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PureTech Health plc (PTCHF)

PureTech Health plc operates as a clinical-stage biopharmaceutical enterprise, concentrating its efforts in the United States on the discovery, advancement, and market introduction of novel therapeutic solutions. The company's diverse pipeline targets a wide array of challenging medical conditions, including inflammatory, fibrotic, and immunological disorders, intractable cancers, various lymphatic and gastrointestinal issues, as well as neurological and neuropsychological ailments. Among its significant offerings, PureTech provides KarXT, a treatment designed to modulate muscarinic acetylcholine receptors for managing schizophrenia and the psychosis seen in Alzheimer's disease. Its technological foundations also encompass a regenerative biology platform applicable to conditions like androgenetic alopecia and epithelial aging, alongside an immunomodulation platform dedicated to addressing chronic and acute inflammatory disorders. Additionally, the firm develops oral therapies derived from specific bacterial consortia isolated from the human microbiome and treatments engineered to alleviate cognitive dysfunction associated with depression, multiple sclerosis, post-COVID and ICU recovery, and cancer-related conditions. Further innovations include hematopoietic stem cell-based therapies for individuals with blood cancer, a voice-activated technology platform capable of identifying health-related vocal shifts, and a proprietary system facilitating the oral delivery of biologics, vaccines, and other complex medications. In its robust development pipeline, PureTech is advancing LYT-100 for the treatment of lymphedema and other lymphatic flow anomalies, LYT-200 as an IgG4 monoclonal antibody targeting galectin-9, and LYT-210 for solid tumors. Pioneering technological frameworks under development include Glyph, a synthetic chemistry platform for lymphatic targeting; Orasome technology, which enables oral administration of large molecule therapeutic payloads; a meningeal lymphatics platform with implications for Alzheimer's and Parkinson's diseases; and the Alivio technology platform, designed for inflammation-targeted disease immunomodulation. PureTech Health plc has forged key collaboration and licensing agreements with leading pharmaceutical companies, including Boehringer Ingelheim International GMBH, Eli Lilly and Company, Imbrium Therapeutics L.P., and Shionogi & Co., Ltd. The company was founded in 2015 and maintains its corporate headquarters in Boston, Massachusetts.

Sector: Pharmaceutical Preparations

Industry: Biotechnology

PureTech Health plc logo

PureTech Health plc

OTC:PTCHFHealthcare
+7.43%$1.59
Mkt Cap$384.28M
Float241.68M
O/S241.68M
Inst Own-
SI<0.1%
Dilution
Delisting Issues Timeline
Financials Summary
Revenue$4.76M
Net Income-$112.18M
Total Assets$535.56M
Free Cash Flow-$87.03M
Debt & Equity
Debt 6%
Equity 94%
Total Debt$19.79M
Total Equity$312.57M
Shares Outstanding
Short Interest
Split History

No splits on record

Nothing in PTCHF's public trading history: no forward or reverse split has affected the share count.

Balance Sheet Details
Assets$535.56M
Liabilities$229.4M
Accounts Receivable$8.14M
Accounts Payable$3.07M
Inventory$0
PP&E (Net)$11.52M
Goodwill$0
Intangible Assets$601K
Income Statement
PeriodFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015FY 2014FY 2013FY 2012
CurrencyUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSD
Period Ending2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-31
Revenue$4.76M$4.32M$750K$2.09M$9.98M$8.34M$8.69M$16.37M$650K$4.43M$11.74M$2.01M$7.02M$7.93M
YoY Growth10.4%475.3%-64.1%-79.1%19.6%-4.0%-46.9%2418.6%-85.3%-62.3%483.5%-71.3%-11.5%-
Cost of Revenue$3.42M$3.5M$2.39M$152.43M$110.47M$0$85.85M$77.4M$71.03M$1.44M$714K$0$0$0
Gross Profit$1.34M$4.32M-$1.64M-$150.34M-$100.49M$8.34M-$77.16M-$61.03M-$70.39M$2.99M$11.03M$2.01M$7.02M$7.93M
Gross Margin28.1%100.0%-218.9%-7193.4%-1007.0%100.0%-888.1%-372.8%-10828.5%67.6%93.9%100.0%100.0%100.0%
Research and Development$57.83M$54.28M$96.23M$116.11M$81.52M$61.19M$65.17M$57.29M$71.67M$41.2M$13.41M$2.84M$2.83M$4.23M
Selling, General, and Administrative$20.65M$27.49M$49.53M$35.67M$30.76M$26.5M$34.89M$24.43M$46.28M$37.16M$18.38M$7.17M$3.55M$3.77M
Other$23.58M$58.64M$0$8.13M$1.65M$1.06M$121K-$278K$14K$46K$448K$0$0$0
Total Operating Expenses$102.06M$140.41M$146.95M$199.9M$160.26M$127.87M$144.09M$120.39M$116.07M$78.36M$55.38M$19.46M$10.1M$13.98M
Operating Income (EBIT)-$100.72M-$136.09M-$146.2M-$197.81M-$150.28M-$119.53M-$135.4M-$104.02M-$115.42M-$73.93M-$43.64M-$17.45M-$3.73M-$9.38M
Operating Margin-2114.7%-3154.0%-19493.2%-9464.4%-1506.0%-1433.1%-1558.5%-635.4%-17756.9%-1668.4%-371.7%-867.0%-53.2%-118.3%
Interest Expense$46.8M$10.04M$13.49M$3.95M$4.71M$2.95M$4.26M$392K$553K$801K$4.2M$2.59M$367K$609K
Interest Income$13.34M$22.67M$16.01M$5.8M$214K$1.18M$4.53M$3.36M$1.75M$1.29M$253K$46K$36K$30K
Other Income (Expense)-$12.68M$159.87M$110.1M$105.02M$91.33M$138.5M$613.87M$35.58M$44.71M-$9.25M-$12.68M-$58.78M-$1.58M-$1.39M
Income Before Tax (EBT)-$113.39M$23.77M-$36.1M-$92.78M-$58.95M$18.97M$478.47M-$68.44M-$70.71M-$83.18M-$56.32M-$76.22M-$5.31M-$10.78M
Income Tax Expense-$861K-$4.01M$30.52M-$55.72M$3.76M$14.4M$112.41M$2.22M-$14K-$1.57M$1.92M-$278K$274K$535K
Net Income-$112.18M$53.51M-$65.7M-$50.35M-$60.56M$5.99M$421.14M-$43.65M$26.47M-$48.79M-$39.39M-$41.64M-$4.3M-$11.05M
Net Income Margin-2355.4%1240.1%-8759.6%-2409.3%-606.9%71.8%4847.4%-266.7%4072.6%-1101.2%-335.5%-2069.7%-61.3%-139.4%
Supplementary Data
EPS-0.470.20-0.24-0.18-0.210.021.54-0.160.13-0.21-0.21-0.18-0.02-0.05
Diluted EPS-0.470.20-0.24-0.18-0.210.021.50-0.160.13-0.21-0.21-0.18-0.02-0.05
Weighted Average OS240.79M269.66M276.30M284.76M286.59M285.60M283.43M273.85M235.53M229.51M185.28M227.25M227.25M227.25M
EBITDA-$97.29M$37.38M-$12.03M-$51.08M-$46.95M$28.56M$487.78M-$65.27M-$67.91M-$81.17M-$49.42M-$69.35M-$4.76M-$9.67M
EBITDA Margin-2042.9%866.3%-1603.5%-2443.9%-470.5%342.4%5614.4%-398.7%-10447.4%-1831.9%-421.0%-3446.9%-67.8%-121.9%
Balance Sheet
PeriodFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015FY 2014FY 2013FY 2012
CurrencyUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSD
Period Ending2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-31
Assets
Current Assets
Cash and Cash Equivalents$254.47M$280.64M$191.08M$149.87M$465.71M$403.88M$132.36M$117.05M$72.65M$62.96M$134.75M$218.96M$7.17M$10.86M
Short-Term Investments$24.87M$86.67M$136.06M$200.23M$0$0$30.09M$133.83M$117.03M$219.41M$179.78M$1.17M$1.83M$1.18M
Cash and Short-Term Investments$279.34M$367.31M$327.14M$350.1M$465.71M$403.88M$162.45M$250.88M$189.67M$282.37M$314.53M$220.13M$9M$12.03M
Accounts Receivable$8.14M$12.9M$2.38M$12.32M$3.17M$2.94M$0$1.33M$1.8M$125K$636K$1.75M$2.67M$0
Inventory$0$0$0$0$28.01M$0$2.12M$2.2M$0$0$0-$472K-$122K$0
Other Current Assets$11.44M$1.64M$13.37M$12.16M$18.59M$2.12M$2.12M$2.2M$927K$897K$896K$0$123K$0
Total Current Assets$305.51M$386.26M$347.2M$386.19M$501.81M$414.35M$168.84M$259.79M$198.11M$288.15M$318.2M$223.72M$12.14M$13.54M
Long-Term Assets
Property, Plant & Equipment Net$11.52M$15.13M$19.36M$37.24M$43.94M$42.87M$43.84M$8.32M$6.86M$6.92M$4.52M$1.23M$1.21M$1.08M
Goodwill$0$0$0$0$0$0$0$0$0$0$0$0$0$0
Intangible Assets$601K$601K$906K$831K$987K$899K$625K$3.08M$3.31M$3.52M$3.87M$3M$3.16M$3.34M
Long-Term Investments$217.77M$107.16M$184.96M$60.81M$397.68M$531.86M$695.46M$35.93M$14.33M-$219.32M-$179.68M-$1.09M-$1.58M$40K
Deferred Tax Assets$0-$107.16M$0$217.56M-$397.68M-$531.86M$142K$449K$142K$219.41M$179.78M$1.17M$1.83M$1.18M
Other Long-Term Assets$166K$93.49M$141.54M$10K$399.27M$531.87M$32.27M$134.2M$117.1M$65K$57K$5K$3K$9K
Total Long-Term Assets$230.06M$216.38M$346.77M$316.45M$444.2M$575.64M$772.33M$181.98M$141.74M$10.6M$8.55M$4.31M$4.63M$5.64M
Other Assets$0$0$0$1K$0$1K$0$0$0$0$0$0$0$0
Total Assets$535.56M$602.63M$693.97M$702.65M$946.01M$989.99M$941.18M$441.76M$339.85M$298.75M$326.75M$228.03M$16.77M$19.18M
Liabilities
Current Liabilities
Accounts Payable$3.07M$5.52M$14.64M$26.5M$11.35M$8.87M$11.1M$4.64M$3.39M$2.08M$2.39M$1.61M$905K$1.19M
Short-Term Debt$4.92M$4.11M$3.7M$7.5M$5.5M$26.45M$1.46M$12.01M$7.46M$6.95M$4.96M$6.95M$4.26M$1.46M
Current Income Tax Payable$0$75K$0$57K$57K$1.26M$93K$0$0$0$0$0$0$0
Current Unearned Revenue$0$0-$29.46M$30.57M$31.32M$22.63M$22.21M$30.8M$129.01M$88.38M$87.05M$70.21M$7.45M$10.91M
Other Current Liabilities$31.77M$27.18M$173K$31.59M$183.33M$132.75M$92.45M$207.08M$121.04M$97.62M$61.29M$11.78M$9.14M$7.87M
Total Current Liabilities$46.38M$41.39M$51.37M$96.89M$226.13M$180.92M$139.2M$265.76M$273.86M$204.08M$160.52M$93.67M$22.76M$21.43M
Long-Term Liabilities
Long-Term Debt$0$0$0$10.24M$14.26M$14.82M$0$0$0$0$0$0$0$0
Long-Term Unearned Revenue$0$0$0$4.13M$2.66M$0$1.22M$1.37M$159K$203K$291K$561K$1.53M$1.06M
Long-Term Deferred Tax Liabilities$0$0$0$19.64M$89.77M$108.63M$115.44M$6.43M$4.4M$0$0$0$0$0
Other Long-Term Liabilities$171.91M$138.64M$166.12M$19.65M$92.42M$108.63M$0$8.67M$1.58M$2.26M$1.89M$668K$501K$48K
Total Long-Term Liabilities$183.02M$153.31M$184.37M$58.17M$135.72M$155.53M$151.58M$9.03M$1.99M$2.26M$2.18M$668K$2.03M$1.11M
Other Liabilities$0$0$0$0$0$0$0$0$0$0$0$0$0$0
Total Liabilities$229.4M$194.7M$235.74M$155.06M$361.86M$336.45M$290.78M$274.79M$275.85M$206.34M$162.7M$94.34M$24.79M$22.54M
Stockholders' Equity
Preferred Stock$0$0$0$0$0$0$0$0$0$0$0$0$0$0
Common Stock$4.87M$4.86M$5.46M$5.46M$5.44M$5.42M$5.41M$5.38M$4.68M$4.61M$4.52M$159.36M$1.27M$1.27M
Retained Earnings$61.37M$32.49M$83.82M$149.52M$199.87M$260.43M$254.44M-$167.69M-$127.87M-$160.34M-$111.42M-$70.42M-$35.06M-$30.9M
Comprehensive Income & Other$182K-$4.54M$129.15M-$14.47M-$39.53M-$23.58M-$18.28M$20.93M$34.58M$13.23M$12.77M$90.06M$32.91M$0
Other Stockholders' Equity$246.33M$377.36M$374.79M$387.25M$388.2M$403.9M$408.19M$437.82M$337.5M$333.39M$333.02M$90.06M$32.91M$32.72M
Total Equity$312.57M$414.71M$464.07M$542.22M$593.51M$669.75M$668.04M$275.51M$214.3M$177.67M$226.12M$179M-$884K$3.09M
Minority Interest-$6.41M-$6.77M-$5.83M$5.37M-$9.37M-$16.21M-$17.64M-$108.53M-$150.31M-$85.25M-$62.07M-$45.32M-$7.14M-$6.45M
Total Liabilities and Equity$541.97M$609.41M$699.81M$697.28M$955.37M$1.01B$958.82M$550.3M$490.15M$384M$388.82M$273.35M$23.91M$25.63M
Supplementary Data
Total Debt$19.79M$22.36M$25.34M$46.87M$52.02M$76.62M$39.3M$12.37M$7.46M$6.95M$4.96M$6.95M$4.26M$1.46M
Net Debt-$234.68M-$258.28M-$165.74M-$102.99M-$413.68M-$327.26M-$93.06M-$104.68M-$65.19M-$56.01M-$129.8M-$212.01M-$2.91M-$9.4M
Cash Flow Statement
PeriodFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015FY 2014FY 2013FY 2012
CurrencyUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSDUSD
Period Ending2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-312015-12-312014-12-312013-12-312012-12-31
Operating Activities
Net Income-$110.08M$27.78M-$67.28M-$37.06M-$62.71M$4.57M$366.06M-$70.66M-$70.7M-$81.61M-$58.24M-$75.94M-$5.16M-$12.25M
Depreciation & Amortization$3.42M$3.57M$4.93M$8.89M$7.29M$6.64M$6.67M$2.78M$2.1M$1.57M$740K$455K$453K$500K
Deferred Income Tax$0$0$0-$179.39M-$112.61M-$151.35M-$546.61M-$19.42M-$116.81M-$783K-$383K$233K$1.36M$3.25M
Stock-Based Compensation$8.22M$22.85M$4.42M$14.7M$13.95M$10.72M$14.47M$12.64M$11.85M$10.15M$11.1M$2.81M$290K$408K
Changes in Working Capital:
  Accounts Receivable-$241K$629K$9.75M-$7.59M-$606K-$564K$776K$446K-$1.76M$532K$1.07M$794K-$2.33M$0
  Inventory$0$0$0$289K-$87K$562K-$577K$0$0$0$0$0$0$0
  Accounts Payable-$1.05M$0$0$21.63M$8.2M$645K$11.59M$4.87M$5.5M$3.23M$4.17M$0$0$0
  Other Working Capital-$1.9M-$10.87M$7.77M$1.59M-$6.64M-$9.17M$3.23M$4.21M-$626K-$1.99M-$260K-$1.38M$1.24M$0
Total Working Capital Change-$3.19M-$10.24M$17.52M$15.92M$861K-$8.53M$15.03M$9.96M$2.97M$1.94M$4.81M$2.87M-$5.96M$5.13M
Other Non-Cash Items$14.61M-$178.34M-$65.5M-$1.85M-$5.05M$6.11M$46.23M-$8.1M$81.9M$10.7M$12.99M$59.26M$1.61M$4.76M
Net Cash from Operating-$87.02M-$134.37M-$105.92M-$178.79M-$158.27M-$131.83M-$98.16M-$72.8M-$88.69M-$58.03M-$28.61M-$10.54M-$8.77M-$1.45M
Investing Activities
Capital Expenditures-$6K-$11K-$70K-$2.18M-$5.66M-$5.42M-$12.54M-$4.49M-$2.17M-$3.68M-$4.61M-$420K-$588K-$1.45M
Acquisitions$275K-$105.97M-$13.23M-$20.44M$321K-$10M-$16.04M-$13.39M-$16.34M$0$0$0$79K$0
Purchases of Investments-$86.98M-$309.6M-$200.43M-$268.73M-$500K-$1.15M-$91.25M-$169.95M-$147.2M-$312.82M-$385.38M-$2.22M-$3.49M-$2.52M
Sales of Investments$151.36M$656.22M$277.87M$183.71M$218.13M$380.7M$183.29M$148.06M$249.4M$273.27M$205.75M$3.39M$3.08M$3.77M
Other Investing Activities$50K$255K$4.85M$416K-$14.91M$350K$191K$125K-$80K-$39.55M-$1.16M-$53K$54K-$617K
Net Cash from Investing$64.7M$240.89M$68.99M-$107.22M$197.38M$364.48M$63.66M-$39.65M$83.68M-$43.23M-$184.24M$747K-$858K-$200K
Financing Activities
Debt Repaid----$393K-$2.21M-$11.88M-$1.43M-$5.96M-$2.45M-$2.06M-$1.48M-$7.59M-$1.78M$2.05M
Common Stock Issuance$108K$895K$1.15M$332K$0-$11.76M$0$152.03M$12.4M$27.26M$235.66M$55.84M$0$698K
Common Stock Repurchases-$2.1M-$107.56M-$19.65M-$26.49M-$13.33M$0-$1.28M-$35K-$66K$0$0$0$0$0
Dividends Paid$0$0$0$0$0$0-$112K$0-$91K-$100K$0-$96K-$2K-$136K
Other Financing Activities-$4.48M$89.71M$97.79M-$4.54M$33.84M$25M-$1.79M-$1.07M$0-$100K$48.8M-$174K$4.11M$2.74M
Net Cash from Financing-$6.47M-$16.96M$78.14M-$29.83M$22.73M$38.87M$49.91M$156.89M$14.7M$29.49M$285.94M$64.72M$5.94M$1.26M
Forex Effect$1.28M$0$0$0-$1K$1K-$104K-$44K-$3K-$16K-$294K-$138K$9K-$7K
Net Change in Cash-$27.52M$89.56M$41.22M-$315.84M$61.83M$271.52M$15.31M$44.4M$9.69M-$71.79M$72.79M$54.79M-$3.68M-$403K
Supplementary Data
Operating Cash Flow-$87.02M-$134.37M-$105.92M-$178.79M-$158.27M-$131.83M-$98.16M-$72.8M-$88.69M-$58.03M-$28.61M-$10.54M-$8.77M-$1.45M
Capital Expenditure-$6K-$11K-$245K-$2.18M-$5.66M-$5.42M-$12.54M-$4.49M-$2.17M-$3.68M-$4.61M-$420K-$588K-$1.45M
Free Cash Flow-$87.03M-$134.38M-$106.16M-$180.97M-$163.94M-$137.25M-$110.69M-$77.29M-$90.86M-$61.71M-$33.22M-$10.96M-$9.36M-$2.9M
Cash at Beginning$281.99M$191.08M$149.87M$465.71M$403.88M$132.36M$117.05M$72.65M$62.96M$134.75M$61.96M$7.17M$10.86M$11.26M
Cash at End$254.47M$280.64M$191.08M$149.87M$465.71M$403.88M$132.36M$117.05M$72.65M$62.96M$134.75M$61.96M$7.17M$10.86M