Hepion Pharmaceuticals, Inc. (HEPA)
Hepion Pharmaceuticals, Inc., a U.S.-based biopharmaceutical entity, is dedicated to developing therapeutic interventions for chronic hepatic ailments. Central to their efforts is Rencofilstat, a cyclophilin inhibitor that has successfully concluded Phase 2a clinical trials. This compound operates by disrupting multiple pathological pathways implicated in the worsening of liver disease. It is currently progressing through clinical development for non-alcoholic steatohepatitis (NASH) and is additionally being explored in nonclinical research for its potential to reduce liver fibrosis and lessen hepatocellular carcinoma tumor loads in experimental models of NASH. Moreover, Rencofilstat has exhibited antiviral properties against hepatitis B, C, and D viruses through diverse mechanisms. The company, established in 2013 and situated in Edison, New Jersey, rebranded as Hepion Pharmaceuticals, Inc. in July 2019, having previously operated as ContraVir Pharmaceuticals, Inc.
Sector: Pharmaceutical Preparations
Industry: Biotechnology
Hepion Pharmaceuticals, Inc.
| Date | Open | High | Low | Close | Volume |
|---|---|---|---|---|---|
based on 90.22M shares outstanding
Hepion Pharmaceuticals, Inc., a U.S.-based biopharmaceutical entity, is dedicated to developing therapeutic interventions for chronic hepatic ailments. Central to their efforts is Rencofilstat, a cyclophilin inhibitor that has successfully concluded Phase 2a clinical trials. This compound operates by disrupting multiple pathological pathways implicated in the worsening of liver disease.
It is currently progressing through clinical development for non-alcoholic steatohepatitis (NASH) and is additionally being explored in nonclinical research for its potential to reduce liver fibrosis and lessen hepatocellular carcinoma tumor loads in experimental models of NASH. Moreover, Rencofilstat has exhibited antiviral properties against hepatitis B, C, and D viruses through diverse mechanisms.
The company, established in 2013 and situated in Edison, New Jersey, rebranded as Hepion Pharmaceuticals, Inc. in July 2019, having previously operated as ContraVir Pharmaceuticals, Inc.
Leadership
Dr. Lbiati
Chief Executive Officer
Mr. Brancaccio
Executive Chairman
Gary S. Stetz
Interim Chief Executive Officer & Director
Sharen Pyatetskaya
Director of Investor Relations
Employees
2
Country
US
Sector
Healthcare
Website
hepionpharma.com
| Insider | Title | Type | Shares | Value | Date |
|---|---|---|---|---|---|
| Director | Purchase | 200.0K | -- | Sep 29, 2026 | |
| Director | Purchase | 200.0K | $10.0K | Sep 29, 2026 | |
| Executive Chairman | Purchase | 12.50M | -- | Sep 3, 2026 | |
| Director | Grant/Award | 299.0K | -- | Aug 19, 2026 | |
| Chief Operating Officer | Grant/Award | 1.35M | -- | Aug 19, 2026 | |
| Director | Grant/Award | 299.0K | -- | Aug 19, 2026 |
| Name | Shares | % | Source |
|---|---|---|---|
Vincent LoPriore · joint filing· reaffirmed 13D/A Oct 2026 | 16.3M+10.0M via warrants | 29.1% | 13D |
Gravitas Collective Corp. · may incl. warrants· filed Oct 2026 | 25.0M | 27.7% | 13D |
KI Holdings Ltd. · may incl. warrants· filed Sep 2026 | 10.0M | 11.1% | 13D |
Kenneth Rickel · filed Oct 2026 | 5.3M+2.0M via warrants | 8.0% | 13G |
Gary Stetz · filed Sep 2026 | 3.3M+2.0M via warrants | 5.8% | 13D |
Sireesh Appajosyula · filed Sep 2026 | 3.3M+2.0M via warrants | 5.8% | 13D |
Purcell Michael J. Director | 3.3M | 3.6% | FORM 4 |
LoPriore Chase VP, Corp. Dev., Director | 1.3M | 1.4% | FORM 4 |
Anson Funds Management LP · may incl. warrants· filed Aug 2025 | 576.5K | 0.6% | 13G |
Stetz Gary S. II Director | 500.0K | 0.6% | FORM 4 |
Insiders
- Fisher DaninaDirector
- LoPriore Vincent SExecutive Chairman
- Liddy James GordonDirector
- Appajosyula SireeshChief Operating Officer
- Stetz Gary S. IIDirector
- Purcell Michael J.Director
- Stetz Gary S.Interim CEO
- LoPriore ChaseVP, Corp. Dev.
Top institutional holders
based on 90.22M shares outstanding
30d Avg
26.38K
60d Avg
41.55K
90d Avg
37.87K