Siren, L.L.C.

Siren, L.L.C. is an Investment Adviser institutional filer with the SEC under CIK 2005245, reporting 115 portfolio positions, with 14 historical 13F filings on file. Most recent reporting period: 2026-06-30.

A Form 13F reports a manager's US-listed stock and option positions only. It does not include real estate, private funds, bonds, cash or non-US holdings, so a 13F portfolio value is not the firm's total assets under management (AUM).

• State of incorporation: DE
• Filing type: 13F-HR
• Latest reporting period: 2026-06-30
• Last filed: 2026-08-13

Top 10 portfolio positions

The largest reported holdings in Siren, L.L.C.'s most recent 13F filing, ranked by reported market value.

1. Scholar Rock Holding Corp (SRRK)
2. Kymera Therapeutics Inc (KYMR)
3. Erasca Inc (ERAS)
4. Veradermics Inc (MANE)
5. Tango Therapeutics Inc (TNGX)
6. Revolution Medicines Inc (RVMD)
7. Bicara Therapeutics Inc (BCAX)
8. Arrowhead Pharmaceuticals Inc (ARWR)
9. BeOne Medicines AG (ONC)
10. Edgewise Therapeutics Inc (EWTX)