece provides precise tactile control during administration. In the Medical segment, Milestone Scientific introduces the CompuFlo Epidural, a computer-guided anesthesia system designed for a variety of medical applications. Additionally, their CompuMed system is utilized in numerous specialized procedures, including plastic surgery, hair restoration, colorectal surgery, podiatry, dermatology, and orthopedics, among others. Headquartered in Livingston, New Jersey, Milestone Scientific Inc. was established in 1989.
Sector: Orthopedic, Prosthetic & Surgical Appliances & Supplies
Industry: Medical - Instruments & Supplies
Milestone Scientific Inc. NYSE:MLSS Healthcare · Medical - Instruments & Supplies
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Critical Survey: TerrAscend (OTCMKTS:TSNDF) versus Milestone Scientific (NYSE:MLSS)
defenseworld.net • 14d ago Press Release ⚠ 3
Milestone Scientific Highlights Building a Scalable Growth Platform for CompuFlo® Medical Business
Milestone Scientific highlighted progress building a scalable growth platform for its CompuFlo medical business, centered on physician adoption, reimbursement and recurring disposable revenue.
Through September 2026 the CompuFlo Advisor Program generated over 180 epidural feedback submissions, building on a 145-procedure evaluation in which 99.3% of respondents found the technology easy to use; providers currently receive approximately $325 per procedure in Medicare payment under CPT 0777T in Novitas and First Coast jurisdictions.
Clinical evidence continues to accumulate, including a 79-patient UTMB study associating CompuFlo-guided epidural access with roughly a 91% reduction in adjusted odds of composite complications.
The company has also expanded its commercial organization to three dedicated sales professionals, about 15 consultants and three distribution partners, with international market development underway in Italy, Chile and Qatar and a long-term goal of moving CPT 0777T from Category III to Category I.
• 27d ago AI analysis › SEC Filing ⚠ 2
MLSS: S-3/A · shelf registration
Milestone Scientific filed Pre-Effective Amendment No. 1 to its Form S-3 shelf registration on September 18, 2026, solely to correct a clerical error: the original filing's signature page inadvertently omitted the company's signature block.
The underlying shelf registration (File No. 333-298804), originally filed September 8, 2026, covers up to an aggregate offering price of $45,000,000 of common stock, preferred stock, warrants, rights, and units, to be sold from time to time on a delayed or continuous basis under Rule 415.
The amendment also attaches a conformed Exhibit 5.1 legal opinion from Tarter Krinsky & Drogin LLP and does not modify the prospectus or any other Part II information. No securities have been priced or sold under the shelf; the meaningful dilution signal will come from any future prospectus supplement, not this housekeeping amendment.
SEC S-3/A • 1mo ago AI analysis › Press Release ⚠ 2
Milestone Scientific Announces Pain and Spine Specialists and Dr. Sudhir Rao as CompuFlo® Development Partner and Advisor
Milestone Scientific added Pain and Spine Specialists and its Medical Director Dr. Sudhir Rao as a development partner and member of the CompuFlo Advisor Program.
The partner is a multi-state interventional pain management organization with 22 locations across Maryland, Pennsylvania, Virginia and Florida, a footprint that overlaps two Medicare Administrative Contractor regions (Jurisdiction L via Novitas and Jurisdiction N via First Coast) that Milestone views as strategically important.
The collaboration provides real-world clinical feedback on CompuFlo's objective epidural confirmation and supports Milestone's longer-term push for Category I CPT status, though no financial terms or volume commitments were disclosed.
• 1mo ago AI analysis › SEC Filing ⚠ 5
MLSS: S-3 · shelf registration
Milestone Scientific filed a Form S-3 universal shelf registration on September 8, 2026, registering up to $45,000,000 of securities — common stock, preferred stock, warrants, subscription rights, and units — for sale from time to time in one or more offerings.
Most of the capacity is carry-forward: $41,763,620 of unsold securities from the company's prior shelf (File No. 333-275088, effective October 30, 2023), with only $3,236,380 newly registered. The $446.94 filing fee was fully offset by fees paid on the prior registration, so the net fee due is $0.
Proceeds are earmarked for working capital and general corporate purposes, with management retaining broad discretion over allocation. Context is significant: the filing repeats going-concern language, notes MLSS closed at $0.46 per share on September 2, 2026, and flags the risk of failing to regain or maintain compliance with NYSE American listing requirements.
No securities are being sold at this time. Any future takedown would dilute the 90,644,403 shares outstanding as of September 8, 2026, and the risk factors explicitly warn that actual or perceived sales under the shelf could materially dilute stockholders and pressure the stock price.
SEC S-3 • 1mo ago AI analysis › Press Release
Milestone Scientific Achieves Debt-Free Balance Sheet Through Debt-to-Equity Conversion by Three Directors
Three members of Milestone Scientific's Board of Directors converted $465,000 of outstanding loans into common stock, eliminating the company's remaining debt and achieving a debt-free balance sheet.
The conversion was effective August 19, 2026, at a price of $0.50 per share, representing a 6.4% premium to the prior closing price of $0.47.
The transaction resulted in the issuance of 976,870 shares of common stock to the directors, with CEO Eric Hines highlighting the move as a step that strengthens the financial position and aligns leadership interests with shareholders.
• 2mo ago AI analysis › News
Milestone Scientific Inc. (MLSS) Q2 2026 Earnings Call Transcript
seekingalpha.com • 2mo ago Press Release ⚠ 3
Milestone Scientific Reports Financial Results for Second Quarter 2026
Milestone Scientific reported Q2 revenue of $2.8 million, up 22% year-over-year, while narrowing its net loss to $1.1 million from $1.5 million in the prior year period.
The medical segment drove growth with CompuFlo revenue increasing 230% YoY, supported by a new strategic distribution agreement with Red One Medical to supply the VA and Department of Defense.
Management reaffirmed its 2026 outlook for double-digit revenue growth to $9.8-$10.2 million and targets cash flow breakeven by early 2027.
• 2mo ago AI analysis › SEC Filing ● Major ⚠ 7
MLSS: 10-Q · periodic report
Milestone Scientific's Q2 2026 revenue rose 22.3% year over year to $2.84 million, powered by roughly $498,000 of renewed China sales and 231.5% growth in Medical segment revenue, while the quarterly net loss narrowed to $1.06 million from $1.48 million.
The 10-Q nonetheless retains substantial doubt about the company's ability to continue as a going concern, citing a $135.7 million accumulated deficit and the need for additional financing. The April 2026 private placement ($2.15 million gross at $0.27 per unit plus three-year warrants at $0.3375) lifted cash to $2.1 million and cut six-month operating cash burn to $498,000 from $2.77 million a year earlier.
The key overhang is listing risk: stockholders' equity of about $3.5 million remains below NYSE American's $4 million minimum, and the company must regain compliance by April 8, 2027 or face delisting procedures. Warrants plus roughly $449,000 of convertible notes add meaningful further dilution on top of the ~10% share increase from the private placement.
SEC 10-Q • 2mo ago AI analysis › Press Release
Milestone Scientific Schedules Second Quarter 2026 Financial Results Conference Call
Milestone Scientific announced it will host a conference call on August 14, 2026, to discuss its second quarter 2026 financial results and corporate progress.
The company specializes in computerized drug delivery instruments for medical and dental applications, utilizing its proprietary DPS Dynamic Pressure Sensing Technology.
Investors can access the live call starting at 8:30 AM Eastern Time via telephone or webcast, with a replay available until August 28.
• 2mo ago AI analysis › Press Release ⚠ 1
Milestone Scientific Announces Strategic Federal Distribution Partnership with Red One Medical to Expand Commercial Access for the CompuFlo® Epidural System
Milestone Scientific entered a strategic distribution agreement with Red One Medical to commercialize its CompuFlo Epidural System within federal healthcare channels including the VA and Department of Defense.
The partnership targets a massive patient base of over 18 million veterans and military beneficiaries across 170 medical centers and 1,200 outpatient sites.
Management believes this creates a pathway for long-term revenue growth, though the agreement does not guarantee specific contract awards or purchase orders.
• 2mo ago AI analysis › SEC Filing ⚠ 2
MLSS: 8-K · proxy statement
Milestone Scientific Inc. reported the results of its 2026 Annual Meeting held on July 27, 2026, where stockholders elected five incumbent directors and approved proposals to increase authorized shares and amend the equity incentive plan. All proposals passed, including the ratification of Grassi & Co. Certified Public Accountants, PC as the independent auditor for the fiscal year ending December 31, 2026.
Subsequent to the mailing of the proxy materials, the Board elected Kelly Ulto and Greg Shilling as directors to fill vacancies and serve on key committees. The Board subsequently re-elected them to serve until the 2027 Annual Meeting, reaffirming their independence and appointing Ms. Ulto as Chair of the Audit Committee and Mr. Shilling as Chair of the Compensation Committee.
SEC 8-K • 2mo ago AI analysis › SEC Filing ⚠ 2
MLSS: 8-K · other
Milestone Scientific Inc. disclosed that three directors have submitted notices to convert their remaining principal holdings in the company's Convertible Bridge Notes into common stock. The notices were received from Benedetta Casamento, Dr. Didier Demesmin, and Neal Goldman, covering a combined principal balance of approximately $466,000 plus accrued interest.
The conversions will take effect automatically once the fair value of the common stock reaches at least $0.50 per share and the directors comply with insider trading policies. No shares have been issued yet, and the original notes were issued for an aggregate principal amount of $800,000 prior to a partial conversion in April 2026.
SEC 8-K • 2mo ago Press Release
Milestone Scientific Launches First Phase of AI Strategy with Pilot Debut of Milo, an AI-enabled Digital Engagement Platform, at ASPN 2026
Milestone Scientific debuted 'Milo,' an AI-enabled digital engagement platform, as a pilot at the ASPN 2026 conference to enhance customer support and commercial execution.
The platform is designed to answer product questions, qualify leads, and schedule demonstrations for healthcare professionals, serving as the first phase of the company's broader AI strategy.
Management plans to use feedback from the pilot to guide future development, with a focus on integrating AI across commercial, clinical, and customer support activities.
• 3mo ago AI analysis › Press Release
Milestone Scientific Reports Preliminary 1H 2026 Revenue of ~$5.0M, +9% YoY; Q2 2026 Revenue of ~$2.8M, +21% YoY
Milestone Scientific reported preliminary Q2 2026 revenue of approximately $2.8 million, a 21% increase from $2.3 million in the prior year, with first-half revenue reaching $5.0 million.
The medical segment drove significant momentum with 300% year-over-year growth, supplemented by $500,000 in upside from international orders.
Management highlighted progress on reimbursement claims and plans to showcase technology at the ASPN Conference in mid-July.
• 3mo ago AI analysis › Press Release
Milestone Scientific Strengthens Board to Support Next Phase of Growth
Milestone Scientific appointed Greg Shilling and Kelly Ann Ulto as independent directors, while Benedetta I. Casamento transitioned from Chair of the Board to Executive Chair to strengthen governance and support growth.
Shilling brings over 30 years of healthcare technology and software experience, while Ulto adds deep expertise in audit and financial controls, having trained SEC and FINRA examiners.
The company also restructured its agreement with founder Leonard Osser, who moves to an advisory role, to align shareholder interests and provide greater operational flexibility.
• 4mo ago AI analysis › SEC Filing ⚠ 4
MLSS: DEF 14A · proxy statement
Milestone Scientific filed its definitive proxy statement for the 2026 annual meeting, requesting stockholder approval for five proposals. Key proposals include the election of five directors, an increase in authorized common stock from 125 million to 135 million shares, and an increase in the share reserve of the 2020 Equity Incentive Plan from 11.5 million to 28.75 million shares.
The expansion of the equity plan is intended to cover the settlement of 11.2 million performance-based restricted stock units (PRSUs) recently granted to senior executives, including CEO Eric Hines. The company noted that the new shares represent an 11.31% basic dilution and are necessary to support retention and performance incentives without increasing cash compensation.
The proxy also discloses a repricing of underwater stock options for the CEO and Senior VP of Sales in April 2026, reducing the exercise price to $0.31 per share. Additionally, the company seeks ratification for a new independent auditor, Grassi & Co., following the departure of CBIZ CPAs, and details significant related party transactions with supplier United Systems.
SEC DEF 14A • 4mo ago SEC Filing ⚠ 5
MLSS: 424B1 · prospectus supplement
Milestone Scientific Inc. filed a prospectus supplement to register the resale of 15,925,926 shares of common stock by selling stockholders, representing a significant overhang of approximately 18% of the company's 88.4 million outstanding shares. The registered shares include 7.96 million shares issued in a private placement on April 20, 2026, and an equal number of shares underlying warrants issued in the same transaction.
The company will not receive any proceeds from the resale of these shares, which may be sold at market prices, though it could receive up to $2.69 million if all warrants are exercised. The underlying private placement raised $2.15 million at $0.27 per unit, which was critical for increasing stockholders' equity to $4.1 million and addressing a NYSE American delisting notice related to insufficient equity.
Selling stockholders include CEO Eric Hines, Chairman Benedetta Casamento, and directors Neal Goldman and Dr. Didier Demesmin, among others. The filing reiterates that the company is a smaller reporting company with a history of operating losses and has previously expressed substantial doubt about its ability to continue as a going concern.
SEC 424B1 • 4mo ago AI analysis › SEC Filing ⚠ 5
MLSS: S-3 · shelf registration
Milestone Scientific Inc. (MLSS) filed a Form S-3 shelf registration statement to register the resale of 15,925,926 shares of common stock by selling stockholders. These shares consist of 7,962,963 shares issued in a private placement on April 20, 2026, and an equal number of shares issuable upon the exercise of warrants held by those investors.
The private placement raised $2.15 million in gross proceeds, with a unit price of $0.27 and a warrant exercise price of $0.3375. The company stated it will not receive proceeds from the resale of these shares but may receive up to $2.69 million if the warrants are fully exercised.
The filing highlights significant financial distress, noting that management has concluded there is substantial doubt about the company's ability to continue as a going concern. Additionally, the company is non-compliant with NYSE American listing standards regarding stockholders' equity and faces potential delisting if it fails to regain compliance by April 8, 2027.
SEC S-3 • 4mo ago AI analysis › Press Release
Milestone Scientific Highlights Growing Clinical Adoption and Expanding Physician Acceptance of CompuFlo® Across Epidural, Neuromodulation, and Interventional Pain Procedures
Milestone Scientific highlighted growing clinical adoption of its CompuFlo Epidural System following a new peer-reviewed study from the University of Texas Medical Branch.
The study, published in Operative Neurosurgery, found that CompuFlo-guided epidural access during spinal cord stimulator implantation was associated with a 91% reduction in the odds of composite complications compared to conventional techniques.
CEO Eric Hines noted that the technology has been evaluated or utilized across more than 40 universities and academic medical centers worldwide, signaling expanding physician acceptance for procedures including epidural steroid injections and obstetric epidurals.
• 4mo ago AI analysis › News
Milestone Scientific Inc. (MLSS) Q1 2026 Earnings Call Transcript
seekingalpha.com • 5mo ago Press Release ⚠ 2
Milestone Scientific Reports Financial Results for First Quarter 2026
Milestone Scientific reported Q1 2026 revenue of $2.16 million, a 3% decrease from the prior year, but maintained a relatively stable revenue base despite shipping challenges to the Middle East.
The company significantly reduced its operating loss to $828,000, an improvement of $1.2 million from the $2.0 million loss in Q1 2025, driven by a 30% reduction in operating expenses.
Management reaffirmed its outlook for 2026, expecting double-digit revenue growth of $9.8 million to $10.2 million, driven by expanding commercial adoption in both dental and medical segments.
However, the company's 2025 financial statements included an audit report emphasizing substantial doubt about its ability to continue as a going concern, which remains a significant risk despite recent cost reductions and a $2.15 million capital raise in April 2026.
• 5mo ago AI analysis › SEC Filing ⚠ 4
MLSS: 10-Q · periodic report
Milestone Scientific Inc. reported a net loss of $839,853 for the three months ended March 31, 2026, compared to a net loss of $1,994,586 for the same period in 2025, representing a significant improvement in operating performance.
The company's total product sales for the three months ended March 31, 2026 were approximately $2.2 million, a decrease of $70,387 or 3% from the prior year. This decline was primarily due to lower international distributor demand, influenced by ongoing geopolitical tensions.
Revenue from China was not recognized during the current period, compared to $110,000 in the prior period. The company has received a purchase order in April 2026, indicating renewed activity in that market.
Medical revenue increased to approximately $108,000, up 110% from the prior period, reflecting continued early-stage adoption of the company’s medical products.
SEC 10-Q • 5mo ago AI analysis › Press Release
Milestone Scientific Schedules First Quarter 2026 Financial Results and Business Update Conference Call
Milestone Scientific announced it will host a conference call on May 14, 2026, at 8:30 AM ET to discuss first quarter 2026 financial results and corporate progress.
The event will be accessible via live webcast and telephone, with an audio replay available through May 28, 2026.
The company develops computerized drug delivery instruments and injection technologies for medical and dental applications.
• 5mo ago AI analysis › Press Release
Milestone Scientific Expands CompuFlo® Medical Business with Advisor Program and Growing National Clinical Adoption
Milestone Scientific provided an update on its CompuFlo business, reporting active procedures and case submissions across multiple MAC jurisdictions and commercial payers following the February launch of its Advisor Program.
The company is expanding its national sales footprint and collaborating with academic institutions like the University of Texas and Kansas to support clinical validation and broader acceptance.
Management emphasized that progress is in the early stages, focusing on building utilization and evidence to support future Category I CPT designation and long-term commercialization.
• 5mo ago AI analysis › Press Release
Milestone Scientific Inc. Completes $2.15 Million Private Placement
Milestone Scientific closed a $2.15 million private placement consisting of common stock and warrants at $0.27 per unit.
The deal included approximately $1.8 million in cash proceeds and the conversion of $351,000 in bridge notes, with insiders participating on the same terms.
Gross proceeds could reach $2.69 million if warrants are fully exercised, and the company plans to use the funds to scale sales, inventory, and marketing.
• 6mo ago AI analysis › Recent SEC filings with analysis